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HPSE2 (heparanase 2 (inactive))

Identity

Other namesHPA2
HPR2
UFS
UFS1
HGNC (Hugo) HPSE2
LocusID (NCBI) 60495
Location 10q24.2
Location_base_pair Starts at 100216834 and ends at 100995632 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)HPSE2   18374
Cards
Entrez_Gene (NCBI)HPSE2  60495  heparanase 2 (inactive)
GeneCards (Weizmann)HPSE2
Ensembl (Hinxton) [Gene_View]  chr10:100216834-100995632 [Contig_View]  HPSE2 [Vega]
cBioPortalHPSE2
AceView (NCBI)HPSE2
Genatlas (Paris)HPSE2
WikiGenes60495
SOURCE (Princeton)NM_001166244 NM_001166245 NM_001166246 NM_021828
Genomic and cartography
GoldenPath (UCSC)HPSE2  -  10q24.2   chr10:100216834-100995632 -  10q24.2   [Description]    (hg19-Feb_2009)
EnsemblHPSE2 - 10q24.2 [CytoView]
Mapping of homologs : NCBIHPSE2 [Mapview]
OMIM236730   613469   
Gene and transcription
Genbank (Entrez)AF282885 AF282886 AF282887 AJ299719 AJ299720
RefSeq transcript (Entrez)NM_001166244 NM_001166245 NM_001166246 NM_021828
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NG_023416 NT_030059 NW_001838005 NW_001838006 NW_004929376
Consensus coding sequences : CCDS (NCBI)HPSE2
Cluster EST : UnigeneHs.689544 [ NCBI ]
CGAP (NCI)Hs.689544
Alternative Splicing : Fast-db (Paris)GSHG0004297
Gene ExpressionHPSE2 [ NCBI-GEO ]     HPSE2 [ SEEK ]   HPSE2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWQ2 (Uniprot)
NextProtQ8WWQ2  [Medical]
With graphics : InterProQ8WWQ2
Splice isoforms : SwissVarQ8WWQ2 (Swissvar)
Domains : Interpro (EBI)Glyco_hydro_79 [organisation]   Glyco_hydro_catalytic_dom [organisation]   Glycoside_hydrolase_SF [organisation]  
Related proteins : CluSTrQ8WWQ2
Domain families : Pfam (Sanger)Glyco_hydro_79n (PF03662)   
Domain families : Pfam (NCBI)pfam03662   
DMDM Disease mutations60495
Blocks (Seattle)Q8WWQ2
Peptide AtlasQ8WWQ2
HPRD13669
IPIIPI00029594   IPI00642713   IPI00157363   IPI00157364   
Protein Interaction databases
DIP (DOE-UCLA)Q8WWQ2
IntAct (EBI)Q8WWQ2
BioGRIDHPSE2
InParanoidQ8WWQ2
Interologous Interaction database Q8WWQ2
IntegromeDBHPSE2
STRING (EMBL)HPSE2
Ontologies - Pathways
Ontology : AmiGOproteinaceous extracellular matrix  intracellular  plasma membrane  carbohydrate metabolic process  glycosaminoglycan catabolic process  biological_process  glycosaminoglycan metabolic process  heparanase activity  heparanase activity  heparan sulfate proteoglycan binding  small molecule metabolic process  
Ontology : EGO-EBIproteinaceous extracellular matrix  intracellular  plasma membrane  carbohydrate metabolic process  glycosaminoglycan catabolic process  biological_process  glycosaminoglycan metabolic process  heparanase activity  heparanase activity  heparan sulfate proteoglycan binding  small molecule metabolic process  
Pathways : KEGGGlycosaminoglycan degradation    Proteoglycans in cancer   
Protein Interaction DatabaseHPSE2
Wikipedia pathwaysHPSE2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)HPSE2
snp3D : Map Gene to Disease60495
SNP (GeneSNP Utah)HPSE2
SNP : HGBaseHPSE2
Genetic variants : HAPMAPHPSE2
Exome VariantHPSE2
1000_GenomesHPSE2 
Somatic Mutations in Cancer : COSMICHPSE2 
CONAN: Copy Number AnalysisHPSE2 
Mutations and Diseases : HGMDHPSE2
Mutations and Diseases : intOGenHPSE2
Genomic VariantsHPSE2  HPSE2 [DGVbeta]
dbVarHPSE2
ClinVarHPSE2
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM236730    613469   
MedgenHPSE2
GENETestsHPSE2
Disease Genetic AssociationHPSE2
Huge Navigator HPSE2 [HugePedia]  HPSE2 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneHPSE2
Homology/Alignments : Family Browser (UCSC)HPSE2
Phylogenetic Trees/Animal Genes : TreeFamHPSE2
Chemical/Protein Interactions : CTD60495
Chemical/Pharm GKB GenePA38533
Clinical trialHPSE2
Other databases
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
CoreMineHPSE2
iHOPHPSE2
OncoSearchHPSE2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:49:57 CEST 2014

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