Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HRH1 (histamine receptor H1)

Identity

Other namesH1-R
H1R
HH1R
hisH1
HGNC (Hugo) HRH1
LocusID (NCBI) 3269
Atlas_Id 50324
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 11294385 and ends at 11304939 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HIST1H2AM (6p22.1) / HRH1 (3p25.3)HRH1 (3p25.3) / MRPL51 (12p13.31)PACSIN2 (22q13.2) / HRH1 (3p25.3)
RNF166 (16q24.3) / HRH1 (3p25.3)STAG1 (3q22.3) / HRH1 (3p25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HRH1   5182
Cards
Entrez_Gene (NCBI)HRH1  3269  histamine receptor H1
AliasesH1-R; H1R; HH1R; hisH1
GeneCards (Weizmann)HRH1
Ensembl hg19 (Hinxton)ENSG00000196639 [Gene_View]  chr3:11294385-11304939 [Contig_View]  HRH1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000196639 [Gene_View]  chr3:11294385-11304939 [Contig_View]  HRH1 [Vega]
ICGC DataPortalENSG00000196639
TCGA cBioPortalHRH1
AceView (NCBI)HRH1
Genatlas (Paris)HRH1
WikiGenes3269
SOURCE (Princeton)HRH1
Genomic and cartography
GoldenPath hg19 (UCSC)HRH1  -     chr3:11294385-11304939 +  3p25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HRH1  -     3p25.3   [Description]    (hg38-Dec_2013)
EnsemblHRH1 - 3p25.3 [CytoView hg19]  HRH1 - 3p25.3 [CytoView hg38]
Mapping of homologs : NCBIHRH1 [Mapview hg19]  HRH1 [Mapview hg38]
OMIM600167   
Gene and transcription
Genbank (Entrez)AF026261 AK289412 AK292157 AK312879 AY136743
RefSeq transcript (Entrez)NM_000861 NM_001098211 NM_001098212 NM_001098213
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)HRH1
Cluster EST : UnigeneHs.1570 [ NCBI ]
CGAP (NCI)Hs.1570
Alternative Splicing GalleryENSG00000196639
Gene ExpressionHRH1 [ NCBI-GEO ]   HRH1 [ EBI - ARRAY_EXPRESS ]   HRH1 [ SEEK ]   HRH1 [ MEM ]
Gene Expression Viewer (FireBrowse)HRH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3269
GTEX Portal (Tissue expression)HRH1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35367 (Uniprot)
NextProtP35367  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP35367
Splice isoforms : SwissVarP35367 (Swissvar)
PhosPhoSitePlusP35367
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Histamine_H1_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
DMDM Disease mutations3269
Blocks (Seattle)HRH1
PDB (SRS)3RZE   
PDB (PDBSum)3RZE   
PDB (IMB)3RZE   
PDB (RSDB)3RZE   
Structural Biology KnowledgeBase3RZE   
SCOP (Structural Classification of Proteins)3RZE   
CATH (Classification of proteins structures)3RZE   
SuperfamilyP35367
Human Protein AtlasENSG00000196639
Peptide AtlasP35367
HPRD02544
IPIIPI00018147   IPI00924526   
Protein Interaction databases
DIP (DOE-UCLA)P35367
IntAct (EBI)P35367
FunCoupENSG00000196639
BioGRIDHRH1
STRING (EMBL)HRH1
ZODIACHRH1
Ontologies - Pathways
QuickGOP35367
Ontology : AmiGOG-protein coupled receptor activity  histamine receptor activity  nucleoplasm  cytoplasm  plasma membrane  plasma membrane  integral component of plasma membrane  inflammatory response  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  memory  visual learning  regulation of vasoconstriction  positive regulation of inositol trisphosphate biosynthetic process  regulation of vascular permeability  positive regulation of vasoconstriction  inositol phosphate-mediated signaling  regulation of synaptic plasticity  eosinophil chemotaxis  modulation of synaptic transmission  cellular response to histamine  
Ontology : EGO-EBIG-protein coupled receptor activity  histamine receptor activity  nucleoplasm  cytoplasm  plasma membrane  plasma membrane  integral component of plasma membrane  inflammatory response  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  memory  visual learning  regulation of vasoconstriction  positive regulation of inositol trisphosphate biosynthetic process  regulation of vascular permeability  positive regulation of vasoconstriction  inositol phosphate-mediated signaling  regulation of synaptic plasticity  eosinophil chemotaxis  modulation of synaptic transmission  cellular response to histamine  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction   
NDEx Network
Atlas of Cancer Signalling NetworkHRH1
Wikipedia pathwaysHRH1
Orthology - Evolution
OrthoDB3269
GeneTree (enSembl)ENSG00000196639
Phylogenetic Trees/Animal Genes : TreeFamHRH1
Homologs : HomoloGeneHRH1
Homology/Alignments : Family Browser (UCSC)HRH1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerHRH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HRH1
dbVarHRH1
ClinVarHRH1
1000_GenomesHRH1 
Exome Variant ServerHRH1
ExAC (Exome Aggregation Consortium)HRH1 (select the gene name)
Genetic variants : HAPMAP3269
Genomic Variants (DGV)HRH1 [DGVbeta]
Mutations
ICGC Data PortalHRH1 
TCGA Data PortalHRH1 
Broad Tumor PortalHRH1
OASIS PortalHRH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHRH1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HRH1
DgiDB (Drug Gene Interaction Database)HRH1
DoCM (Curated mutations)HRH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HRH1 (select a term)
intoGenHRH1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:11294385-11304939  ENSG00000196639
CONAN: Copy Number AnalysisHRH1 
Mutations and Diseases : HGMDHRH1
OMIM600167   
MedgenHRH1
Genetic Testing Registry HRH1
NextProtP35367 [Medical]
TSGene3269
GENETestsHRH1
Huge Navigator HRH1 [HugePedia]
snp3D : Map Gene to Disease3269
BioCentury BCIQHRH1
ClinGenHRH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3269
Chemical/Pharm GKB GenePA29456
Clinical trialHRH1
Miscellaneous
canSAR (ICR)HRH1 (select the gene name)
Probes
Litterature
PubMed92 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHRH1
EVEXHRH1
GoPubMedHRH1
iHOPHRH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 9 19:04:02 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.