Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HS3ST5 (heparan sulfate-glucosamine 3-sulfotransferase 5)

Identity

Alias_namesheparan sulfate (glucosamine) 3-O-sulfotransferase 5
Alias_symbol (synonym)3-OST-5
Other alias3OST5
HS3OST5
NBLA04021
HGNC (Hugo) HS3ST5
LocusID (NCBI) 222537
Atlas_Id 64430
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 114055586 and ends at 114062877 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
VPS53 (17p13.3) / HS3ST5 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HS3ST5   19419
Cards
Entrez_Gene (NCBI)HS3ST5  222537  heparan sulfate-glucosamine 3-sulfotransferase 5
Aliases3-OST-5; 3OST5; HS3OST5; NBLA04021
GeneCards (Weizmann)HS3ST5
Ensembl hg19 (Hinxton)ENSG00000249853 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000249853 [Gene_View]  chr6:114055586-114062877 [Contig_View]  HS3ST5 [Vega]
ICGC DataPortalENSG00000249853
TCGA cBioPortalHS3ST5
AceView (NCBI)HS3ST5
Genatlas (Paris)HS3ST5
WikiGenes222537
SOURCE (Princeton)HS3ST5
Genetics Home Reference (NIH)HS3ST5
Genomic and cartography
GoldenPath hg38 (UCSC)HS3ST5  -     chr6:114055586-114062877 -  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HS3ST5  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblHS3ST5 - 6q21 [CytoView hg19]  HS3ST5 - 6q21 [CytoView hg38]
Mapping of homologs : NCBIHS3ST5 [Mapview hg19]  HS3ST5 [Mapview hg38]
OMIM609407   
Gene and transcription
Genbank (Entrez)AB074164 AF503292 AK091074 AK126930 AK289907
RefSeq transcript (Entrez)NM_153612
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HS3ST5
Cluster EST : UnigeneHs.645477 [ NCBI ]
CGAP (NCI)Hs.645477
Alternative Splicing GalleryENSG00000249853
Gene ExpressionHS3ST5 [ NCBI-GEO ]   HS3ST5 [ EBI - ARRAY_EXPRESS ]   HS3ST5 [ SEEK ]   HS3ST5 [ MEM ]
Gene Expression Viewer (FireBrowse)HS3ST5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222537
GTEX Portal (Tissue expression)HS3ST5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZT8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZT8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZT8
Splice isoforms : SwissVarQ8IZT8
Catalytic activity : Enzyme2.8.2.23 [ Enzyme-Expasy ]   2.8.2.232.8.2.23 [ IntEnz-EBI ]   2.8.2.23 [ BRENDA ]   2.8.2.23 [ KEGG ]   
PhosPhoSitePlusQ8IZT8
Domains : Interpro (EBI)P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)HS3ST5
DMDM Disease mutations222537
Blocks (Seattle)HS3ST5
PDB (SRS)3BD9   
PDB (PDBSum)3BD9   
PDB (IMB)3BD9   
PDB (RSDB)3BD9   
Structural Biology KnowledgeBase3BD9   
SCOP (Structural Classification of Proteins)3BD9   
CATH (Classification of proteins structures)3BD9   
SuperfamilyQ8IZT8
Human Protein AtlasENSG00000249853
Peptide AtlasQ8IZT8
HPRD13674
IPIIPI00218071   IPI00654554   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZT8
IntAct (EBI)Q8IZT8
FunCoupENSG00000249853
BioGRIDHS3ST5
STRING (EMBL)HS3ST5
ZODIACHS3ST5
Ontologies - Pathways
QuickGOQ8IZT8
Ontology : AmiGOGolgi membrane  protein binding  glycosaminoglycan biosynthetic process  protein sulfation  [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  heparan sulfate proteoglycan biosynthetic process, enzymatic modification  integral component of membrane  regulation of viral entry into host cell  3'-phosphoadenosine 5'-phosphosulfate binding  negative regulation of coagulation  
Ontology : EGO-EBIGolgi membrane  protein binding  glycosaminoglycan biosynthetic process  protein sulfation  [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  heparan sulfate proteoglycan biosynthetic process, enzymatic modification  integral component of membrane  regulation of viral entry into host cell  3'-phosphoadenosine 5'-phosphosulfate binding  negative regulation of coagulation  
Pathways : KEGGGlycosaminoglycan biosynthesis - heparan sulfate / heparin   
NDEx NetworkHS3ST5
Atlas of Cancer Signalling NetworkHS3ST5
Wikipedia pathwaysHS3ST5
Orthology - Evolution
OrthoDB222537
GeneTree (enSembl)ENSG00000249853
Phylogenetic Trees/Animal Genes : TreeFamHS3ST5
HOVERGENQ8IZT8
HOGENOMQ8IZT8
Homologs : HomoloGeneHS3ST5
Homology/Alignments : Family Browser (UCSC)HS3ST5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHS3ST5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HS3ST5
dbVarHS3ST5
ClinVarHS3ST5
1000_GenomesHS3ST5 
Exome Variant ServerHS3ST5
ExAC (Exome Aggregation Consortium)HS3ST5 (select the gene name)
Genetic variants : HAPMAP222537
Genomic Variants (DGV)HS3ST5 [DGVbeta]
DECIPHERHS3ST5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHS3ST5 
Mutations
ICGC Data PortalHS3ST5 
TCGA Data PortalHS3ST5 
Broad Tumor PortalHS3ST5
OASIS PortalHS3ST5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHS3ST5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHS3ST5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HS3ST5
DgiDB (Drug Gene Interaction Database)HS3ST5
DoCM (Curated mutations)HS3ST5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HS3ST5 (select a term)
intoGenHS3ST5
Cancer3DHS3ST5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609407   
Orphanet
MedgenHS3ST5
Genetic Testing Registry HS3ST5
NextProtQ8IZT8 [Medical]
TSGene222537
GENETestsHS3ST5
Target ValidationHS3ST5
Huge Navigator HS3ST5 [HugePedia]
snp3D : Map Gene to Disease222537
BioCentury BCIQHS3ST5
ClinGenHS3ST5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD222537
Chemical/Pharm GKB GenePA164741639
Clinical trialHS3ST5
Miscellaneous
canSAR (ICR)HS3ST5 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHS3ST5
EVEXHS3ST5
GoPubMedHS3ST5
iHOPHS3ST5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:10:47 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.