Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HPGDS (hematopoietic prostaglandin D synthase)

Identity

Alias_symbol (synonym)GSTS
PGDS
H-PGDS
PGD2
GSTS1-1
GSTS1
Other alias
HGNC (Hugo) HPGDS
LocusID (NCBI) 27306
Atlas_Id 52862
Location 4q22.3  [Link to chromosome band 4q22]
Location_base_pair Starts at 94298556 and ends at 94342876 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HPGDS   17890
Cards
Entrez_Gene (NCBI)HPGDS  27306  hematopoietic prostaglandin D synthase
AliasesGSTS; GSTS1; GSTS1-1; PGD2; 
PGDS
GeneCards (Weizmann)HPGDS
Ensembl hg19 (Hinxton)ENSG00000163106 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163106 [Gene_View]  chr4:94298556-94342876 [Contig_View]  HPGDS [Vega]
ICGC DataPortalENSG00000163106
TCGA cBioPortalHPGDS
AceView (NCBI)HPGDS
Genatlas (Paris)HPGDS
WikiGenes27306
SOURCE (Princeton)HPGDS
Genetics Home Reference (NIH)HPGDS
Genomic and cartography
GoldenPath hg38 (UCSC)HPGDS  -     chr4:94298556-94342876 -  4q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HPGDS  -     4q22.3   [Description]    (hg19-Feb_2009)
EnsemblHPGDS - 4q22.3 [CytoView hg19]  HPGDS - 4q22.3 [CytoView hg38]
Mapping of homologs : NCBIHPGDS [Mapview hg19]  HPGDS [Mapview hg38]
OMIM602598   
Gene and transcription
Genbank (Entrez)AK290075 BC020734 CB988786 CR541662 CR541679
RefSeq transcript (Entrez)NM_014485
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HPGDS
Cluster EST : UnigeneHs.128433 [ NCBI ]
CGAP (NCI)Hs.128433
Alternative Splicing GalleryENSG00000163106
Gene ExpressionHPGDS [ NCBI-GEO ]   HPGDS [ EBI - ARRAY_EXPRESS ]   HPGDS [ SEEK ]   HPGDS [ MEM ]
Gene Expression Viewer (FireBrowse)HPGDS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27306
GTEX Portal (Tissue expression)HPGDS
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60760   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60760  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60760
Splice isoforms : SwissVarO60760
PhosPhoSitePlusO60760
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    GST_C    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GST_C_3 (PF14497)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam14497    pfam02798   
Conserved Domain (NCBI)HPGDS
DMDM Disease mutations27306
Blocks (Seattle)HPGDS
PDB (SRS)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX   
PDB (PDBSum)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX   
PDB (IMB)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX   
PDB (RSDB)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX   
Structural Biology KnowledgeBase1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX   
SCOP (Structural Classification of Proteins)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX   
CATH (Classification of proteins structures)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX   
SuperfamilyO60760
Human Protein AtlasENSG00000163106
Peptide AtlasO60760
HPRD04001
IPIIPI00219303   
Protein Interaction databases
DIP (DOE-UCLA)O60760
IntAct (EBI)O60760
FunCoupENSG00000163106
BioGRIDHPGDS
STRING (EMBL)HPGDS
ZODIACHPGDS
Ontologies - Pathways
QuickGOO60760
Ontology : AmiGOmagnesium ion binding  glutathione transferase activity  prostaglandin-D synthase activity  prostaglandin-D synthase activity  calcium ion binding  protein binding  cytoplasm  cytosol  prostaglandin metabolic process  signal transduction  locomotory behavior  cyclooxygenase pathway  protein homodimerization activity  glutathione derivative biosynthetic process  negative regulation of male germ cell proliferation  
Ontology : EGO-EBImagnesium ion binding  glutathione transferase activity  prostaglandin-D synthase activity  prostaglandin-D synthase activity  calcium ion binding  protein binding  cytoplasm  cytosol  prostaglandin metabolic process  signal transduction  locomotory behavior  cyclooxygenase pathway  protein homodimerization activity  glutathione derivative biosynthetic process  negative regulation of male germ cell proliferation  
Pathways : BIOCARTAEicosanoid Metabolism [Genes]   
Pathways : KEGGArachidonic acid metabolism   
NDEx NetworkHPGDS
Atlas of Cancer Signalling NetworkHPGDS
Wikipedia pathwaysHPGDS
Orthology - Evolution
OrthoDB27306
GeneTree (enSembl)ENSG00000163106
Phylogenetic Trees/Animal Genes : TreeFamHPGDS
HOVERGENO60760
HOGENOMO60760
Homologs : HomoloGeneHPGDS
Homology/Alignments : Family Browser (UCSC)HPGDS
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHPGDS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HPGDS
dbVarHPGDS
ClinVarHPGDS
1000_GenomesHPGDS 
Exome Variant ServerHPGDS
ExAC (Exome Aggregation Consortium)HPGDS (select the gene name)
Genetic variants : HAPMAP27306
Genomic Variants (DGV)HPGDS [DGVbeta]
DECIPHERHPGDS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHPGDS 
Mutations
ICGC Data PortalHPGDS 
TCGA Data PortalHPGDS 
Broad Tumor PortalHPGDS
OASIS PortalHPGDS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHPGDS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHPGDS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch HPGDS
DgiDB (Drug Gene Interaction Database)HPGDS
DoCM (Curated mutations)HPGDS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HPGDS (select a term)
intoGenHPGDS
Cancer3DHPGDS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602598   
Orphanet
MedgenHPGDS
Genetic Testing Registry HPGDS
NextProtO60760 [Medical]
TSGene27306
GENETestsHPGDS
Target ValidationHPGDS
Huge Navigator HPGDS [HugePedia]
snp3D : Map Gene to Disease27306
BioCentury BCIQHPGDS
ClinGenHPGDS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27306
Chemical/Pharm GKB GenePA165664133
Clinical trialHPGDS
Miscellaneous
canSAR (ICR)HPGDS (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHPGDS
EVEXHPGDS
GoPubMedHPGDS
iHOPHPGDS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:12:14 CEST 2017

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