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HSPA6 (heat shock protein family A (Hsp70) member 6)

Identity

Alias_namesheat shock 70kD protein 6 (HSP70B')
heat shock 70kDa protein 6 (HSP70B')
Alias_symbol (synonym)HSP70B'
Other alias
HGNC (Hugo) HSPA6
LocusID (NCBI) 3310
Atlas_Id 40877
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 161524540 and ends at 161526897 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HSPA6   5239
Cards
Entrez_Gene (NCBI)HSPA6  3310  heat shock protein family A (Hsp70) member 6
AliasesHSP70B'
GeneCards (Weizmann)HSPA6
Ensembl hg19 (Hinxton)ENSG00000173110 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173110 [Gene_View]  chr1:161524540-161526897 [Contig_View]  HSPA6 [Vega]
ICGC DataPortalENSG00000173110
TCGA cBioPortalHSPA6
AceView (NCBI)HSPA6
Genatlas (Paris)HSPA6
WikiGenes3310
SOURCE (Princeton)HSPA6
Genetics Home Reference (NIH)HSPA6
Genomic and cartography
GoldenPath hg38 (UCSC)HSPA6  -     chr1:161524540-161526897 +  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HSPA6  -     1q23.3   [Description]    (hg19-Feb_2009)
EnsemblHSPA6 - 1q23.3 [CytoView hg19]  HSPA6 - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIHSPA6 [Mapview hg19]  HSPA6 [Mapview hg38]
OMIM140555   
Gene and transcription
Genbank (Entrez)AK093925 AK223362 AK295212 AK312756 BC004279
RefSeq transcript (Entrez)NM_002155
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HSPA6
Cluster EST : UnigeneHs.654614 [ NCBI ]
CGAP (NCI)Hs.654614
Alternative Splicing GalleryENSG00000173110
Gene ExpressionHSPA6 [ NCBI-GEO ]   HSPA6 [ EBI - ARRAY_EXPRESS ]   HSPA6 [ SEEK ]   HSPA6 [ MEM ]
Gene Expression Viewer (FireBrowse)HSPA6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3310
GTEX Portal (Tissue expression)HSPA6
Human Protein AtlasENSG00000173110-HSPA6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17066   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17066  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17066
Splice isoforms : SwissVarP17066
PhosPhoSitePlusP17066
Domaine pattern : Prosite (Expaxy)HSP70_1 (PS00297)    HSP70_2 (PS00329)    HSP70_3 (PS01036)   
Domains : Interpro (EBI)Heat_shock_70_CS    HSP70_C    HSP70_peptide-bd    Hsp_70_fam   
Domain families : Pfam (Sanger)HSP70 (PF00012)   
Domain families : Pfam (NCBI)pfam00012   
Conserved Domain (NCBI)HSPA6
DMDM Disease mutations3310
Blocks (Seattle)HSPA6
PDB (SRS)3FE1   
PDB (PDBSum)3FE1   
PDB (IMB)3FE1   
PDB (RSDB)3FE1   
Structural Biology KnowledgeBase3FE1   
SCOP (Structural Classification of Proteins)3FE1   
CATH (Classification of proteins structures)3FE1   
SuperfamilyP17066
Human Protein Atlas [tissue]ENSG00000173110-HSPA6 [tissue]
Peptide AtlasP17066
HPRD00775
IPIIPI00339269   IPI01009562   
Protein Interaction databases
DIP (DOE-UCLA)P17066
IntAct (EBI)P17066
FunCoupENSG00000173110
BioGRIDHSPA6
STRING (EMBL)HSPA6
ZODIACHSPA6
Ontologies - Pathways
QuickGOP17066
Ontology : AmiGOprotein binding  ATP binding  extracellular region  cytoplasm  centriole  cytosol  response to unfolded protein  COP9 signalosome  enzyme binding  heat shock protein binding  cellular response to heat  cellular response to heat  secretory granule lumen  protein refolding  ATPase activity, coupled  neutrophil degranulation  unfolded protein binding  extracellular exosome  cellular heat acclimation  blood microparticle  ficolin-1-rich granule lumen  
Ontology : EGO-EBIprotein binding  ATP binding  extracellular region  cytoplasm  centriole  cytosol  response to unfolded protein  COP9 signalosome  enzyme binding  heat shock protein binding  cellular response to heat  cellular response to heat  secretory granule lumen  protein refolding  ATPase activity, coupled  neutrophil degranulation  unfolded protein binding  extracellular exosome  cellular heat acclimation  blood microparticle  ficolin-1-rich granule lumen  
Pathways : KEGG   
NDEx NetworkHSPA6
Atlas of Cancer Signalling NetworkHSPA6
Wikipedia pathwaysHSPA6
Orthology - Evolution
OrthoDB3310
GeneTree (enSembl)ENSG00000173110
Phylogenetic Trees/Animal Genes : TreeFamHSPA6
HOVERGENP17066
HOGENOMP17066
Homologs : HomoloGeneHSPA6
Homology/Alignments : Family Browser (UCSC)HSPA6
Gene fusions - Rearrangements
Tumor Fusion PortalHSPA6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHSPA6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HSPA6
dbVarHSPA6
ClinVarHSPA6
1000_GenomesHSPA6 
Exome Variant ServerHSPA6
ExAC (Exome Aggregation Consortium)ENSG00000173110
GNOMAD BrowserENSG00000173110
Genetic variants : HAPMAP3310
Genomic Variants (DGV)HSPA6 [DGVbeta]
DECIPHERHSPA6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHSPA6 
Mutations
ICGC Data PortalHSPA6 
TCGA Data PortalHSPA6 
Broad Tumor PortalHSPA6
OASIS PortalHSPA6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHSPA6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHSPA6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HSPA6
DgiDB (Drug Gene Interaction Database)HSPA6
DoCM (Curated mutations)HSPA6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HSPA6 (select a term)
intoGenHSPA6
Cancer3DHSPA6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM140555   
Orphanet
DisGeNETHSPA6
MedgenHSPA6
Genetic Testing Registry HSPA6
NextProtP17066 [Medical]
TSGene3310
GENETestsHSPA6
Target ValidationHSPA6
Huge Navigator HSPA6 [HugePedia]
snp3D : Map Gene to Disease3310
BioCentury BCIQHSPA6
ClinGenHSPA6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3310
Chemical/Pharm GKB GenePA29505
Clinical trialHSPA6
Miscellaneous
canSAR (ICR)HSPA6 (select the gene name)
Probes
Litterature
PubMed89 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHSPA6
EVEXHSPA6
GoPubMedHSPA6
iHOPHSPA6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:17:01 CET 2017

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