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HTN3 (histatin 3)

Identity

Alias (NCBI)HIS2
HTN2
HTN5
PB
HGNC (Hugo) HTN3
HGNC Alias symbHIS2
LocusID (NCBI) 3347
Atlas_Id 51767
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 70028459 and ends at 70036538 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CGNL1 (15q21.3) / HTN3 (4q13.3)CSNK1G3 (5q23.2) / HTN3 (4q13.3)DAB2IP (9q33.2) / HTN3 (4q13.3)
HTN3 (4q13.3) / OSBPL1A (18q11.2)HTN3 (4q13.3) / RIMS1 (6q13)HTN3 (4q13.3) / RPL6 (12q24.13)
KCNE2 (21q22.11) / HTN3 (4q13.3)DAB2IP 9q33.2 / HTN3 4q13.3KCNE2 21q22.11 / HTN3 4q13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HTN3   5284
Cards
Entrez_Gene (NCBI)HTN3    histatin 3
AliasesHIS2; HTN2; HTN5; PB
GeneCards (Weizmann)HTN3
Ensembl hg19 (Hinxton)ENSG00000205649 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205649 [Gene_View]  ENSG00000205649 [Sequence]  chr4:70028459-70036538 [Contig_View]  HTN3 [Vega]
ICGC DataPortalENSG00000205649
TCGA cBioPortalHTN3
AceView (NCBI)HTN3
Genatlas (Paris)HTN3
SOURCE (Princeton)HTN3
Genetics Home Reference (NIH)HTN3
Genomic and cartography
GoldenPath hg38 (UCSC)HTN3  -     chr4:70028459-70036538 +  4q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HTN3  -     4q13.3   [Description]    (hg19-Feb_2009)
GoldenPathHTN3 - 4q13.3 [CytoView hg19]  HTN3 - 4q13.3 [CytoView hg38]
ImmunoBaseENSG00000205649
Genome Data Viewer NCBIHTN3 [Mapview hg19]  
OMIM142702   
Gene and transcription
Genbank (Entrez)BC009791 BC095438 BP332860 CB957931 M18372
RefSeq transcript (Entrez)NM_000200
Consensus coding sequences : CCDS (NCBI)HTN3
Gene ExpressionHTN3 [ NCBI-GEO ]   HTN3 [ EBI - ARRAY_EXPRESS ]   HTN3 [ SEEK ]   HTN3 [ MEM ]
Gene Expression Viewer (FireBrowse)HTN3 [ Firebrowse - Broad ]
GenevisibleExpression of HTN3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3347
GTEX Portal (Tissue expression)HTN3
Human Protein AtlasENSG00000205649-HTN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15516   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15516  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15516
PhosPhoSitePlusP15516
Domains : Interpro (EBI)Histatin-3    Histatin/statherin   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)HTN3
SuperfamilyP15516
AlphaFold pdb e-kbP15516   
Human Protein Atlas [tissue]ENSG00000205649-HTN3 [tissue]
HPRD00815
Protein Interaction databases
DIP (DOE-UCLA)P15516
IntAct (EBI)P15516
BioGRIDHTN3
STRING (EMBL)HTN3
ZODIACHTN3
Ontologies - Pathways
QuickGOP15516
Ontology : AmiGOprotein binding  extracellular region  extracellular region  antimicrobial humoral response  biomineral tissue development  killing of cells of other organism  defense response to bacterium  metal ion binding  defense response to fungus  
Ontology : EGO-EBIprotein binding  extracellular region  extracellular region  antimicrobial humoral response  biomineral tissue development  killing of cells of other organism  defense response to bacterium  metal ion binding  defense response to fungus  
Pathways : KEGGSalivary secretion   
NDEx NetworkHTN3
Atlas of Cancer Signalling NetworkHTN3
Wikipedia pathwaysHTN3
Orthology - Evolution
OrthoDB3347
GeneTree (enSembl)ENSG00000205649
Phylogenetic Trees/Animal Genes : TreeFamHTN3
Homologs : HomoloGeneHTN3
Homology/Alignments : Family Browser (UCSC)HTN3
Gene fusions - Rearrangements
Fusion : MitelmanDAB2IP/HTN3 [9q33.2/4q13.3]  
Fusion : MitelmanKCNE2/HTN3 [21q22.11/4q13.3]  
Fusion : QuiverHTN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HTN3
dbVarHTN3
ClinVarHTN3
MonarchHTN3
1000_GenomesHTN3 
Exome Variant ServerHTN3
GNOMAD BrowserENSG00000205649
Varsome BrowserHTN3
ACMGHTN3 variants
VarityP15516
Genomic Variants (DGV)HTN3 [DGVbeta]
DECIPHERHTN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHTN3 
Mutations
ICGC Data PortalHTN3 
TCGA Data PortalHTN3 
Broad Tumor PortalHTN3
OASIS PortalHTN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTN3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHTN3
Mutations and Diseases : HGMDHTN3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHTN3
DgiDB (Drug Gene Interaction Database)HTN3
DoCM (Curated mutations)HTN3
CIViC (Clinical Interpretations of Variants in Cancer)HTN3
Cancer3DHTN3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142702   
Orphanet
DisGeNETHTN3
MedgenHTN3
Genetic Testing Registry HTN3
NextProtP15516 [Medical]
GENETestsHTN3
Target ValidationHTN3
Huge Navigator HTN3 [HugePedia]
ClinGenHTN3
Clinical trials, drugs, therapy
MyCancerGenomeHTN3
Protein Interactions : CTDHTN3
Pharm GKB GenePA29547
PharosP15516
Clinical trialHTN3
Miscellaneous
canSAR (ICR)HTN3
HarmonizomeHTN3
DataMed IndexHTN3
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHTN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:13:12 CEST 2021

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