Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HPGDS (hematopoietic prostaglandin D synthase)

Identity

Alias (NCBI)GSTS
GSTS1
GSTS1-1
PGD2
PGDS
HGNC (Hugo) HPGDS
HGNC Alias symbGSTS
PGDS
H-PGDS
PGD2
GSTS1-1
GSTS1
HGNC Alias nameglutathione S-transferase sigma
LocusID (NCBI) 27306
Atlas_Id 52862
Location 4q22.3  [Link to chromosome band 4q22]
Location_base_pair Starts at 94298535 and ends at 94342836 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)HPGDS   17890
Cards
Entrez_Gene (NCBI)HPGDS  27306  hematopoietic prostaglandin D synthase
AliasesGSTS; GSTS1; GSTS1-1; PGD2; 
PGDS
GeneCards (Weizmann)HPGDS
Ensembl hg19 (Hinxton)ENSG00000163106 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163106 [Gene_View]  ENSG00000163106 [Sequence]  chr4:94298535-94342836 [Contig_View]  HPGDS [Vega]
ICGC DataPortalENSG00000163106
TCGA cBioPortalHPGDS
AceView (NCBI)HPGDS
Genatlas (Paris)HPGDS
WikiGenes27306
SOURCE (Princeton)HPGDS
Genetics Home Reference (NIH)HPGDS
Genomic and cartography
GoldenPath hg38 (UCSC)HPGDS  -     chr4:94298535-94342836 -  4q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HPGDS  -     4q22.3   [Description]    (hg19-Feb_2009)
GoldenPathHPGDS - 4q22.3 [CytoView hg19]  HPGDS - 4q22.3 [CytoView hg38]
ImmunoBaseENSG00000163106
genome Data Viewer NCBIHPGDS [Mapview hg19]  
OMIM602598   
Gene and transcription
Genbank (Entrez)AK290075 BC020734 CB988786 CR541662 CR541679
RefSeq transcript (Entrez)NM_014485
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HPGDS
Alternative Splicing GalleryENSG00000163106
Gene ExpressionHPGDS [ NCBI-GEO ]   HPGDS [ EBI - ARRAY_EXPRESS ]   HPGDS [ SEEK ]   HPGDS [ MEM ]
Gene Expression Viewer (FireBrowse)HPGDS [ Firebrowse - Broad ]
GenevisibleExpression of HPGDS in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27306
GTEX Portal (Tissue expression)HPGDS
Human Protein AtlasENSG00000163106-HPGDS [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60760   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60760  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60760
Splice isoforms : SwissVarO60760
PhosPhoSitePlusO60760
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione-S-Trfase_C_sf    Glutathione_S-Trfase_N    GST_C    Thioredoxin-like_sf   
Domain families : Pfam (Sanger)GST_C_3 (PF14497)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam14497    pfam02798   
Conserved Domain (NCBI)HPGDS
DMDM Disease mutations27306
Blocks (Seattle)HPGDS
PDB (RSDB)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX    5YWE    5YWX    5YX1    6N4E   
PDB Europe1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX    5YWE    5YWX    5YX1    6N4E   
PDB (PDBSum)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX    5YWE    5YWX    5YX1    6N4E   
PDB (IMB)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX    5YWE    5YWX    5YX1    6N4E   
Structural Biology KnowledgeBase1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX    5YWE    5YWX    5YX1    6N4E   
SCOP (Structural Classification of Proteins)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX    5YWE    5YWX    5YX1    6N4E   
CATH (Classification of proteins structures)1IYH    1IYI    1V40    2CVD    2VCQ    2VCW    2VCX    2VCZ    2VD0    2VD1    3EE2    3KXO    3VI5    3VI7    4EC0    4EDY    4EDZ    4EE0    5AIS    5AIV    5AIX    5YWE    5YWX    5YX1    6N4E   
SuperfamilyO60760
Human Protein Atlas [tissue]ENSG00000163106-HPGDS [tissue]
Peptide AtlasO60760
HPRD04001
IPIIPI00219303   
Protein Interaction databases
DIP (DOE-UCLA)O60760
IntAct (EBI)O60760
FunCoupENSG00000163106
BioGRIDHPGDS
STRING (EMBL)HPGDS
ZODIACHPGDS
Ontologies - Pathways
QuickGOO60760
Ontology : AmiGOmagnesium ion binding  glutathione transferase activity  prostaglandin-D synthase activity  calcium ion binding  protein binding  nucleoplasm  cytoplasm  cytosol  cytosol  prostaglandin metabolic process  glutathione metabolic process  signal transduction  locomotory behavior  cyclooxygenase pathway  protein homodimerization activity  intracellular membrane-bounded organelle  glutathione derivative biosynthetic process  negative regulation of male germ cell proliferation  
Ontology : EGO-EBImagnesium ion binding  glutathione transferase activity  prostaglandin-D synthase activity  calcium ion binding  protein binding  nucleoplasm  cytoplasm  cytosol  cytosol  prostaglandin metabolic process  glutathione metabolic process  signal transduction  locomotory behavior  cyclooxygenase pathway  protein homodimerization activity  intracellular membrane-bounded organelle  glutathione derivative biosynthetic process  negative regulation of male germ cell proliferation  
Pathways : KEGGArachidonic acid metabolism   
NDEx NetworkHPGDS
Atlas of Cancer Signalling NetworkHPGDS
Wikipedia pathwaysHPGDS
Orthology - Evolution
OrthoDB27306
GeneTree (enSembl)ENSG00000163106
Phylogenetic Trees/Animal Genes : TreeFamHPGDS
HOGENOMO60760
Homologs : HomoloGeneHPGDS
Homology/Alignments : Family Browser (UCSC)HPGDS
Gene fusions - Rearrangements
Fusion : QuiverHPGDS
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHPGDS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HPGDS
dbVarHPGDS
ClinVarHPGDS
MonarchHPGDS
1000_GenomesHPGDS 
Exome Variant ServerHPGDS
GNOMAD BrowserENSG00000163106
Varsome BrowserHPGDS
Genetic variants : HAPMAP27306
Genomic Variants (DGV)HPGDS [DGVbeta]
DECIPHERHPGDS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHPGDS 
Mutations
ICGC Data PortalHPGDS 
TCGA Data PortalHPGDS 
Broad Tumor PortalHPGDS
OASIS PortalHPGDS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHPGDS  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHPGDS
Mutations and Diseases : HGMDHPGDS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch HPGDS
DgiDB (Drug Gene Interaction Database)HPGDS
DoCM (Curated mutations)HPGDS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HPGDS (select a term)
intoGenHPGDS
Cancer3DHPGDS(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602598   
Orphanet
DisGeNETHPGDS
MedgenHPGDS
Genetic Testing Registry HPGDS
NextProtO60760 [Medical]
TSGene27306
GENETestsHPGDS
Target ValidationHPGDS
Huge Navigator HPGDS [HugePedia]
snp3D : Map Gene to Disease27306
BioCentury BCIQHPGDS
ClinGenHPGDS
Clinical trials, drugs, therapy
Protein Interactions : CTD27306
Pharm GKB GenePA165664133
Pharm GKB PathwaysPA152241951   PA166121942   
Clinical trialHPGDS
Miscellaneous
canSAR (ICR)HPGDS (select the gene name)
HarmonizomeHPGDS
DataMed IndexHPGDS
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHPGDS
EVEXHPGDS
GoPubMedHPGDS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 14 14:14:50 CEST 2020

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