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HS2ST1 (heparan sulfate 2-O-sulfotransferase 1)

Identity

Alias_symbol (synonym)KIAA0448
Other aliasdJ604K5.2
HGNC (Hugo) HS2ST1
LocusID (NCBI) 9653
Atlas_Id 64427
Location 1p22.3  [Link to chromosome band 1p22]
Location_base_pair Starts at 86914652 and ends at 87098442 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CENPF (1q41) / HS2ST1 (1p22.3)HS2ST1 (1p22.3) / GBP6 (1p22.2)HS2ST1 (1p22.3) / KCNJ2-AS1 (17q24.3)
HS2ST1 (1p22.3) / NXNL2 (9q22.1)HS2ST1 (1p22.3) / PCGF3 (4p16.3)HS2ST1 (1p22.3) / PRDX1 (1p34.1)
HS2ST1 (1p22.3) / RUNX2 (6p21.1)HS2ST1 (1p22.3) / SSX2IP (1p22.3)MICALCL (11p15.3) / HS2ST1 (1p22.3)
UBA2 (19q13.11) / HS2ST1 (1p22.3)HS2ST1 PRDX1HS2ST1 GBP6
HS2ST1 NXNL2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HS2ST1   5193
Cards
Entrez_Gene (NCBI)HS2ST1  9653  heparan sulfate 2-O-sulfotransferase 1
AliasesdJ604K5.2
GeneCards (Weizmann)HS2ST1
Ensembl hg19 (Hinxton)ENSG00000153936 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000153936 [Gene_View]  chr1:86914652-87098442 [Contig_View]  HS2ST1 [Vega]
ICGC DataPortalENSG00000153936
TCGA cBioPortalHS2ST1
AceView (NCBI)HS2ST1
Genatlas (Paris)HS2ST1
WikiGenes9653
SOURCE (Princeton)HS2ST1
Genetics Home Reference (NIH)HS2ST1
Genomic and cartography
GoldenPath hg38 (UCSC)HS2ST1  -     chr1:86914652-87098442 +  1p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HS2ST1  -     1p22.3   [Description]    (hg19-Feb_2009)
EnsemblHS2ST1 - 1p22.3 [CytoView hg19]  HS2ST1 - 1p22.3 [CytoView hg38]
Mapping of homologs : NCBIHS2ST1 [Mapview hg19]  HS2ST1 [Mapview hg38]
OMIM604844   
Gene and transcription
Genbank (Entrez)AB007917 AB024568 AF086247 AK023260 BC025384
RefSeq transcript (Entrez)NM_001134492 NM_012262
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HS2ST1
Cluster EST : UnigeneHs.743280 [ NCBI ]
CGAP (NCI)Hs.743280
Alternative Splicing GalleryENSG00000153936
Gene ExpressionHS2ST1 [ NCBI-GEO ]   HS2ST1 [ EBI - ARRAY_EXPRESS ]   HS2ST1 [ SEEK ]   HS2ST1 [ MEM ]
Gene Expression Viewer (FireBrowse)HS2ST1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9653
GTEX Portal (Tissue expression)HS2ST1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7LGA3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7LGA3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7LGA3
Splice isoforms : SwissVarQ7LGA3
PhosPhoSitePlusQ7LGA3
Domains : Interpro (EBI)Heparan_SO4_2-O-STrfase    P-loop_NTPase    Sulfotransferase   
Domain families : Pfam (Sanger)Sulfotransfer_2 (PF03567)   
Domain families : Pfam (NCBI)pfam03567   
Conserved Domain (NCBI)HS2ST1
DMDM Disease mutations9653
Blocks (Seattle)HS2ST1
SuperfamilyQ7LGA3
Human Protein AtlasENSG00000153936
Peptide AtlasQ7LGA3
HPRD09215
IPIIPI00549891   IPI00552241   IPI00040900   
Protein Interaction databases
DIP (DOE-UCLA)Q7LGA3
IntAct (EBI)Q7LGA3
FunCoupENSG00000153936
BioGRIDHS2ST1
STRING (EMBL)HS2ST1
ZODIACHS2ST1
Ontologies - Pathways
QuickGOQ7LGA3
Ontology : AmiGOGolgi membrane  heparan sulfate 2-O-sulfotransferase activity  glycosaminoglycan biosynthetic process  membrane  integral component of membrane  
Ontology : EGO-EBIGolgi membrane  heparan sulfate 2-O-sulfotransferase activity  glycosaminoglycan biosynthetic process  membrane  integral component of membrane  
Pathways : KEGGGlycosaminoglycan biosynthesis - heparan sulfate / heparin   
NDEx NetworkHS2ST1
Atlas of Cancer Signalling NetworkHS2ST1
Wikipedia pathwaysHS2ST1
Orthology - Evolution
OrthoDB9653
GeneTree (enSembl)ENSG00000153936
Phylogenetic Trees/Animal Genes : TreeFamHS2ST1
HOVERGENQ7LGA3
HOGENOMQ7LGA3
Homologs : HomoloGeneHS2ST1
Homology/Alignments : Family Browser (UCSC)HS2ST1
Gene fusions - Rearrangements
Fusion: TCGAHS2ST1 PRDX1
Fusion: TCGAHS2ST1 GBP6
Fusion: TCGAHS2ST1 NXNL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHS2ST1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HS2ST1
dbVarHS2ST1
ClinVarHS2ST1
1000_GenomesHS2ST1 
Exome Variant ServerHS2ST1
ExAC (Exome Aggregation Consortium)HS2ST1 (select the gene name)
Genetic variants : HAPMAP9653
Genomic Variants (DGV)HS2ST1 [DGVbeta]
DECIPHERHS2ST1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHS2ST1 
Mutations
ICGC Data PortalHS2ST1 
TCGA Data PortalHS2ST1 
Broad Tumor PortalHS2ST1
OASIS PortalHS2ST1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHS2ST1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHS2ST1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HS2ST1
DgiDB (Drug Gene Interaction Database)HS2ST1
DoCM (Curated mutations)HS2ST1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HS2ST1 (select a term)
intoGenHS2ST1
Cancer3DHS2ST1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604844   
Orphanet
MedgenHS2ST1
Genetic Testing Registry HS2ST1
NextProtQ7LGA3 [Medical]
TSGene9653
GENETestsHS2ST1
Huge Navigator HS2ST1 [HugePedia]
snp3D : Map Gene to Disease9653
BioCentury BCIQHS2ST1
ClinGenHS2ST1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9653
Chemical/Pharm GKB GenePA29466
Clinical trialHS2ST1
Miscellaneous
canSAR (ICR)HS2ST1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHS2ST1
EVEXHS2ST1
GoPubMedHS2ST1
iHOPHS2ST1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 11:16:08 CEST 2017

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