Identity
HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
HSP70-1L,HSP70-HOM,HSP70T,hum70t
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3305
MIM: 140559
HGNC: 5234
Ensembl: ENSG00000204390
Variants:
dbSNP: 3305
ClinVar: 3305
TCGA: ENSG00000204390
COSMIC: HSPA1L
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204390 | ENST00000375654 | P34931 |
| ENSG00000204390 | ENST00000375654 | A0A1U9X7W7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444065 | Epilepsy | Disease | ClinicalAnnotation | associated | PD | 16538175 | |
| PA448785 | carbamazepine | Chemical | ClinicalAnnotation | associated | PD | 16538175 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36345598 | 2023 | Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients. | 1 |
| 36345598 | 2023 | Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients. | 1 |
| 34796524 | 2022 | Expressions of HSPA1L and HSPA9 are associated with poor sperm quality of low-motility spermatozoa in fertile men. | 3 |
| 34796524 | 2022 | Expressions of HSPA1L and HSPA9 are associated with poor sperm quality of low-motility spermatozoa in fertile men. | 3 |
| 33742129 | 2021 | A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease. | 4 |
| 34429451 | 2021 | Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth. | 8 |
| 33742129 | 2021 | A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease. | 4 |
| 34429451 | 2021 | Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth. | 8 |
| 31816668 | 2020 | Association of polymorphism in heat shock protein 70 genes with type 2 diabetes in Bangladeshi population. | 4 |
| 32039449 | 2020 | HSPA1L rs1061581 polymorphism is associated with the risk of preeclampsia in Han Chinese women. | 0 |
| 32971893 | 2020 | HSPA1L Enhances Cancer Stem Cell-Like Properties by Activating IGF1Rβ and Regulating β-Catenin Transcription. | 7 |
| 31816668 | 2020 | Association of polymorphism in heat shock protein 70 genes with type 2 diabetes in Bangladeshi population. | 4 |
| 32039449 | 2020 | HSPA1L rs1061581 polymorphism is associated with the risk of preeclampsia in Han Chinese women. | 0 |
| 32971893 | 2020 | HSPA1L Enhances Cancer Stem Cell-Like Properties by Activating IGF1Rβ and Regulating β-Catenin Transcription. | 7 |
| 31228677 | 2019 | HSPA1L and HSPA1B gene polymorphisms and haplotypes are associated with idiopathic male infertility in Iranian population. | 6 |
Citation
Dessen P
HSPA1L (heat shock protein family A (Hsp70) member 1 like)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40873/hspa1l
