Atlas of Genetics and Cytogenetics in Oncology and Haematology

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HSPB11 (heat shock protein family B (small) member 11)

Identity

Alias_namesC1orf41
chromosome 1 open reading frame 41
heat shock protein family B (small), member 11
Alias_symbol (synonym)HSPCO34
PP25
IFT25
Other alias
HGNC (Hugo) HSPB11
LocusID (NCBI) 51668
Atlas_Id 50194
Location 1p32.3  [Link to chromosome band 1p32]
Location_base_pair Starts at 53921561 and ends at 53945823 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HSPB11 (1p32.3) / ZCCHC11 (1p32.3)HSPB11 1p32.3 / ZCCHC11 1p32.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]

Solid Tumors TT_t0101p32p32ID103635

External links

Nomenclature
HGNC (Hugo)HSPB11   25019
Cards
Entrez_Gene (NCBI)HSPB11  51668  heat shock protein family B (small) member 11
AliasesC1orf41; HSPCO34; IFT25; PP25
GeneCards (Weizmann)HSPB11
Ensembl hg19 (Hinxton)ENSG00000081870 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000081870 [Gene_View]  ENSG00000081870 [Sequence]  chr1:53921561-53945823 [Contig_View]  HSPB11 [Vega]
ICGC DataPortalENSG00000081870
TCGA cBioPortalHSPB11
AceView (NCBI)HSPB11
Genatlas (Paris)HSPB11
WikiGenes51668
SOURCE (Princeton)HSPB11
Genetics Home Reference (NIH)HSPB11
Genomic and cartography
GoldenPath hg38 (UCSC)HSPB11  -     chr1:53921561-53945823 -  1p32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HSPB11  -     1p32.3   [Description]    (hg19-Feb_2009)
GoldenPathHSPB11 - 1p32.3 [CytoView hg19]  HSPB11 - 1p32.3 [CytoView hg38]
ImmunoBaseENSG00000081870
Mapping of homologs : NCBIHSPB11 [Mapview hg19]  HSPB11 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF100747 AF416725 AF417114 AK225916 AW024033
RefSeq transcript (Entrez)NM_001316935 NM_016126
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HSPB11
Cluster EST : UnigeneHs.624686 [ NCBI ]
CGAP (NCI)Hs.624686
Alternative Splicing GalleryENSG00000081870
Gene ExpressionHSPB11 [ NCBI-GEO ]   HSPB11 [ EBI - ARRAY_EXPRESS ]   HSPB11 [ SEEK ]   HSPB11 [ MEM ]
Gene Expression Viewer (FireBrowse)HSPB11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51668
GTEX Portal (Tissue expression)HSPB11
Human Protein AtlasENSG00000081870-HSPB11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y547   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y547  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y547
Splice isoforms : SwissVarQ9Y547
PhosPhoSitePlusQ9Y547
Domains : Interpro (EBI)FA58C    Galactose-bd-like_sf    IFT25   
Domain families : Pfam (Sanger)F5_F8_type_C (PF00754)   
Domain families : Pfam (NCBI)pfam00754   
Conserved Domain (NCBI)HSPB11
DMDM Disease mutations51668
Blocks (Seattle)HSPB11
PDB (RSDB)1TVG    1XPW   
PDB Europe1TVG    1XPW   
PDB (PDBSum)1TVG    1XPW   
PDB (IMB)1TVG    1XPW   
Structural Biology KnowledgeBase1TVG    1XPW   
SCOP (Structural Classification of Proteins)1TVG    1XPW   
CATH (Classification of proteins structures)1TVG    1XPW   
SuperfamilyQ9Y547
Human Protein Atlas [tissue]ENSG00000081870-HSPB11 [tissue]
Peptide AtlasQ9Y547
IPIIPI00098827   IPI00744048   IPI00333618   IPI00640053   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y547
IntAct (EBI)Q9Y547
FunCoupENSG00000081870
BioGRIDHSPB11
STRING (EMBL)HSPB11
ZODIACHSPB11
Ontologies - Pathways
QuickGOQ9Y547
Ontology : AmiGOskeletal system development  kidney development  protein binding  centrosome  cilium  cilium  smoothened signaling pathway  spermatogenesis  heart development  cell differentiation  lung development  intraciliary transport particle B  intraciliary transport particle B  intraciliary transport involved in cilium assembly  metal ion binding  cilium assembly  left/right axis specification  ciliary tip  
Ontology : EGO-EBIskeletal system development  kidney development  protein binding  centrosome  cilium  cilium  smoothened signaling pathway  spermatogenesis  heart development  cell differentiation  lung development  intraciliary transport particle B  intraciliary transport particle B  intraciliary transport involved in cilium assembly  metal ion binding  cilium assembly  left/right axis specification  ciliary tip  
NDEx NetworkHSPB11
Atlas of Cancer Signalling NetworkHSPB11
Wikipedia pathwaysHSPB11
Orthology - Evolution
OrthoDB51668
GeneTree (enSembl)ENSG00000081870
Phylogenetic Trees/Animal Genes : TreeFamHSPB11
HOGENOMQ9Y547
Homologs : HomoloGeneHSPB11
Homology/Alignments : Family Browser (UCSC)HSPB11
Gene fusions - Rearrangements
Fusion : MitelmanHSPB11/ZCCHC11 [1p32.3/1p32.3]  
Fusion PortalHSPB11 1p32.3 ZCCHC11 1p32.3 HNSC
Fusion : QuiverHSPB11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHSPB11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HSPB11
dbVarHSPB11
ClinVarHSPB11
1000_GenomesHSPB11 
Exome Variant ServerHSPB11
ExAC (Exome Aggregation Consortium)ENSG00000081870
GNOMAD BrowserENSG00000081870
Varsome BrowserHSPB11
Genetic variants : HAPMAP51668
Genomic Variants (DGV)HSPB11 [DGVbeta]
DECIPHERHSPB11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHSPB11 
Mutations
ICGC Data PortalHSPB11 
TCGA Data PortalHSPB11 
Broad Tumor PortalHSPB11
OASIS PortalHSPB11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHSPB11  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHSPB11
Mutations and Diseases : HGMDHSPB11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HSPB11
DgiDB (Drug Gene Interaction Database)HSPB11
DoCM (Curated mutations)HSPB11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HSPB11 (select a term)
intoGenHSPB11
Cancer3DHSPB11(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETHSPB11
MedgenHSPB11
Genetic Testing Registry HSPB11
NextProtQ9Y547 [Medical]
TSGene51668
GENETestsHSPB11
Target ValidationHSPB11
Huge Navigator HSPB11 [HugePedia]
snp3D : Map Gene to Disease51668
BioCentury BCIQHSPB11
ClinGenHSPB11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51668
Chemical/Pharm GKB GenePA162391751
Clinical trialHSPB11
Miscellaneous
canSAR (ICR)HSPB11 (select the gene name)
DataMed IndexHSPB11
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHSPB11
EVEXHSPB11
GoPubMedHSPB11
iHOPHSPB11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jan 27 14:46:29 CET 2020
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