| Nomenclature |
|---|
| HGNC (Hugo) | HSF2 5225 |
| Cards |
|---|
| Entrez_Gene (NCBI) | HSF2 heat shock transcription factor 2 |
| Aliases | HSF; HSTF |
| GeneCards (Weizmann) | HSF2 |
| Ensembl hg19 (Hinxton) | ENSG00000025156 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000025156 [Gene_View] ENSG00000025156 [Sequence] chr6:122399652-122433119 [Contig_View] HSF2 [Vega] |
| ICGC DataPortal | ENSG00000025156 |
| TCGA cBioPortal | HSF2 |
| AceView (NCBI) | HSF2 |
| Genatlas (Paris) | HSF2 |
| SOURCE (Princeton) | HSF2 |
| Genetics Home Reference (NIH) | HSF2 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | HSF2 - chr6:122399652-122433119 + 6q22.31 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | HSF2 - 6q22.31 [Description] (hg19-Feb_2009) |
| GoldenPath | HSF2 - 6q22.31 [CytoView hg19] HSF2 - 6q22.31 [CytoView hg38] |
| ImmunoBase | ENSG00000025156 |
| genome Data Viewer NCBI | HSF2 [Mapview hg19] |
| OMIM | 140581 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK225593 AK225594 AK294624 AK316377 BC005329 |
| RefSeq transcript (Entrez) | NM_001135564 NM_001243094 NM_004506 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | HSF2 |
| Alternative Splicing Gallery | ENSG00000025156 |
| Gene Expression | HSF2 [ NCBI-GEO ] HSF2 [ EBI - ARRAY_EXPRESS ]
HSF2 [ SEEK ] HSF2 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | HSF2 [ Firebrowse - Broad ] |
| Genevisible | Expression of HSF2 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 3298 |
| GTEX Portal (Tissue expression) | HSF2 |
| Human Protein Atlas | ENSG00000025156-HSF2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q03933 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q03933 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q03933 |
| Splice isoforms : SwissVar | Q03933 |
| PhosPhoSitePlus | Q03933 |
| Domaine pattern : Prosite (Expaxy) | HSF_DOMAIN (PS00434) |
| Domains : Interpro (EBI) | HSF2 HSF_DNA-bd HSF_fam Vert_HSTF_C WH-like_DNA-bd_sf WH_DNA-bd_sf |
| Domain families : Pfam (Sanger) | HSF_DNA-bind (PF00447) Vert_HS_TF (PF06546) |
| Domain families : Pfam (NCBI) | pfam00447 pfam06546 |
| Domain families : Smart (EMBL) | HSF (SM00415) |
| Conserved Domain (NCBI) | HSF2 |
| Blocks (Seattle) | HSF2 |
| PDB (RSDB) | 5D8K 5D8L 5HDK |
| PDB Europe | 5D8K 5D8L 5HDK |
| PDB (PDBSum) | 5D8K 5D8L 5HDK |
| PDB (IMB) | 5D8K 5D8L 5HDK |
| Structural Biology KnowledgeBase | 5D8K 5D8L 5HDK |
| SCOP (Structural Classification of Proteins) | 5D8K 5D8L 5HDK |
| CATH (Classification of proteins structures) | 5D8K 5D8L 5HDK |
| Superfamily | Q03933 |
| Human Protein Atlas [tissue] | ENSG00000025156-HSF2 [tissue] |
| Peptide Atlas | Q03933 |
| HPRD | 00779 |
| IPI | IPI00012878 IPI00913872 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q03933 |
| IntAct (EBI) | Q03933 |
| BioGRID | HSF2 |
| STRING (EMBL) | HSF2 |
| ZODIAC | HSF2 |
| Ontologies - Pathways |
|---|
| QuickGO | Q03933 |
| Ontology : AmiGO | nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity transcription coactivator activity protein binding nucleus nucleoplasm cytoplasm transcription by RNA polymerase II spermatogenesis cellular response to heat host cell nucleus identical protein binding sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to stress positive regulation of transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter in response to heat stress |
| Ontology : EGO-EBI | nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity transcription coactivator activity protein binding nucleus nucleoplasm cytoplasm transcription by RNA polymerase II spermatogenesis cellular response to heat host cell nucleus identical protein binding sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to stress positive regulation of transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter in response to heat stress |
| NDEx Network | HSF2 |
| Atlas of Cancer Signalling Network | HSF2 |
| Wikipedia pathways | HSF2 |
| Orthology - Evolution |
|---|
| OrthoDB | 3298 |
| GeneTree (enSembl) | ENSG00000025156 |
| Phylogenetic Trees/Animal Genes : TreeFam | HSF2 |
| HOGENOM | Q03933 |
| Homologs : HomoloGene | HSF2 |
| Homology/Alignments : Family Browser (UCSC) | HSF2 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | HSF2 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | HSF2 [hg38] |
| dbVar | HSF2 |
| ClinVar | HSF2 |
| Monarch | HSF2 |
| 1000_Genomes | HSF2 |
| Exome Variant Server | HSF2 |
| GNOMAD Browser | ENSG00000025156 |
| Varsome Browser | HSF2 |
| Genomic Variants (DGV) | HSF2 [DGVbeta] |
| DECIPHER | HSF2 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | HSF2 |
| Mutations |
|---|
| ICGC Data Portal | HSF2 |
| TCGA Data Portal | HSF2 |
| Broad Tumor Portal | HSF2 |
| OASIS Portal | HSF2 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | HSF2 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | HSF2 |
| Mutations and Diseases : HGMD | HSF2 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search HSF2 |
| DgiDB (Drug Gene Interaction Database) | HSF2 |
| DoCM (Curated mutations) | HSF2 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | HSF2 (select a term) |
| intoGen | HSF2 |
| Cancer3D | HSF2(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 140581 |
| Orphanet | |
| DisGeNET | HSF2 |
| Medgen | HSF2 |
| Genetic Testing Registry | HSF2
|
| NextProt | Q03933 [Medical] |
| GENETests | HSF2 |
| Target Validation | HSF2 |
| Huge Navigator |
HSF2 [HugePedia] |
| ClinGen | HSF2 |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | HSF2 |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA29494 |
| Pharos | Q03933 |
| Clinical trial | HSF2 |
| Miscellaneous |
|---|
| canSAR (ICR) | HSF2 (select the gene name) |
| Harmonizome | HSF2 |
| DataMed Index | HSF2 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 62 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | HSF2 |
