Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 259217
MIM: 610701
HGNC: 19022
Ensembl: ENSG00000165868
Variants:
dbSNP: 259217
ClinVar: 259217
TCGA: ENSG00000165868
COSMIC: HSPA12A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165868 | ENST00000369209 | O43301 |
| ENSG00000165868 | ENST00000480802 | K7ELE6 |
| ENSG00000165868 | ENST00000635765 | A0A1B0GTF3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Cellular response to heat stress | REACTOME | R-HSA-3371556 |
| Regulation of HSF1-mediated heat shock response | REACTOME | R-HSA-3371453 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37942840 | 2024 | Heat-shock protein A12A attenuates oxygen-glucose deprivation/reoxygenation-induced human brain microvascular endothelial cell dysfunction via PGC-1α/SIRT3 pathway. | 0 |
| 37942840 | 2024 | Heat-shock protein A12A attenuates oxygen-glucose deprivation/reoxygenation-induced human brain microvascular endothelial cell dysfunction via PGC-1α/SIRT3 pathway. | 0 |
| 37245169 | 2023 | HSPA12A was identified as a key driver in colorectal cancer GWAS loci 10q26.12 and modulated by an enhancer-promoter interaction. | 0 |
| 37245169 | 2023 | HSPA12A was identified as a key driver in colorectal cancer GWAS loci 10q26.12 and modulated by an enhancer-promoter interaction. | 0 |
| 35050463 | 2022 | Heat shock protein A12A activates migration of hepatocellular carcinoma cells in a monocarboxylate transporter 4-dependent manner. | 4 |
| 36394206 | 2022 | Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer. | 5 |
| 35050463 | 2022 | Heat shock protein A12A activates migration of hepatocellular carcinoma cells in a monocarboxylate transporter 4-dependent manner. | 4 |
| 36394206 | 2022 | Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer. | 5 |
| 32128976 | 2020 | Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth. | 7 |
| 32754264 | 2020 | HSPA12A unstabilizes CD147 to inhibit lactate export and migration in human renal cell carcinoma. | 12 |
| 32128976 | 2020 | Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth. | 7 |
| 32754264 | 2020 | HSPA12A unstabilizes CD147 to inhibit lactate export and migration in human renal cell carcinoma. | 12 |
| 25798051 | 2015 | Upregulation of heat shock proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in tumour tissues is associated with poor outcomes from HBV-related early-stage hepatocellular carcinoma. | 83 |
| 26302849 | 2015 | Polymorphisms of PRLHR and HSPA12A and risk of gastric and colorectal cancer in the Chinese Han population. | 11 |
| 25798051 | 2015 | Upregulation of heat shock proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in tumour tissues is associated with poor outcomes from HBV-related early-stage hepatocellular carcinoma. | 83 |
Citation
Dessen P
HSPA12A (heat shock protein family A (Hsp70) member 12A)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47353/hspa12a
