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HS3ST4 (heparan sulfate (glucosamine) 3-O-sulfotransferase 4)

Identity

Alias_namesheparan sulfate (glucosamine) 3-O-sulfotransferase 4
Alias_symbol (synonym)3OST4
Other alias3-OST-4
30ST4
h3-OST-4
HGNC (Hugo) HS3ST4
LocusID (NCBI) 9951
Atlas_Id 64429
Location 16p12.1  [Link to chromosome band 16p12]
Location_base_pair Starts at 25703347 and ends at 26149009 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADGRB2 (1p35.2) / HS3ST4 (16p12.1)CDK14 (7q21.13) / HS3ST4 (16p12.1)HS3ST4 (16p12.1) / ATP5G2 (12q13.13)
HS3ST4 (16p12.1) / FEN1 (11q12.2)NFATC2IP (16p11.2) / HS3ST4 (16p12.1)NFATC2IP HS3ST4
BAI2 HS3ST4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HS3ST4   5200
Cards
Entrez_Gene (NCBI)HS3ST4  9951  heparan sulfate (glucosamine) 3-O-sulfotransferase 4
Aliases3-OST-4; 30ST4; 3OST4; h3-OST-4
GeneCards (Weizmann)HS3ST4
Ensembl hg19 (Hinxton)ENSG00000182601 [Gene_View]  chr16:25703347-26149009 [Contig_View]  HS3ST4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000182601 [Gene_View]  chr16:25703347-26149009 [Contig_View]  HS3ST4 [Vega]
ICGC DataPortalENSG00000182601
TCGA cBioPortalHS3ST4
AceView (NCBI)HS3ST4
Genatlas (Paris)HS3ST4
WikiGenes9951
SOURCE (Princeton)HS3ST4
Genetics Home Reference (NIH)HS3ST4
Genomic and cartography
GoldenPath hg19 (UCSC)HS3ST4  -     chr16:25703347-26149009 +  16p12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HS3ST4  -     16p12.1   [Description]    (hg38-Dec_2013)
EnsemblHS3ST4 - 16p12.1 [CytoView hg19]  HS3ST4 - 16p12.1 [CytoView hg38]
Mapping of homologs : NCBIHS3ST4 [Mapview hg19]  HS3ST4 [Mapview hg38]
OMIM604059   
Gene and transcription
Genbank (Entrez)AF105378 AL834283 BC156387 BC157117 EF063601
RefSeq transcript (Entrez)NM_006040
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_187260 NW_004929400
Consensus coding sequences : CCDS (NCBI)HS3ST4
Cluster EST : UnigeneHs.655275 [ NCBI ]
CGAP (NCI)Hs.655275
Alternative Splicing GalleryENSG00000182601
Gene ExpressionHS3ST4 [ NCBI-GEO ]   HS3ST4 [ EBI - ARRAY_EXPRESS ]   HS3ST4 [ SEEK ]   HS3ST4 [ MEM ]
Gene Expression Viewer (FireBrowse)HS3ST4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9951
GTEX Portal (Tissue expression)HS3ST4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y661   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y661  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y661
Splice isoforms : SwissVarQ9Y661
Catalytic activity : Enzyme2.8.2.23 [ Enzyme-Expasy ]   2.8.2.232.8.2.23 [ IntEnz-EBI ]   2.8.2.23 [ BRENDA ]   2.8.2.23 [ KEGG ]   
PhosPhoSitePlusQ9Y661
Domains : Interpro (EBI)P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)HS3ST4
DMDM Disease mutations9951
Blocks (Seattle)HS3ST4
SuperfamilyQ9Y661
Human Protein AtlasENSG00000182601
Peptide AtlasQ9Y661
HPRD04960
IPIIPI00418602   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y661
IntAct (EBI)Q9Y661
FunCoupENSG00000182601
BioGRIDHS3ST4
STRING (EMBL)HS3ST4
ZODIACHS3ST4
Ontologies - Pathways
QuickGOQ9Y661
Ontology : AmiGOGolgi membrane  [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  integral component of membrane  heparan sulfate proteoglycan metabolic process  
Ontology : EGO-EBIGolgi membrane  [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  integral component of membrane  heparan sulfate proteoglycan metabolic process  
NDEx NetworkHS3ST4
Atlas of Cancer Signalling NetworkHS3ST4
Wikipedia pathwaysHS3ST4
Orthology - Evolution
OrthoDB9951
GeneTree (enSembl)ENSG00000182601
Phylogenetic Trees/Animal Genes : TreeFamHS3ST4
HOVERGENQ9Y661
HOGENOMQ9Y661
Homologs : HomoloGeneHS3ST4
Homology/Alignments : Family Browser (UCSC)HS3ST4
Gene fusions - Rearrangements
Fusion: TCGANFATC2IP HS3ST4
Fusion: TCGABAI2 HS3ST4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHS3ST4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HS3ST4
dbVarHS3ST4
ClinVarHS3ST4
1000_GenomesHS3ST4 
Exome Variant ServerHS3ST4
ExAC (Exome Aggregation Consortium)HS3ST4 (select the gene name)
Genetic variants : HAPMAP9951
Genomic Variants (DGV)HS3ST4 [DGVbeta]
DECIPHER (Syndromes)16:25703347-26149009  ENSG00000182601
CONAN: Copy Number AnalysisHS3ST4 
Mutations
ICGC Data PortalHS3ST4 
TCGA Data PortalHS3ST4 
Broad Tumor PortalHS3ST4
OASIS PortalHS3ST4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHS3ST4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHS3ST4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HS3ST4
DgiDB (Drug Gene Interaction Database)HS3ST4
DoCM (Curated mutations)HS3ST4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HS3ST4 (select a term)
intoGenHS3ST4
Cancer3DHS3ST4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604059   
Orphanet
MedgenHS3ST4
Genetic Testing Registry HS3ST4
NextProtQ9Y661 [Medical]
TSGene9951
GENETestsHS3ST4
Huge Navigator HS3ST4 [HugePedia]
snp3D : Map Gene to Disease9951
BioCentury BCIQHS3ST4
ClinGenHS3ST4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9951
Chemical/Pharm GKB GenePA29473
Clinical trialHS3ST4
Miscellaneous
canSAR (ICR)HS3ST4 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHS3ST4
EVEXHS3ST4
GoPubMedHS3ST4
iHOPHS3ST4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:08:14 CET 2017

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