Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HPX (hemopexin)

Identity

Other aliasHX
HGNC (Hugo) HPX
LocusID (NCBI) 3263
Atlas_Id 55516
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 6431038 and ends at 6441024 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPM6A (4q34.2) / HPX (11p15.4)HPX (11p15.4) / R3HDM1 (2q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HPX   5171
Cards
Entrez_Gene (NCBI)HPX  3263  hemopexin
AliasesHX
GeneCards (Weizmann)HPX
Ensembl hg19 (Hinxton)ENSG00000110169 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110169 [Gene_View]  ENSG00000110169 [Sequence]  chr11:6431038-6441024 [Contig_View]  HPX [Vega]
ICGC DataPortalENSG00000110169
TCGA cBioPortalHPX
AceView (NCBI)HPX
Genatlas (Paris)HPX
WikiGenes3263
SOURCE (Princeton)HPX
Genetics Home Reference (NIH)HPX
Genomic and cartography
GoldenPath hg38 (UCSC)HPX  -     chr11:6431038-6441024 -  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HPX  -     11p15.4   [Description]    (hg19-Feb_2009)
HPX - 11p15.4 [CytoView hg19]  HPX - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBIHPX [Mapview hg19]  HPX [Mapview hg38]
OMIM142290   
Gene and transcription
Genbank (Entrez)AK303758 AK313648 AV655383 BC005395 GQ891443
RefSeq transcript (Entrez)NM_000613
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HPX
Cluster EST : UnigeneHs.426485 [ NCBI ]
CGAP (NCI)Hs.426485
Alternative Splicing GalleryENSG00000110169
Gene ExpressionHPX [ NCBI-GEO ]   HPX [ EBI - ARRAY_EXPRESS ]   HPX [ SEEK ]   HPX [ MEM ]
Gene Expression Viewer (FireBrowse)HPX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3263
GTEX Portal (Tissue expression)HPX
Human Protein AtlasENSG00000110169-HPX [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02790   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02790  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02790
Splice isoforms : SwissVarP02790
PhosPhoSitePlusP02790
Domaine pattern : Prosite (Expaxy)HEMOPEXIN (PS00024)    HEMOPEXIN_2 (PS51642)   
Domains : Interpro (EBI)Hemopexin    Hemopexin-like_dom    Hemopexin-like_dom_sf    Hemopexin-like_repeat    Hemopexin_CS   
Domain families : Pfam (Sanger)Hemopexin (PF00045)   
Domain families : Pfam (NCBI)pfam00045   
Domain families : Smart (EMBL)HX (SM00120)  
Conserved Domain (NCBI)HPX
DMDM Disease mutations3263
Blocks (Seattle)HPX
SuperfamilyP02790
Human Protein Atlas [tissue]ENSG00000110169-HPX [tissue]
Peptide AtlasP02790
HPRD00793
IPIIPI00022488   IPI01015184   
Protein Interaction databases
DIP (DOE-UCLA)P02790
IntAct (EBI)P02790
FunCoupENSG00000110169
BioGRIDHPX
STRING (EMBL)HPX
ZODIACHPX
Ontologies - Pathways
QuickGOP02790
Ontology : AmiGOpositive regulation of immunoglobulin production  positive regulation of humoral immune response mediated by circulating immunoglobulin  protein binding  extracellular region  extracellular region  extracellular space  extracellular space  extracellular space  proteolysis  cellular iron ion homeostasis  receptor-mediated endocytosis  heme transporter activity  heme transport  viral process  heme metabolic process  positive regulation of tyrosine phosphorylation of STAT protein  metal ion binding  positive regulation of interferon-gamma-mediated signaling pathway  collagen-containing extracellular matrix  extracellular exosome  endocytic vesicle lumen  blood microparticle  
Ontology : EGO-EBIpositive regulation of immunoglobulin production  positive regulation of humoral immune response mediated by circulating immunoglobulin  protein binding  extracellular region  extracellular region  extracellular space  extracellular space  extracellular space  proteolysis  cellular iron ion homeostasis  receptor-mediated endocytosis  heme transporter activity  heme transport  viral process  heme metabolic process  positive regulation of tyrosine phosphorylation of STAT protein  metal ion binding  positive regulation of interferon-gamma-mediated signaling pathway  collagen-containing extracellular matrix  extracellular exosome  endocytic vesicle lumen  blood microparticle  
NDEx NetworkHPX
Atlas of Cancer Signalling NetworkHPX
Wikipedia pathwaysHPX
Orthology - Evolution
OrthoDB3263
GeneTree (enSembl)ENSG00000110169
Phylogenetic Trees/Animal Genes : TreeFamHPX
HOGENOMP02790
Homologs : HomoloGeneHPX
Homology/Alignments : Family Browser (UCSC)HPX
Gene fusions - Rearrangements
Fusion : QuiverHPX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHPX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HPX
dbVarHPX
ClinVarHPX
1000_GenomesHPX 
Exome Variant ServerHPX
ExAC (Exome Aggregation Consortium)ENSG00000110169
GNOMAD BrowserENSG00000110169
Varsome BrowserHPX
Genetic variants : HAPMAP3263
Genomic Variants (DGV)HPX [DGVbeta]
DECIPHERHPX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHPX 
Mutations
ICGC Data PortalHPX 
TCGA Data PortalHPX 
Broad Tumor PortalHPX
OASIS PortalHPX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHPX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHPX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HPX
DgiDB (Drug Gene Interaction Database)HPX
DoCM (Curated mutations)HPX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HPX (select a term)
intoGenHPX
Cancer3DHPX(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142290   
Orphanet
DisGeNETHPX
MedgenHPX
Genetic Testing Registry HPX
NextProtP02790 [Medical]
TSGene3263
GENETestsHPX
Target ValidationHPX
Huge Navigator HPX [HugePedia]
snp3D : Map Gene to Disease3263
BioCentury BCIQHPX
ClinGenHPX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3263
Chemical/Pharm GKB GenePA29441
Clinical trialHPX
Miscellaneous
canSAR (ICR)HPX (select the gene name)
DataMed IndexHPX
Probes
Litterature
PubMed79 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHPX
EVEXHPX
GoPubMedHPX
iHOPHPX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 21 15:50:06 CET 2019

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