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HPR (haptoglobin-related protein)

Identity

Other aliasA-259H10.2
HP
HGNC (Hugo) HPR
LocusID (NCBI) 3250
Atlas_Id 53009
Location 16q22.2  [Link to chromosome band 16q22]
Location_base_pair Starts at 72097125 and ends at 72111145 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HPR (16q22.2) / MRPS10 (6p21.1)MRPS10 (6p21.1) / HPR (16q22.2)RPS10 (6p21.31) / HPR (16q22.2)
SLC25A19 (17q25.1) / HPR (16q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Prostate tumors: an overview


External links

Nomenclature
HGNC (Hugo)HPR   5156
Cards
Entrez_Gene (NCBI)HPR  3250  haptoglobin-related protein
AliasesA-259H10.2; HP
GeneCards (Weizmann)HPR
Ensembl hg19 (Hinxton)ENSG00000261701 [Gene_View]  chr16:72097125-72111145 [Contig_View]  HPR [Vega]
Ensembl hg38 (Hinxton)ENSG00000261701 [Gene_View]  chr16:72097125-72111145 [Contig_View]  HPR [Vega]
ICGC DataPortalENSG00000261701
TCGA cBioPortalHPR
AceView (NCBI)HPR
Genatlas (Paris)HPR
WikiGenes3250
SOURCE (Princeton)HPR
Genetics Home Reference (NIH)HPR
Genomic and cartography
GoldenPath hg19 (UCSC)HPR  -     chr16:72097125-72111145 +  16q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HPR  -     16q22.2   [Description]    (hg38-Dec_2013)
EnsemblHPR - 16q22.2 [CytoView hg19]  HPR - 16q22.2 [CytoView hg38]
Mapping of homologs : NCBIHPR [Mapview hg19]  HPR [Mapview hg38]
OMIM140210   
Gene and transcription
Genbank (Entrez)AV698541 BC160066 BM547990 CB115435 CB147217
RefSeq transcript (Entrez)NM_020995
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_030311 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)HPR
Cluster EST : UnigeneHs.655361 [ NCBI ]
CGAP (NCI)Hs.655361
Alternative Splicing GalleryENSG00000261701
Gene ExpressionHPR [ NCBI-GEO ]   HPR [ EBI - ARRAY_EXPRESS ]   HPR [ SEEK ]   HPR [ MEM ]
Gene Expression Viewer (FireBrowse)HPR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3250
GTEX Portal (Tissue expression)HPR
Protein : pattern, domain, 3D structure
UniProt/SwissProtP00739   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP00739  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP00739
Splice isoforms : SwissVarP00739
PhosPhoSitePlusP00739
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)   
Domains : Interpro (EBI)Haptoglobin    Peptidase_S1_PA    Peptidase_S1A    Sushi_SCR_CCP_dom    Trypsin_dom   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)HPR
DMDM Disease mutations3250
Blocks (Seattle)HPR
SuperfamilyP00739
Human Protein AtlasENSG00000261701
Peptide AtlasP00739
HPRD00773
IPIIPI00641737   IPI00478493   
Protein Interaction databases
DIP (DOE-UCLA)P00739
IntAct (EBI)P00739
FunCoupENSG00000261701
BioGRIDHPR
STRING (EMBL)HPR
ZODIACHPR
Ontologies - Pathways
QuickGOP00739
Ontology : AmiGOpositive regulation of defense response to virus by host  serine-type endopeptidase activity  extracellular region  proteolysis  receptor-mediated endocytosis  hemoglobin binding  spherical high-density lipoprotein particle  extracellular exosome  blood microparticle  mitophagy in response to mitochondrial depolarization  xenophagy  
Ontology : EGO-EBIpositive regulation of defense response to virus by host  serine-type endopeptidase activity  extracellular region  proteolysis  receptor-mediated endocytosis  hemoglobin binding  spherical high-density lipoprotein particle  extracellular exosome  blood microparticle  mitophagy in response to mitochondrial depolarization  xenophagy  
Pathways : KEGGAfrican trypanosomiasis   
NDEx NetworkHPR
Atlas of Cancer Signalling NetworkHPR
Wikipedia pathwaysHPR
Orthology - Evolution
OrthoDB3250
GeneTree (enSembl)ENSG00000261701
Phylogenetic Trees/Animal Genes : TreeFamHPR
HOVERGENP00739
HOGENOMP00739
Homologs : HomoloGeneHPR
Homology/Alignments : Family Browser (UCSC)HPR
Gene fusions - Rearrangements
Fusion : MitelmanMRPS10/HPR [6p21.1/16q22.2]  [t(6;16)(p21;q22)]  
Fusion : MitelmanRPS10/HPR [6p21.31/16q22.2]  [t(6;16)(p21;q22)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHPR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HPR
dbVarHPR
ClinVarHPR
1000_GenomesHPR 
Exome Variant ServerHPR
ExAC (Exome Aggregation Consortium)HPR (select the gene name)
Genetic variants : HAPMAP3250
Genomic Variants (DGV)HPR [DGVbeta]
DECIPHER (Syndromes)16:72097125-72111145  ENSG00000261701
CONAN: Copy Number AnalysisHPR 
Mutations
ICGC Data PortalHPR 
TCGA Data PortalHPR 
Broad Tumor PortalHPR
OASIS PortalHPR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHPR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHPR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HPR
DgiDB (Drug Gene Interaction Database)HPR
DoCM (Curated mutations)HPR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HPR (select a term)
intoGenHPR
Cancer3DHPR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM140210   
Orphanet
MedgenHPR
Genetic Testing Registry HPR
NextProtP00739 [Medical]
TSGene3250
GENETestsHPR
Huge Navigator HPR [HugePedia]
snp3D : Map Gene to Disease3250
BioCentury BCIQHPR
ClinGenHPR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3250
Chemical/Pharm GKB GenePA29426
Clinical trialHPR
Miscellaneous
canSAR (ICR)HPR (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHPR
EVEXHPR
GoPubMedHPR
iHOPHPR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:09:42 CET 2017

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