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HRASLS5 (HRAS like suppressor family member 5)

Identity

Alias_namesHRAS-like suppressor family, member 5
Alias_symbol (synonym)HRLP5
Other aliasHRSL5
RLP1
iNAT
HGNC (Hugo) HRASLS5
LocusID (NCBI) 117245
Atlas_Id 64422
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 63461404 and ends at 63491208 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RTN3 (11q13.1) / HRASLS5 (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(11;22)(q13;q13) HRASLS5/PHF21B
t(11;22)(q13;q13) HRASLS5/PHF21B


External links

Nomenclature
HGNC (Hugo)HRASLS5   24978
Cards
Entrez_Gene (NCBI)HRASLS5  117245  HRAS like suppressor family member 5
AliasesHRLP5; HRSL5; RLP1; iNAT
GeneCards (Weizmann)HRASLS5
Ensembl hg19 (Hinxton)ENSG00000168004 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168004 [Gene_View]  chr11:63461404-63491208 [Contig_View]  HRASLS5 [Vega]
ICGC DataPortalENSG00000168004
TCGA cBioPortalHRASLS5
AceView (NCBI)HRASLS5
Genatlas (Paris)HRASLS5
WikiGenes117245
SOURCE (Princeton)HRASLS5
Genetics Home Reference (NIH)HRASLS5
Genomic and cartography
GoldenPath hg38 (UCSC)HRASLS5  -     chr11:63461404-63491208 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HRASLS5  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblHRASLS5 - 11q12.3 [CytoView hg19]  HRASLS5 - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBIHRASLS5 [Mapview hg19]  HRASLS5 [Mapview hg38]
OMIM611474   
Gene and transcription
Genbank (Entrez)AB298804 AI208471 AJ416558 AK055392 AK302312
RefSeq transcript (Entrez)NM_001146728 NM_001146729 NM_054108
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HRASLS5
Cluster EST : UnigeneHs.410316 [ NCBI ]
CGAP (NCI)Hs.410316
Alternative Splicing GalleryENSG00000168004
Gene ExpressionHRASLS5 [ NCBI-GEO ]   HRASLS5 [ EBI - ARRAY_EXPRESS ]   HRASLS5 [ SEEK ]   HRASLS5 [ MEM ]
Gene Expression Viewer (FireBrowse)HRASLS5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)117245
GTEX Portal (Tissue expression)HRASLS5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96KN8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96KN8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96KN8
Splice isoforms : SwissVarQ96KN8
Catalytic activity : Enzyme2.3.1.- [ Enzyme-Expasy ]   2.3.1.-2.3.1.- [ IntEnz-EBI ]   2.3.1.- [ BRENDA ]   2.3.1.- [ KEGG ]   
PhosPhoSitePlusQ96KN8
Domains : Interpro (EBI)LRAT-like_dom   
Domain families : Pfam (Sanger)LRAT (PF04970)   
Domain families : Pfam (NCBI)pfam04970   
Conserved Domain (NCBI)HRASLS5
DMDM Disease mutations117245
Blocks (Seattle)HRASLS5
SuperfamilyQ96KN8
Human Protein AtlasENSG00000168004
Peptide AtlasQ96KN8
HPRD13672
IPIIPI00064671   IPI01009931   IPI00929215   IPI00909051   IPI00871363   IPI01014679   
Protein Interaction databases
DIP (DOE-UCLA)Q96KN8
IntAct (EBI)Q96KN8
FunCoupENSG00000168004
BioGRIDHRASLS5
STRING (EMBL)HRASLS5
ZODIACHRASLS5
Ontologies - Pathways
QuickGOQ96KN8
Ontology : AmiGON-acyltransferase activity  N-acylphosphatidylethanolamine metabolic process  
Ontology : EGO-EBIN-acyltransferase activity  N-acylphosphatidylethanolamine metabolic process  
NDEx NetworkHRASLS5
Atlas of Cancer Signalling NetworkHRASLS5
Wikipedia pathwaysHRASLS5
Orthology - Evolution
OrthoDB117245
GeneTree (enSembl)ENSG00000168004
Phylogenetic Trees/Animal Genes : TreeFamHRASLS5
HOVERGENQ96KN8
HOGENOMQ96KN8
Homologs : HomoloGeneHRASLS5
Homology/Alignments : Family Browser (UCSC)HRASLS5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHRASLS5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HRASLS5
dbVarHRASLS5
ClinVarHRASLS5
1000_GenomesHRASLS5 
Exome Variant ServerHRASLS5
ExAC (Exome Aggregation Consortium)HRASLS5 (select the gene name)
Genetic variants : HAPMAP117245
Genomic Variants (DGV)HRASLS5 [DGVbeta]
DECIPHERHRASLS5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHRASLS5 
Mutations
ICGC Data PortalHRASLS5 
TCGA Data PortalHRASLS5 
Broad Tumor PortalHRASLS5
OASIS PortalHRASLS5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHRASLS5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHRASLS5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HRASLS5
DgiDB (Drug Gene Interaction Database)HRASLS5
DoCM (Curated mutations)HRASLS5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HRASLS5 (select a term)
intoGenHRASLS5
Cancer3DHRASLS5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611474   
Orphanet
MedgenHRASLS5
Genetic Testing Registry HRASLS5
NextProtQ96KN8 [Medical]
TSGene117245
GENETestsHRASLS5
Huge Navigator HRASLS5 [HugePedia]
snp3D : Map Gene to Disease117245
BioCentury BCIQHRASLS5
ClinGenHRASLS5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD117245
Chemical/Pharm GKB GenePA142671672
Clinical trialHRASLS5
Miscellaneous
canSAR (ICR)HRASLS5 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHRASLS5
EVEXHRASLS5
GoPubMedHRASLS5
iHOPHRASLS5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 11:16:06 CEST 2017

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