Atlas of Genetics and Cytogenetics in Oncology and Haematology

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HRK (harakiri, BCL2 interacting protein (contains only BH3 domain))

Identity

Other namesDP5
HARAKIRI
HGNC (Hugo) HRK
Location 12q24.22
Location_base_pair Starts at 115783410 and ends at 115803615 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)HRK   5185
Entrez_Gene (NCBI)HRK  8739  harakiri, BCL2 interacting protein (contains only BH3 domain)
Cards
GeneCards (Weizmann)HRK
Ensembl (Hinxton)ENSG00000135116 [Gene_View]  HRK [Vega]
AceView (NCBI)HRK
Genatlas (Paris)HRK
euGene (Indiana)8739
SOURCE (Stanford)NM_003806
Gene Expression (Array Express) ENSG00000135116
Genomic and cartography
GoldenPath (UCSC)HRK  -  12q24.22   chr12:115783410-115803615 -  12q24.22   [Description]    (hg18-March_2006)
EnsemblHRK - 12q24.22 [CytoView]
Mapping of homologs : NCBIHRK [Mapview]
OMIM603447   
Gene and transcription
Gene : Genbank (Entrez)BC111923 D83699 U76376
Reference sequence (RefSeq transcript) :SRSNM_003806
Reference transcript : EntrezNM_003806
RefSeq genomic : SRSAC_000055 AC_000144 NC_000012 NT_009775 NW_001838063 NW_925395
RefSeq genomic : EntrezAC_000055 AC_000144 NC_000012 NT_009775 NW_001838063 NW_925395
Consensus coding sequences : CCDS NCBIHRK
Cluster EST : UnigeneHs.87247 [ SRS ] Hs.87247 [ NCBI ]
Alternative Splicing : Fast-db (Paris)13845
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtO00198 (SRS) O00198 (Expasy) O00198 (Uniprot)
With graphics : InterProO00198
Splice isoforms : VarSplice FASTAO00198(VarSplice FASTA)
Domaine pattern : Prosite (SRS)BH3 (PS01259)   
Domain pattern : Prosite (Expaxy)BH3 (PS01259)   
Domains : Interpro (SRS)Apoptosis_activator_harakiri    Bcl2_BH3_motif_CS   
Domains : Interpro (EBI)Apoptosis_activator_harakiri    Bcl2_BH3_motif_CS   
Related proteins : CluSTrO00198
Domain families : Pfam SRS
Domain families : Pfam Sanger
Domain families : Pfam NCBI
Blocks (Seattle)O00198
Crystal structure of protein : PDB SRS
Crystal structure of protein : PDBSum
Crystal structure of protein : IMB
Crystal structure of protein : PDB RSDB
HPRD04581
Protein Interaction databases
DIP (DOE-UCLA)O00198
IntAct (EBI)O00198
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIHRK
SNP : GeneSNP UtahHRK
SNP : HGBaseHRK
Genetic variants : HAPMAPHRK
Somatic Mutations in Cancer : COSMICHRK 
Mutations and Diseases : HGMDHRK
Hereditary diseases : OMIM603447   
Hereditary diseases : GENETests603447   
Diseases : Genetic AssociationHRK
General knowledge
Homologs : HomoloGeneHRK
Homology/Alignments : Family Browser UCSCHRK
Phylogenetic Trees/Animal Genes : TreeFamHRK
Chemical/Protein Interactions : CTD8739
Keywords Ontology : AmiGOprotein binding  induction of apoptosis  negative regulation of survival gene product expression  regulation of apoptosis  positive regulation of neuron apoptosis  cellular response to potassium ion starvation  
Keywords Ontology : EGO-EBIprotein binding  induction of apoptosis  negative regulation of survival gene product expression  regulation of apoptosis  positive regulation of neuron apoptosis  cellular response to potassium ion starvation  
Pathways : BIOCARTA
Pathways : KEGG
Other databases
Probes
Probes : ImagenesHRK Related clones (RZPD - Berlin)
Literature
PubMed19 Pubmed reference(s) in Entrez
PubGeneHRK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:34:10 CET 2010
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