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HSF2 (heat shock transcription factor 2)

Identity

Alias (NCBI)HSF 2
HSTF 2
HGNC (Hugo) HSF2
LocusID (NCBI) 3298
Atlas_Id 43866
Location 6q22.31  [Link to chromosome band 6q22]
Location_base_pair Starts at 122399652 and ends at 122433119 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HSF2 (6q22.31) / SERINC1 (6q22.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HSF2   5225
Cards
Entrez_Gene (NCBI)HSF2    heat shock transcription factor 2
AliasesHSF; HSTF
GeneCards (Weizmann)HSF2
Ensembl hg19 (Hinxton)ENSG00000025156 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000025156 [Gene_View]  ENSG00000025156 [Sequence]  chr6:122399652-122433119 [Contig_View]  HSF2 [Vega]
ICGC DataPortalENSG00000025156
TCGA cBioPortalHSF2
AceView (NCBI)HSF2
Genatlas (Paris)HSF2
SOURCE (Princeton)HSF2
Genetics Home Reference (NIH)HSF2
Genomic and cartography
GoldenPath hg38 (UCSC)HSF2  -     chr6:122399652-122433119 +  6q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HSF2  -     6q22.31   [Description]    (hg19-Feb_2009)
GoldenPathHSF2 - 6q22.31 [CytoView hg19]  HSF2 - 6q22.31 [CytoView hg38]
ImmunoBaseENSG00000025156
Genome Data Viewer NCBIHSF2 [Mapview hg19]  
OMIM140581   
Gene and transcription
Genbank (Entrez)AK225593 AK225594 AK294624 AK316377 BC005329
RefSeq transcript (Entrez)NM_001135564 NM_001243094 NM_004506
Consensus coding sequences : CCDS (NCBI)HSF2
Gene ExpressionHSF2 [ NCBI-GEO ]   HSF2 [ EBI - ARRAY_EXPRESS ]   HSF2 [ SEEK ]   HSF2 [ MEM ]
Gene Expression Viewer (FireBrowse)HSF2 [ Firebrowse - Broad ]
GenevisibleExpression of HSF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3298
GTEX Portal (Tissue expression)HSF2
Human Protein AtlasENSG00000025156-HSF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ03933   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ03933  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ03933
PhosPhoSitePlusQ03933
Domaine pattern : Prosite (Expaxy)HSF_DOMAIN (PS00434)   
Domains : Interpro (EBI)HSF2    HSF_DNA-bd    HSF_fam    Vert_HSTF_C    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)HSF_DNA-bind (PF00447)    Vert_HS_TF (PF06546)   
Domain families : Pfam (NCBI)pfam00447    pfam06546   
Domain families : Smart (EMBL)HSF (SM00415)  
Conserved Domain (NCBI)HSF2
PDB (RSDB)5D8K    5D8L    5HDK   
PDB Europe5D8K    5D8L    5HDK   
PDB (PDBSum)5D8K    5D8L    5HDK   
PDB (IMB)5D8K    5D8L    5HDK   
Structural Biology KnowledgeBase5D8K    5D8L    5HDK   
SCOP (Structural Classification of Proteins)5D8K    5D8L    5HDK   
CATH (Classification of proteins structures)5D8K    5D8L    5HDK   
SuperfamilyQ03933
AlphaFold pdb e-kbQ03933   
Human Protein Atlas [tissue]ENSG00000025156-HSF2 [tissue]
HPRD00779
Protein Interaction databases
DIP (DOE-UCLA)Q03933
IntAct (EBI)Q03933
BioGRIDHSF2
STRING (EMBL)HSF2
ZODIACHSF2
Ontologies - Pathways
QuickGOQ03933
Ontology : AmiGOchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription by RNA polymerase II  spermatogenesis  identical protein binding  positive regulation of transcription by RNA polymerase II  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBIchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription by RNA polymerase II  spermatogenesis  identical protein binding  positive regulation of transcription by RNA polymerase II  sequence-specific double-stranded DNA binding  
NDEx NetworkHSF2
Atlas of Cancer Signalling NetworkHSF2
Wikipedia pathwaysHSF2
Orthology - Evolution
OrthoDB3298
GeneTree (enSembl)ENSG00000025156
Phylogenetic Trees/Animal Genes : TreeFamHSF2
Homologs : HomoloGeneHSF2
Homology/Alignments : Family Browser (UCSC)HSF2
Gene fusions - Rearrangements
Fusion : QuiverHSF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHSF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HSF2
dbVarHSF2
ClinVarHSF2
MonarchHSF2
1000_GenomesHSF2 
Exome Variant ServerHSF2
GNOMAD BrowserENSG00000025156
Varsome BrowserHSF2
ACMGHSF2 variants
VarityQ03933
Genomic Variants (DGV)HSF2 [DGVbeta]
DECIPHERHSF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHSF2 
Mutations
ICGC Data PortalHSF2 
TCGA Data PortalHSF2 
Broad Tumor PortalHSF2
OASIS PortalHSF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHSF2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHSF2
Mutations and Diseases : HGMDHSF2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHSF2
DgiDB (Drug Gene Interaction Database)HSF2
DoCM (Curated mutations)HSF2
CIViC (Clinical Interpretations of Variants in Cancer)HSF2
Cancer3DHSF2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM140581   
Orphanet
DisGeNETHSF2
MedgenHSF2
Genetic Testing Registry HSF2
NextProtQ03933 [Medical]
GENETestsHSF2
Target ValidationHSF2
Huge Navigator HSF2 [HugePedia]
ClinGenHSF2
Clinical trials, drugs, therapy
MyCancerGenomeHSF2
Protein Interactions : CTDHSF2
Pharm GKB GenePA29494
PharosQ03933
Clinical trialHSF2
Miscellaneous
canSAR (ICR)HSF2
HarmonizomeHSF2
DataMed IndexHSF2
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHSF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:13:06 CEST 2021

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