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HRASLS2 (HRAS like suppressor 2)

Identity

Alias_symbol (synonym)FLJ20556
Other aliasPLA1/2-2
HGNC (Hugo) HRASLS2
LocusID (NCBI) 54979
Atlas_Id 50352
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 63552770 and ends at 63563383 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HRASLS2   17824
Cards
Entrez_Gene (NCBI)HRASLS2  54979  HRAS like suppressor 2
AliasesPLA1/2-2
GeneCards (Weizmann)HRASLS2
Ensembl hg19 (Hinxton)ENSG00000133328 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133328 [Gene_View]  ENSG00000133328 [Sequence]  chr11:63552770-63563383 [Contig_View]  HRASLS2 [Vega]
ICGC DataPortalENSG00000133328
TCGA cBioPortalHRASLS2
AceView (NCBI)HRASLS2
Genatlas (Paris)HRASLS2
WikiGenes54979
SOURCE (Princeton)HRASLS2
Genetics Home Reference (NIH)HRASLS2
Genomic and cartography
GoldenPath hg38 (UCSC)HRASLS2  -     chr11:63552770-63563383 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HRASLS2  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblHRASLS2 - 11q12.3 [CytoView hg19]  HRASLS2 - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBIHRASLS2 [Mapview hg19]  HRASLS2 [Mapview hg38]
OMIM613866   
Gene and transcription
Genbank (Entrez)AB453251 AK000563
RefSeq transcript (Entrez)NM_017878
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HRASLS2
Cluster EST : UnigeneHs.272805 [ NCBI ]
CGAP (NCI)Hs.272805
Alternative Splicing GalleryENSG00000133328
Gene ExpressionHRASLS2 [ NCBI-GEO ]   HRASLS2 [ EBI - ARRAY_EXPRESS ]   HRASLS2 [ SEEK ]   HRASLS2 [ MEM ]
Gene Expression Viewer (FireBrowse)HRASLS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54979
GTEX Portal (Tissue expression)HRASLS2
Human Protein AtlasENSG00000133328-HRASLS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWW9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWW9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWW9
Splice isoforms : SwissVarQ9NWW9
Catalytic activity : Enzyme2.3.1.- [ Enzyme-Expasy ]   2.3.1.-2.3.1.- [ IntEnz-EBI ]   2.3.1.- [ BRENDA ]   2.3.1.- [ KEGG ]   
PhosPhoSitePlusQ9NWW9
Domains : Interpro (EBI)LRAT-like_dom   
Domain families : Pfam (Sanger)LRAT (PF04970)   
Domain families : Pfam (NCBI)pfam04970   
Conserved Domain (NCBI)HRASLS2
DMDM Disease mutations54979
Blocks (Seattle)HRASLS2
PDB (RSDB)4DPZ   
PDB Europe4DPZ   
PDB (PDBSum)4DPZ   
PDB (IMB)4DPZ   
Structural Biology KnowledgeBase4DPZ   
SCOP (Structural Classification of Proteins)4DPZ   
CATH (Classification of proteins structures)4DPZ   
SuperfamilyQ9NWW9
Human Protein Atlas [tissue]ENSG00000133328-HRASLS2 [tissue]
Peptide AtlasQ9NWW9
HPRD13670
IPIIPI00016569   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWW9
IntAct (EBI)Q9NWW9
FunCoupENSG00000133328
BioGRIDHRASLS2
STRING (EMBL)HRASLS2
ZODIACHRASLS2
Ontologies - Pathways
QuickGOQ9NWW9
Ontology : AmiGOcytosol  integral component of membrane  lipid catabolic process  transferase activity, transferring acyl groups  hydrolase activity  phosphatidylethanolamine acyl-chain remodeling  
Ontology : EGO-EBIcytosol  integral component of membrane  lipid catabolic process  transferase activity, transferring acyl groups  hydrolase activity  phosphatidylethanolamine acyl-chain remodeling  
NDEx NetworkHRASLS2
Atlas of Cancer Signalling NetworkHRASLS2
Wikipedia pathwaysHRASLS2
Orthology - Evolution
OrthoDB54979
GeneTree (enSembl)ENSG00000133328
Phylogenetic Trees/Animal Genes : TreeFamHRASLS2
HOGENOMQ9NWW9
Homologs : HomoloGeneHRASLS2
Homology/Alignments : Family Browser (UCSC)HRASLS2
Gene fusions - Rearrangements
Fusion : QuiverHRASLS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHRASLS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HRASLS2
dbVarHRASLS2
ClinVarHRASLS2
1000_GenomesHRASLS2 
Exome Variant ServerHRASLS2
ExAC (Exome Aggregation Consortium)ENSG00000133328
GNOMAD BrowserENSG00000133328
Varsome BrowserHRASLS2
Genetic variants : HAPMAP54979
Genomic Variants (DGV)HRASLS2 [DGVbeta]
DECIPHERHRASLS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHRASLS2 
Mutations
ICGC Data PortalHRASLS2 
TCGA Data PortalHRASLS2 
Broad Tumor PortalHRASLS2
OASIS PortalHRASLS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHRASLS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHRASLS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HRASLS2
DgiDB (Drug Gene Interaction Database)HRASLS2
DoCM (Curated mutations)HRASLS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HRASLS2 (select a term)
intoGenHRASLS2
Cancer3DHRASLS2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613866   
Orphanet
DisGeNETHRASLS2
MedgenHRASLS2
Genetic Testing Registry HRASLS2
NextProtQ9NWW9 [Medical]
TSGene54979
GENETestsHRASLS2
Target ValidationHRASLS2
Huge Navigator HRASLS2 [HugePedia]
snp3D : Map Gene to Disease54979
BioCentury BCIQHRASLS2
ClinGenHRASLS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54979
Chemical/Pharm GKB GenePA29446
Clinical trialHRASLS2
Miscellaneous
canSAR (ICR)HRASLS2 (select the gene name)
DataMed IndexHRASLS2
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHRASLS2
EVEXHRASLS2
GoPubMedHRASLS2
iHOPHRASLS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 17 18:16:51 CET 2019

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