HSPB11 (heat shock protein family B (small) member 11)

2008-07-01  

Identity

HGNC
HSPB11
LOCATION
1p32.3
LOCUSID
51668
ALIAS
C1orf41,FAP232,HSPCO34,IFT25,PP25
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51668
HGNC: 25019
Ensembl: ENSG00000081870

Variants:

dbSNP: 51668
ClinVar: 51668
TCGA: ENSG00000081870
COSMIC: HSPB11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000081870ENST00000194214Q9Y547
ENSG00000081870ENST00000371376A6NG08
ENSG00000081870ENST00000371377A6NIR2
ENSG00000081870ENST00000371378X6R7Y7

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Intraflagellar transportREACTOMER-HSA-5620924

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
172759512007Preventing apoptotic cell death by a novel small heat shock protein.16
181546562007Correlation between the progressive cytoplasmic expression of a novel small heat shock protein (Hsp16.2) and malignancy in brain tumors.9
265447732016Association between small heat shock protein B11 and the prognostic value of MGMT promoter methylation in patients with high-grade glioma.8
266948162015Small heat shock proteins are induced during multiple sclerosis lesion development in white but not grey matter.5

Citation

Dessen P

HSPB11 (heat shock protein family B (small) member 11)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50194/hspb11