Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HSPB6 (heat shock protein family B (small) member 6)

Identity

Alias_namesregulatory subunit 91
Alias_symbol (synonym)FLJ32389
Hsp20
PPP1R91
Other aliasHEL55
HGNC (Hugo) HSPB6
LocusID (NCBI) 126393
Atlas_Id 47431
Location 19q13.12  [Link to chromosome band 19q13]
Location_base_pair Starts at 35754566 and ends at 35757029 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HSPB6   26511
Cards
Entrez_Gene (NCBI)HSPB6  126393  heat shock protein family B (small) member 6
AliasesHEL55; Hsp20; PPP1R91
GeneCards (Weizmann)HSPB6
Ensembl hg19 (Hinxton)ENSG00000004776 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000004776 [Gene_View]  chr19:35754566-35757029 [Contig_View]  HSPB6 [Vega]
ICGC DataPortalENSG00000004776
TCGA cBioPortalHSPB6
AceView (NCBI)HSPB6
Genatlas (Paris)HSPB6
WikiGenes126393
SOURCE (Princeton)HSPB6
Genetics Home Reference (NIH)HSPB6
Genomic and cartography
GoldenPath hg38 (UCSC)HSPB6  -     chr19:35754566-35757029 -  19q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HSPB6  -     19q13.12   [Description]    (hg19-Feb_2009)
EnsemblHSPB6 - 19q13.12 [CytoView hg19]  HSPB6 - 19q13.12 [CytoView hg38]
Mapping of homologs : NCBIHSPB6 [Mapview hg19]  HSPB6 [Mapview hg38]
OMIM610695   
Gene and transcription
Genbank (Entrez)AJ278121 AK026458 AK056951 AK297852 AK300695
RefSeq transcript (Entrez)NM_144617
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HSPB6
Cluster EST : UnigeneHs.744178 [ NCBI ]
CGAP (NCI)Hs.744178
Alternative Splicing GalleryENSG00000004776
Gene ExpressionHSPB6 [ NCBI-GEO ]   HSPB6 [ EBI - ARRAY_EXPRESS ]   HSPB6 [ SEEK ]   HSPB6 [ MEM ]
Gene Expression Viewer (FireBrowse)HSPB6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)126393
GTEX Portal (Tissue expression)HSPB6
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14558   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14558  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14558
Splice isoforms : SwissVarO14558
PhosPhoSitePlusO14558
Domaine pattern : Prosite (Expaxy)HSP20 (PS01031)   
Domains : Interpro (EBI)A-crystallin/Hsp20_dom    Alpha-crystallin/HSP    Alpha-crystallin_B    Alpha-crystallin_N    HSP20    HSP20-like_chaperone   
Domain families : Pfam (Sanger)Crystallin (PF00525)    HSP20 (PF00011)   
Domain families : Pfam (NCBI)pfam00525    pfam00011   
Conserved Domain (NCBI)HSPB6
DMDM Disease mutations126393
Blocks (Seattle)HSPB6
PDB (SRS)4JUS    4JUT    5LTW    5LU1    5LU2    5LUM   
PDB (PDBSum)4JUS    4JUT    5LTW    5LU1    5LU2    5LUM   
PDB (IMB)4JUS    4JUT    5LTW    5LU1    5LU2    5LUM   
PDB (RSDB)4JUS    4JUT    5LTW    5LU1    5LU2    5LUM   
Structural Biology KnowledgeBase4JUS    4JUT    5LTW    5LU1    5LU2    5LUM   
SCOP (Structural Classification of Proteins)4JUS    4JUT    5LTW    5LU1    5LU2    5LUM   
CATH (Classification of proteins structures)4JUS    4JUT    5LTW    5LU1    5LU2    5LUM   
SuperfamilyO14558
Human Protein AtlasENSG00000004776
Peptide AtlasO14558
HPRD08130
IPIIPI00908768   IPI00816376   IPI00022433   
Protein Interaction databases
DIP (DOE-UCLA)O14558
IntAct (EBI)O14558
FunCoupENSG00000004776
BioGRIDHSPB6
STRING (EMBL)HSPB6
ZODIACHSPB6
Ontologies - Pathways
QuickGOO14558
Ontology : AmiGOstructural constituent of eye lens  protein binding  extracellular region  nucleus  cytoplasm  regulation of muscle contraction  negative regulation of cardiac muscle cell apoptotic process  protein homodimerization activity  positive regulation of angiogenesis  unfolded protein binding  chaperone binding  chaperone-mediated protein folding  
Ontology : EGO-EBIstructural constituent of eye lens  protein binding  extracellular region  nucleus  cytoplasm  regulation of muscle contraction  negative regulation of cardiac muscle cell apoptotic process  protein homodimerization activity  positive regulation of angiogenesis  unfolded protein binding  chaperone binding  chaperone-mediated protein folding  
NDEx NetworkHSPB6
Atlas of Cancer Signalling NetworkHSPB6
Wikipedia pathwaysHSPB6
Orthology - Evolution
OrthoDB126393
GeneTree (enSembl)ENSG00000004776
Phylogenetic Trees/Animal Genes : TreeFamHSPB6
HOVERGENO14558
HOGENOMO14558
Homologs : HomoloGeneHSPB6
Homology/Alignments : Family Browser (UCSC)HSPB6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHSPB6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HSPB6
dbVarHSPB6
ClinVarHSPB6
1000_GenomesHSPB6 
Exome Variant ServerHSPB6
ExAC (Exome Aggregation Consortium)HSPB6 (select the gene name)
Genetic variants : HAPMAP126393
Genomic Variants (DGV)HSPB6 [DGVbeta]
DECIPHERHSPB6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHSPB6 
Mutations
ICGC Data PortalHSPB6 
TCGA Data PortalHSPB6 
Broad Tumor PortalHSPB6
OASIS PortalHSPB6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHSPB6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHSPB6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HSPB6
DgiDB (Drug Gene Interaction Database)HSPB6
DoCM (Curated mutations)HSPB6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HSPB6 (select a term)
intoGenHSPB6
Cancer3DHSPB6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610695   
Orphanet
MedgenHSPB6
Genetic Testing Registry HSPB6
NextProtO14558 [Medical]
TSGene126393
GENETestsHSPB6
Target ValidationHSPB6
Huge Navigator HSPB6 [HugePedia]
snp3D : Map Gene to Disease126393
BioCentury BCIQHSPB6
ClinGenHSPB6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD126393
Chemical/Pharm GKB GenePA134983584
Clinical trialHSPB6
Miscellaneous
canSAR (ICR)HSPB6 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHSPB6
EVEXHSPB6
GoPubMedHSPB6
iHOPHSPB6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:37:42 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.