HTR2A (5-hydroxytryptamine (serotonin) receptor 2A)

Identity

Other names	5-HT2A
	HTR2
HGNC	HTR2A
Location	13q14-q21
Location_base_pair	Starts at 46305514 and ends at 46368176 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	HTR2A   5293
Entrez_Gene	HTR2A  3356  5-hydroxytryptamine (serotonin) receptor 2A
	Cards
GeneCards	HTR2A
Ensembl	HTR2A [Search_View]   ENSG00000102468 [Gene_View]
Genatlas	HTR2A
GeneLynx	HTR2A
eGenome	HTR2A
euGene	3356
	Genomic and cartography
GoldenPath	HTR2A  -     chr13:46305514-46368176 -  13q14.2   [Description]    (hg18-March_2006)
Ensembl	HTR2A - 13q14.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	HTR2A
	Gene and transcription
Genbank	A23337 [ ENTREZ ]
Genbank	AA418604 [ ENTREZ ]
Genbank	AF498982 [ ENTREZ ]
Genbank	AK314132 [ ENTREZ ]
Genbank	BC069356 [ ENTREZ ]
RefSeq	NM_000621 [ SRS ]    NM_000621 [ ENTREZ ]
RefSeq	AC_000056 [ SRS ]    AC_000056 [ ENTREZ ]
RefSeq	AC_000145 [ SRS ]    AC_000145 [ ENTREZ ]
RefSeq	NC_000013 [ SRS ]    NC_000013 [ ENTREZ ]
RefSeq	NT_024524 [ SRS ]    NT_024524 [ ENTREZ ]
RefSeq	NW_001838074 [ SRS ]    NW_001838074 [ ENTREZ ]
RefSeq	NW_925473 [ SRS ]    NW_925473 [ ENTREZ ]
AceView	HTR2A AceView - NCBI
Unigene	Hs.654586 [ SRS ]    Hs.654586 [ NCBI ]     HS654586 [ spliceNest ]
Fast-db	5031 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P28223 [ SRS]    P28223 [ EXPASY ]     P28223 [ INTERPRO ]     P28223 [ UNIPROT ]
Prosite	PS00237 G_PROTEIN_RECEP_F1_1 [ SRS ]    PS00237 G_PROTEIN_RECEP_F1_1 [ Expasy ]
Prosite	PS50262 G_PROTEIN_RECEP_F1_2 [ SRS ]    PS50262 G_PROTEIN_RECEP_F1_2 [ Expasy ]
Interpro	IPR000455 5HT2A_rcpt [ SRS ]    IPR000455 5HT2A_rcpt [ EBI ]
Interpro	IPR002231 5HT_rcpt [ SRS ]    IPR002231 5HT_rcpt [ EBI ]
Interpro	IPR000276 GPCR_Rhodpsn [ SRS ]    IPR000276 GPCR_Rhodpsn [ EBI ]
Interpro	IPR017452 GPCR_Rhodpsn_supfam [ SRS ]    IPR017452 GPCR_Rhodpsn_supfam [ EBI ]
CluSTr	P28223
Pfam	PF00001 7tm_1 [ SRS ]    PF00001 7tm_1 [ Sanger ]    pfam00001 [ NCBI-CDD ]
Blocks	P28223
HPRD	01638
	Protein Interaction databases
DIP	P28223
IntAct	P28223
	Polymorphism : SNP, mutations, diseases
OMIM	103780;164230;181500;182135;606788;608516    [ map ]
GENECLINICS	103780;164230;181500;182135;606788;608516
SNP	HTR2A [dbSNP-NCBI]
SNP	NM_000621 [SNP-NCI]
SNP	HTR2A [GeneSNPs - Utah]  HTR2A] [HGBASE - SRS]
HAPMAP	HTR2A [HAPMAP]
HGMD	HTR2A
	General knowledge
Family Browser	HTR2A [UCSC Family Browser]
SOURCE	NM_000621
SMD	Hs.654586
SAGE	Hs.654586
GO	rhodopsin-like receptor activity [Amigo]  rhodopsin-like receptor activity
GO	temperature homeostasis [Amigo]  temperature homeostasis
GO	receptor activity [Amigo]  receptor activity
GO	serotonin receptor activity [Amigo]  serotonin receptor activity
GO	cytoplasm [Amigo]  cytoplasm
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	response to stress [Amigo]  response to stress
GO	signal transduction [Amigo]  signal transduction
GO	serotonin receptor, phospholipase C activating pathway [Amigo]  serotonin receptor, phospholipase C activating pathway
GO	serotonin receptor signaling pathway [Amigo]  serotonin receptor signaling pathway
GO	synaptic transmission [Amigo]  synaptic transmission
GO	aging [Amigo]  aging
GO	memory [Amigo]  memory
GO	cell death [Amigo]  cell death
GO	positive regulation of cell proliferation [Amigo]  positive regulation of cell proliferation
GO	regulation of dopamine secretion [Amigo]  regulation of dopamine secretion
GO	sensory perception of pain [Amigo]  sensory perception of pain
GO	dendrite [Amigo]  dendrite
GO	sleep [Amigo]  sleep
GO	protein complex binding [Amigo]  protein complex binding
GO	response to drug [Amigo]  response to drug
GO	negative regulation of potassium ion transport [Amigo]  negative regulation of potassium ion transport
GO	positive regulation of MAP kinase activity [Amigo]  positive regulation of MAP kinase activity
GO	positive regulation of vasoconstriction [Amigo]  positive regulation of vasoconstriction
GO	negative regulation of synaptic transmission, glutamatergic [Amigo]  negative regulation of synaptic transmission, glutamatergic
KEGG	Calcium signaling pathway
KEGG	Neuroactive ligand-receptor interaction
KEGG	Gap junction
PubGene	HTR2A
TreeFam	HTR2A
CTD	3356 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	HTR2A Related clones (RZPD - Berlin)
	PubMed
PubMed	287 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:37:30 2008