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HTR1F (5-hydroxytryptamine receptor 1F)

Identity

Alias_names5-hydroxytryptamine (serotonin) receptor 1F
5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
Alias_symbol (synonym)HTR1EL
5-HT1F
Other alias5-HT-1F
5HT6
MR77
HGNC (Hugo) HTR1F
LocusID (NCBI) 3355
Atlas_Id 64465
Location 3p11.1  [Link to chromosome band 3p11]
Location_base_pair Starts at 87982576 and ends at 87993831 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HTR1F   5292
Cards
Entrez_Gene (NCBI)HTR1F  3355  5-hydroxytryptamine receptor 1F
Aliases5-HT-1F; 5-HT1F; 5HT6; HTR1EL; 
MR77
GeneCards (Weizmann)HTR1F
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr3:87982576-87993831 [Contig_View]  HTR1F [Vega]
TCGA cBioPortalHTR1F
AceView (NCBI)HTR1F
Genatlas (Paris)HTR1F
WikiGenes3355
SOURCE (Princeton)HTR1F
Genetics Home Reference (NIH)HTR1F
Genomic and cartography
GoldenPath hg38 (UCSC)HTR1F  -     chr3:87982576-87993831 +  3p11.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HTR1F  -     3p11.1   [Description]    (hg19-Feb_2009)
EnsemblHTR1F - 3p11.1 [CytoView hg19]  HTR1F - 3p11.1 [CytoView hg38]
Mapping of homologs : NCBIHTR1F [Mapview hg19]  HTR1F [Mapview hg38]
OMIM182134   
Gene and transcription
Genbank (Entrez)AF498981 BC069125 BC096838 BX357988 CA942616
RefSeq transcript (Entrez)NM_000866 NM_001322208 NM_001322209 NM_001322210
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HTR1F
Cluster EST : UnigeneHs.248136 [ NCBI ]
CGAP (NCI)Hs.248136
Gene ExpressionHTR1F [ NCBI-GEO ]   HTR1F [ EBI - ARRAY_EXPRESS ]   HTR1F [ SEEK ]   HTR1F [ MEM ]
Gene Expression Viewer (FireBrowse)HTR1F [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3355
GTEX Portal (Tissue expression)HTR1F
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30939   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30939  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30939
Splice isoforms : SwissVarP30939
PhosPhoSitePlusP30939
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)5HT1F_rcpt    5HT_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)HTR1F
DMDM Disease mutations3355
Blocks (Seattle)HTR1F
SuperfamilyP30939
Peptide AtlasP30939
HPRD01637
IPIIPI00028093   IPI00979326   
Protein Interaction databases
DIP (DOE-UCLA)P30939
IntAct (EBI)P30939
BioGRIDHTR1F
STRING (EMBL)HTR1F
ZODIACHTR1F
Ontologies - Pathways
QuickGOP30939
Ontology : AmiGOG-protein coupled serotonin receptor activity  G-protein coupled serotonin receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  chemical synaptic transmission  neurotransmitter receptor activity  serotonin binding  G-protein coupled serotonin receptor signaling pathway  
Ontology : EGO-EBIG-protein coupled serotonin receptor activity  G-protein coupled serotonin receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  chemical synaptic transmission  neurotransmitter receptor activity  serotonin binding  G-protein coupled serotonin receptor signaling pathway  
Pathways : KEGGNeuroactive ligand-receptor interaction    Serotonergic synapse   
NDEx NetworkHTR1F
Atlas of Cancer Signalling NetworkHTR1F
Wikipedia pathwaysHTR1F
Orthology - Evolution
OrthoDB3355
Phylogenetic Trees/Animal Genes : TreeFamHTR1F
HOVERGENP30939
HOGENOMP30939
Homologs : HomoloGeneHTR1F
Homology/Alignments : Family Browser (UCSC)HTR1F
Gene fusions - Rearrangements
Fusion: Tumor Portal HTR1F
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTR1F [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HTR1F
dbVarHTR1F
ClinVarHTR1F
1000_GenomesHTR1F 
Exome Variant ServerHTR1F
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP3355
Genomic Variants (DGV)HTR1F [DGVbeta]
DECIPHERHTR1F [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHTR1F 
Mutations
ICGC Data PortalHTR1F 
TCGA Data PortalHTR1F 
Broad Tumor PortalHTR1F
OASIS PortalHTR1F [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTR1F  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHTR1F
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HTR1F
DgiDB (Drug Gene Interaction Database)HTR1F
DoCM (Curated mutations)HTR1F (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HTR1F (select a term)
intoGenHTR1F
Cancer3DHTR1F(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182134   
Orphanet
MedgenHTR1F
Genetic Testing Registry HTR1F
NextProtP30939 [Medical]
TSGene3355
GENETestsHTR1F
Target ValidationHTR1F
Huge Navigator HTR1F [HugePedia]
snp3D : Map Gene to Disease3355
BioCentury BCIQHTR1F
ClinGenHTR1F
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3355
Chemical/Pharm GKB GenePA29553
Clinical trialHTR1F
Miscellaneous
canSAR (ICR)HTR1F (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHTR1F
EVEXHTR1F
GoPubMedHTR1F
iHOPHTR1F
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:51:06 CET 2017

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