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HSF4 (heat shock transcription factor 4)

Identity

Alias_namesCTM
cataract
Other aliasCTRCT5
HGNC (Hugo) HSF4
LocusID (NCBI) 3299
Atlas_Id 53157
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 67163385 and ends at 67169945 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HSF4   5227
Cards
Entrez_Gene (NCBI)HSF4  3299  heat shock transcription factor 4
AliasesCTM; CTRCT5
GeneCards (Weizmann)HSF4
Ensembl hg19 (Hinxton)ENSG00000102878 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102878 [Gene_View]  chr16:67163385-67169945 [Contig_View]  HSF4 [Vega]
ICGC DataPortalENSG00000102878
TCGA cBioPortalHSF4
AceView (NCBI)HSF4
Genatlas (Paris)HSF4
WikiGenes3299
SOURCE (Princeton)HSF4
Genetics Home Reference (NIH)HSF4
Genomic and cartography
GoldenPath hg38 (UCSC)HSF4  -     chr16:67163385-67169945 +  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HSF4  -     16q22.1   [Description]    (hg19-Feb_2009)
EnsemblHSF4 - 16q22.1 [CytoView hg19]  HSF4 - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBIHSF4 [Mapview hg19]  HSF4 [Mapview hg38]
OMIM116800   602438   
Gene and transcription
Genbank (Entrez)AB029348 AK225152 AK293631 AK296210 AK307211
RefSeq transcript (Entrez)NM_001040667 NM_001538
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HSF4
Cluster EST : UnigeneHs.710714 [ NCBI ]
CGAP (NCI)Hs.710714
Alternative Splicing GalleryENSG00000102878
Gene ExpressionHSF4 [ NCBI-GEO ]   HSF4 [ EBI - ARRAY_EXPRESS ]   HSF4 [ SEEK ]   HSF4 [ MEM ]
Gene Expression Viewer (FireBrowse)HSF4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3299
GTEX Portal (Tissue expression)HSF4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULV5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULV5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULV5
Splice isoforms : SwissVarQ9ULV5
PhosPhoSitePlusQ9ULV5
Domaine pattern : Prosite (Expaxy)HSF_DOMAIN (PS00434)   
Domains : Interpro (EBI)HSF4    HSF_DNA-bd    HSF_fam    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)HSF_DNA-bind (PF00447)   
Domain families : Pfam (NCBI)pfam00447   
Domain families : Smart (EMBL)HSF (SM00415)  
Conserved Domain (NCBI)HSF4
DMDM Disease mutations3299
Blocks (Seattle)HSF4
SuperfamilyQ9ULV5
Human Protein AtlasENSG00000102878
Peptide AtlasQ9ULV5
HPRD03896
IPIIPI00008456   IPI00220197   IPI00974388   IPI00909210   IPI00974489   IPI00973830   IPI00974247   IPI00982339   IPI00975578   IPI00985404   IPI00980886   IPI00976979   IPI00977402   IPI00981631   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULV5
IntAct (EBI)Q9ULV5
FunCoupENSG00000102878
BioGRIDHSF4
STRING (EMBL)HSF4
ZODIACHSF4
Ontologies - Pathways
QuickGOQ9ULV5
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  transcription, DNA-templated  regulation of transcription, DNA-templated  visual perception  positive regulation of cell proliferation  nuclear speck  histone H3-K9 demethylation  camera-type eye development  sequence-specific DNA binding  positive regulation of cell differentiation  positive regulation of transcription from RNA polymerase II promoter  cell development  protein homotrimerization  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  transcription, DNA-templated  regulation of transcription, DNA-templated  visual perception  positive regulation of cell proliferation  nuclear speck  histone H3-K9 demethylation  camera-type eye development  sequence-specific DNA binding  positive regulation of cell differentiation  positive regulation of transcription from RNA polymerase II promoter  cell development  protein homotrimerization  
NDEx NetworkHSF4
Atlas of Cancer Signalling NetworkHSF4
Wikipedia pathwaysHSF4
Orthology - Evolution
OrthoDB3299
GeneTree (enSembl)ENSG00000102878
Phylogenetic Trees/Animal Genes : TreeFamHSF4
HOVERGENQ9ULV5
HOGENOMQ9ULV5
Homologs : HomoloGeneHSF4
Homology/Alignments : Family Browser (UCSC)HSF4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHSF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HSF4
dbVarHSF4
ClinVarHSF4
1000_GenomesHSF4 
Exome Variant ServerHSF4
ExAC (Exome Aggregation Consortium)HSF4 (select the gene name)
Genetic variants : HAPMAP3299
Genomic Variants (DGV)HSF4 [DGVbeta]
DECIPHERHSF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHSF4 
Mutations
ICGC Data PortalHSF4 
TCGA Data PortalHSF4 
Broad Tumor PortalHSF4
OASIS PortalHSF4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHSF4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHSF4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch HSF4
DgiDB (Drug Gene Interaction Database)HSF4
DoCM (Curated mutations)HSF4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HSF4 (select a term)
intoGenHSF4
Cancer3DHSF4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM116800    602438   
Orphanet23423    14011   
MedgenHSF4
Genetic Testing Registry HSF4
NextProtQ9ULV5 [Medical]
TSGene3299
GENETestsHSF4
Target ValidationHSF4
Huge Navigator HSF4 [HugePedia]
snp3D : Map Gene to Disease3299
BioCentury BCIQHSF4
ClinGenHSF4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3299
Chemical/Pharm GKB GenePA29496
Clinical trialHSF4
Miscellaneous
canSAR (ICR)HSF4 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHSF4
EVEXHSF4
GoPubMedHSF4
iHOPHSF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:03:29 CEST 2017

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