Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1)

Identity

Alias_namesheparan sulfate (glucosamine) 3-O-sulfotransferase 1
Alias_symbol (synonym)3OST1
Other alias3OST
HGNC (Hugo) HS3ST1
LocusID (NCBI) 9957
Atlas_Id 54369
Location 4p15.33  [Link to chromosome band 4p15]
Location_base_pair Starts at 11399988 and ends at 11430537 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANKRD17 (4q13.3) / HS3ST1 (4p15.33)HS3ST1 (4p15.33) / CNTN5 (11q22.1)HS3ST1 (4p15.33) / EXD2 (14q24.1)
HS3ST1 4p15.33 / CNTN5 11q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HS3ST1   5194
Cards
Entrez_Gene (NCBI)HS3ST1  9957  heparan sulfate-glucosamine 3-sulfotransferase 1
Aliases3OST; 3OST1
GeneCards (Weizmann)HS3ST1
Ensembl hg19 (Hinxton)ENSG00000002587 [Gene_View]  chr4:11399988-11430537 [Contig_View]  HS3ST1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000002587 [Gene_View]  chr4:11399988-11430537 [Contig_View]  HS3ST1 [Vega]
ICGC DataPortalENSG00000002587
TCGA cBioPortalHS3ST1
AceView (NCBI)HS3ST1
Genatlas (Paris)HS3ST1
WikiGenes9957
SOURCE (Princeton)HS3ST1
Genetics Home Reference (NIH)HS3ST1
Genomic and cartography
GoldenPath hg19 (UCSC)HS3ST1  -     chr4:11399988-11430537 -  4p15.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HS3ST1  -     4p15.33   [Description]    (hg38-Dec_2013)
EnsemblHS3ST1 - 4p15.33 [CytoView hg19]  HS3ST1 - 4p15.33 [CytoView hg38]
Mapping of homologs : NCBIHS3ST1 [Mapview hg19]  HS3ST1 [Mapview hg38]
OMIM603244   
Gene and transcription
Genbank (Entrez)AA825270 AF019386 AI478981 AK096823 BC025735
RefSeq transcript (Entrez)NM_005114
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_006316 NW_004929315
Consensus coding sequences : CCDS (NCBI)HS3ST1
Cluster EST : UnigeneHs.605349 [ NCBI ]
CGAP (NCI)Hs.605349
Alternative Splicing GalleryENSG00000002587
Gene ExpressionHS3ST1 [ NCBI-GEO ]   HS3ST1 [ EBI - ARRAY_EXPRESS ]   HS3ST1 [ SEEK ]   HS3ST1 [ MEM ]
Gene Expression Viewer (FireBrowse)HS3ST1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9957
GTEX Portal (Tissue expression)HS3ST1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14792   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14792  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14792
Splice isoforms : SwissVarO14792
Catalytic activity : Enzyme2.8.2.23 [ Enzyme-Expasy ]   2.8.2.232.8.2.23 [ IntEnz-EBI ]   2.8.2.23 [ BRENDA ]   2.8.2.23 [ KEGG ]   
PhosPhoSitePlusO14792
Domains : Interpro (EBI)P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)HS3ST1
DMDM Disease mutations9957
Blocks (Seattle)HS3ST1
PDB (SRS)1ZRH   
PDB (PDBSum)1ZRH   
PDB (IMB)1ZRH   
PDB (RSDB)1ZRH   
Structural Biology KnowledgeBase1ZRH   
SCOP (Structural Classification of Proteins)1ZRH   
CATH (Classification of proteins structures)1ZRH   
SuperfamilyO14792
Human Protein AtlasENSG00000002587
Peptide AtlasO14792
HPRD04455
IPIIPI00021377   IPI00966867   
Protein Interaction databases
DIP (DOE-UCLA)O14792
IntAct (EBI)O14792
FunCoupENSG00000002587
BioGRIDHS3ST1
STRING (EMBL)HS3ST1
ZODIACHS3ST1
Ontologies - Pathways
QuickGOO14792
Ontology : AmiGOGolgi lumen  glycosaminoglycan biosynthetic process  sulfotransferase activity  [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  integral component of membrane  
Ontology : EGO-EBIGolgi lumen  glycosaminoglycan biosynthetic process  sulfotransferase activity  [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  integral component of membrane  
Pathways : KEGGGlycosaminoglycan biosynthesis - heparan sulfate / heparin   
NDEx NetworkHS3ST1
Atlas of Cancer Signalling NetworkHS3ST1
Wikipedia pathwaysHS3ST1
Orthology - Evolution
OrthoDB9957
GeneTree (enSembl)ENSG00000002587
Phylogenetic Trees/Animal Genes : TreeFamHS3ST1
HOVERGENO14792
HOGENOMO14792
Homologs : HomoloGeneHS3ST1
Homology/Alignments : Family Browser (UCSC)HS3ST1
Gene fusions - Rearrangements
Fusion : MitelmanANKRD17/HS3ST1 [4q13.3/4p15.33]  [t(4;4)(p15;q13)]  
Fusion : MitelmanHS3ST1/CNTN5 [4p15.33/11q22.1]  [t(4;11)(p15;q22)]  
Fusion: TCGAHS3ST1 4p15.33 CNTN5 11q22.1 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHS3ST1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HS3ST1
dbVarHS3ST1
ClinVarHS3ST1
1000_GenomesHS3ST1 
Exome Variant ServerHS3ST1
ExAC (Exome Aggregation Consortium)HS3ST1 (select the gene name)
Genetic variants : HAPMAP9957
Genomic Variants (DGV)HS3ST1 [DGVbeta]
DECIPHER (Syndromes)4:11399988-11430537  ENSG00000002587
CONAN: Copy Number AnalysisHS3ST1 
Mutations
ICGC Data PortalHS3ST1 
TCGA Data PortalHS3ST1 
Broad Tumor PortalHS3ST1
OASIS PortalHS3ST1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHS3ST1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHS3ST1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HS3ST1
DgiDB (Drug Gene Interaction Database)HS3ST1
DoCM (Curated mutations)HS3ST1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HS3ST1 (select a term)
intoGenHS3ST1
Cancer3DHS3ST1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603244   
Orphanet
MedgenHS3ST1
Genetic Testing Registry HS3ST1
NextProtO14792 [Medical]
TSGene9957
GENETestsHS3ST1
Huge Navigator HS3ST1 [HugePedia]
snp3D : Map Gene to Disease9957
BioCentury BCIQHS3ST1
ClinGenHS3ST1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9957
Chemical/Pharm GKB GenePA29467
Clinical trialHS3ST1
Miscellaneous
canSAR (ICR)HS3ST1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHS3ST1
EVEXHS3ST1
GoPubMedHS3ST1
iHOPHS3ST1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:09:46 CET 2017

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