HS3ST3B1 (heparan sulfate-glucosamine 3-sulfotransferase 3B1)

2012-02-01  

Identity

HGNC
LOCATION
17p12
LOCUSID
ALIAS
3-OST-3B,3OST3B1,h3-OST-3B
FUSION GENES

Other Information

Locus ID:

NCBI: 9953
MIM: 604058
HGNC: 5198
Ensembl: ENSG00000125430

Variants:

dbSNP: 9953
ClinVar: 9953
TCGA: ENSG00000125430
COSMIC: HS3ST3B1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125430ENST00000360954Q9Y662
ENSG00000125430ENST00000466596Q9Y662

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGko00534
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGhsa00534
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Heparan sulfate/heparin (HS-GAG) metabolismREACTOMER-HSA-1638091
HS-GAG biosynthesisREACTOMER-HSA-2022928

References

Pubmed IDYearTitleCitations
241275552013Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses.18
207053112010Heparin sulphate D-glucosaminyl 3-O-sulfotransferase 3B1 plays a role in HBV replication.10
217094402011Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer.9
224755332012Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.6
295169542018Heparan sulfate D-glucosamine 3-O-sulfotransferase 3B1 is a novel regulator of transforming growth factor-beta-mediated epithelial-to-mesenchymal transition and regulated by miR-218 in nonsmall cell lung cancer.4
207973172010Analysis of copy number variation in 8,842 Korean individuals reveals 39 genes associated with hepatic biomarkers AST and ALT.2
297182952018Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia.1

Citation

Dessen P

HS3ST3B1 (heparan sulfate-glucosamine 3-sulfotransferase 3B1)

Atlas Genet Cytogenet Oncol Haematol. 2012-02-01

Online version: http://atlasgeneticsoncology.org/gene/52598/hs3st3b1