Identity
HGNC
LOCATION
5q23.1
LOCUSID
ALIAS
DBP,MFE-2,MFP-2,MPF-2,PRLTS1,SDR8C1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3295
MIM: 601860
HGNC: 5213
Ensembl: ENSG00000133835
Variants:
dbSNP: 3295
ClinVar: 3295
TCGA: ENSG00000133835
COSMIC: HSD17B4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 39052101 | 2024 | Exome sequencing reveals pathogenic mutations in the LARS2 and HSD17B4 genes associated with Perrault syndrome and D-bifunctional protein deficiency in Moroccan families. | 0 |
| 39052101 | 2024 | Exome sequencing reveals pathogenic mutations in the LARS2 and HSD17B4 genes associated with Perrault syndrome and D-bifunctional protein deficiency in Moroccan families. | 0 |
| 37378696 | 2023 | HSD17B4 methylation enhances glucose dependence of BT-474 breast cancer cells and increases lapatinib sensitivity. | 0 |
| 37378696 | 2023 | HSD17B4 methylation enhances glucose dependence of BT-474 breast cancer cells and increases lapatinib sensitivity. | 0 |
| 33935042 | 2021 | The Peroxisomal Localization of Hsd17b4 Is Regulated by Its Interaction with Phosphatidylserine. | 3 |
| 33935042 | 2021 | The Peroxisomal Localization of Hsd17b4 Is Regulated by Its Interaction with Phosphatidylserine. | 3 |
| 32678070 | 2020 | Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer. | 11 |
| 33115767 | 2020 | Rapid whole-genome sequencing identifies a homozygous novel variant, His540Arg, in HSD17B4 resulting in D-bifunctional protein deficiency disorder diagnosis. | 3 |
| 32678070 | 2020 | Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer. | 11 |
| 33115767 | 2020 | Rapid whole-genome sequencing identifies a homozygous novel variant, His540Arg, in HSD17B4 resulting in D-bifunctional protein deficiency disorder diagnosis. | 3 |
| 30540494 | 2019 | Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4. | 58 |
| 30747222 | 2019 | 17β‑hydroxysteroid dehydrogenase 4 induces liver cancer proliferation‑associated genes via STAT3 activation. | 5 |
| 30540494 | 2019 | Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4. | 58 |
| 30747222 | 2019 | 17β‑hydroxysteroid dehydrogenase 4 induces liver cancer proliferation‑associated genes via STAT3 activation. | 5 |
| 26970254 | 2017 | Expanding the genotypic spectrum of Perrault syndrome. | 45 |
Citation
Dessen P
HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50895/hsd17b4
