Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HS6ST2 (heparan sulfate 6-O-sulfotransferase 2)

Identity

Other alias-
HGNC (Hugo) HS6ST2
LocusID (NCBI) 90161
Atlas_Id 52350
Location Xq26.2  [Link to chromosome band Xq26]
Location_base_pair Starts at 132626010 and ends at 132961395 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HS6ST2 (Xq26.2) / GPC3 (Xq26.2)HS6ST2 (Xq26.2) / NDUFB2 (7q34)HS6ST2 (Xq26.2) / NPFFR2 (4q13.3)
KIAA1755 (20q11.23) / HS6ST2 (Xq26.2)PDXDC1 (16p13.11) / HS6ST2 (Xq26.2)TTC28 (22q12.1) / HS6ST2 (Xq26.2)
HS6ST2 Xq26.2 / NPFFR2 4q13.3KIAA1755 20q11.23 / HS6ST2 Xq26.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HS6ST2   19133
Cards
Entrez_Gene (NCBI)HS6ST2  90161  heparan sulfate 6-O-sulfotransferase 2
Aliases
GeneCards (Weizmann)HS6ST2
Ensembl hg19 (Hinxton)ENSG00000171004 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171004 [Gene_View]  chrX:132626010-132961395 [Contig_View]  HS6ST2 [Vega]
ICGC DataPortalENSG00000171004
TCGA cBioPortalHS6ST2
AceView (NCBI)HS6ST2
Genatlas (Paris)HS6ST2
WikiGenes90161
SOURCE (Princeton)HS6ST2
Genetics Home Reference (NIH)HS6ST2
Genomic and cartography
GoldenPath hg38 (UCSC)HS6ST2  -     chrX:132626010-132961395 -  Xq26.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HS6ST2  -     Xq26.2   [Description]    (hg19-Feb_2009)
EnsemblHS6ST2 - Xq26.2 [CytoView hg19]  HS6ST2 - Xq26.2 [CytoView hg38]
Mapping of homologs : NCBIHS6ST2 [Mapview hg19]  HS6ST2 [Mapview hg38]
OMIM300545   
Gene and transcription
Genbank (Entrez)AB067776 AB067777 AI253113 AK027720 AK056706
RefSeq transcript (Entrez)NM_001077188 NM_147175
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HS6ST2
Cluster EST : UnigeneHs.385956 [ NCBI ]
CGAP (NCI)Hs.385956
Alternative Splicing GalleryENSG00000171004
Gene ExpressionHS6ST2 [ NCBI-GEO ]   HS6ST2 [ EBI - ARRAY_EXPRESS ]   HS6ST2 [ SEEK ]   HS6ST2 [ MEM ]
Gene Expression Viewer (FireBrowse)HS6ST2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90161
GTEX Portal (Tissue expression)HS6ST2
Human Protein AtlasENSG00000171004-HS6ST2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96MM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96MM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96MM7
Splice isoforms : SwissVarQ96MM7
PhosPhoSitePlusQ96MM7
Domains : Interpro (EBI)Heparan_SO4-6-sulfoTrfase    P-loop_NTPase    Sulfotransferase   
Domain families : Pfam (Sanger)Sulfotransfer_2 (PF03567)   
Domain families : Pfam (NCBI)pfam03567   
Conserved Domain (NCBI)HS6ST2
DMDM Disease mutations90161
Blocks (Seattle)HS6ST2
SuperfamilyQ96MM7
Human Protein Atlas [tissue]ENSG00000171004-HS6ST2 [tissue]
Peptide AtlasQ96MM7
HPRD06590
IPIIPI00157454   IPI00160316   IPI01012150   IPI00922542   IPI00395692   IPI00937318   
Protein Interaction databases
DIP (DOE-UCLA)Q96MM7
IntAct (EBI)Q96MM7
FunCoupENSG00000171004
BioGRIDHS6ST2
STRING (EMBL)HS6ST2
ZODIACHS6ST2
Ontologies - Pathways
QuickGOQ96MM7
Ontology : AmiGOGolgi membrane  nucleoplasm  glycosaminoglycan biosynthetic process  heparan sulfate proteoglycan biosynthetic process, enzymatic modification  integral component of membrane  heparan sulfate 6-O-sulfotransferase activity  heparan sulfate 6-O-sulfotransferase activity  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  nucleoplasm  glycosaminoglycan biosynthetic process  heparan sulfate proteoglycan biosynthetic process, enzymatic modification  integral component of membrane  heparan sulfate 6-O-sulfotransferase activity  heparan sulfate 6-O-sulfotransferase activity  extracellular exosome  
Pathways : KEGGGlycosaminoglycan biosynthesis - heparan sulfate / heparin   
NDEx NetworkHS6ST2
Atlas of Cancer Signalling NetworkHS6ST2
Wikipedia pathwaysHS6ST2
Orthology - Evolution
OrthoDB90161
GeneTree (enSembl)ENSG00000171004
Phylogenetic Trees/Animal Genes : TreeFamHS6ST2
HOVERGENQ96MM7
HOGENOMQ96MM7
Homologs : HomoloGeneHS6ST2
Homology/Alignments : Family Browser (UCSC)HS6ST2
Gene fusions - Rearrangements
Fusion : MitelmanHS6ST2/NPFFR2 [Xq26.2/4q13.3]  
Fusion : MitelmanKIAA1755/HS6ST2 [20q11.23/Xq26.2]  [t(X;20)(q26;q11)]  
Fusion : MitelmanTTC28/HS6ST2 [22q12.1/Xq26.2]  [t(X;22)(q26;q12)]  
Fusion: TCGA_MDACCHS6ST2 Xq26.2 NPFFR2 4q13.3 BLCA
Fusion: TCGA_MDACCKIAA1755 20q11.23 HS6ST2 Xq26.2 BRCA
Tumor Fusion PortalHS6ST2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHS6ST2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HS6ST2
dbVarHS6ST2
ClinVarHS6ST2
1000_GenomesHS6ST2 
Exome Variant ServerHS6ST2
ExAC (Exome Aggregation Consortium)ENSG00000171004
GNOMAD BrowserENSG00000171004
Genetic variants : HAPMAP90161
Genomic Variants (DGV)HS6ST2 [DGVbeta]
DECIPHERHS6ST2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHS6ST2 
Mutations
ICGC Data PortalHS6ST2 
TCGA Data PortalHS6ST2 
Broad Tumor PortalHS6ST2
OASIS PortalHS6ST2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHS6ST2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHS6ST2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch HS6ST2
DgiDB (Drug Gene Interaction Database)HS6ST2
DoCM (Curated mutations)HS6ST2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HS6ST2 (select a term)
intoGenHS6ST2
Cancer3DHS6ST2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300545   
Orphanet
DisGeNETHS6ST2
MedgenHS6ST2
Genetic Testing Registry HS6ST2
NextProtQ96MM7 [Medical]
TSGene90161
GENETestsHS6ST2
Target ValidationHS6ST2
Huge Navigator HS6ST2 [HugePedia]
snp3D : Map Gene to Disease90161
BioCentury BCIQHS6ST2
ClinGenHS6ST2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90161
Chemical/Pharm GKB GenePA134950831
Clinical trialHS6ST2
Miscellaneous
canSAR (ICR)HS6ST2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHS6ST2
EVEXHS6ST2
GoPubMedHS6ST2
iHOPHS6ST2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:16:53 CET 2017

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