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HTR3B (5-hydroxytryptamine receptor 3B)

Identity

Alias (NCBI)5-HT3B
HGNC (Hugo) HTR3B
HGNC Alias symb5-HT3B
HGNC Previous name5-hydroxytryptamine (serotonin) receptor 3B
 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
LocusID (NCBI) 9177
Atlas_Id 64468
Location 11q23.2  [Link to chromosome band 11q23]
Location_base_pair Starts at 113904796 and ends at 113946561 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)HTR3B   5298
Cards
Entrez_Gene (NCBI)HTR3B    5-hydroxytryptamine receptor 3B
Aliases5-HT3B
GeneCards (Weizmann)HTR3B
Ensembl hg19 (Hinxton)ENSG00000149305 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149305 [Gene_View]  ENSG00000149305 [Sequence]  chr11:113904796-113946561 [Contig_View]  HTR3B [Vega]
ICGC DataPortalENSG00000149305
TCGA cBioPortalHTR3B
AceView (NCBI)HTR3B
Genatlas (Paris)HTR3B
SOURCE (Princeton)HTR3B
Genetics Home Reference (NIH)HTR3B
Genomic and cartography
GoldenPath hg38 (UCSC)HTR3B  -     chr11:113904796-113946561 +  11q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HTR3B  -     11q23.2   [Description]    (hg19-Feb_2009)
GoldenPathHTR3B - 11q23.2 [CytoView hg19]  HTR3B - 11q23.2 [CytoView hg38]
ImmunoBaseENSG00000149305
genome Data Viewer NCBIHTR3B [Mapview hg19]  
OMIM604654   
Gene and transcription
Genbank (Entrez)AF080582 AF169255 AK314268 AM293589
RefSeq transcript (Entrez)NM_001363563 NM_006028
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HTR3B
Alternative Splicing GalleryENSG00000149305
Gene ExpressionHTR3B [ NCBI-GEO ]   HTR3B [ EBI - ARRAY_EXPRESS ]   HTR3B [ SEEK ]   HTR3B [ MEM ]
Gene Expression Viewer (FireBrowse)HTR3B [ Firebrowse - Broad ]
GenevisibleExpression of HTR3B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9177
GTEX Portal (Tissue expression)HTR3B
Human Protein AtlasENSG00000149305-HTR3B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95264   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95264  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95264
Splice isoforms : SwissVarO95264
PhosPhoSitePlusO95264
Domains : Interpro (EBI)5HT3_rcpt    5HT3_rcpt_B    Neur_chan_lig-bd    Neur_chan_lig-bd_sf    Neur_channel    Neuro-gated_channel_TM_sf    Neurotrans-gated_channel_TM   
Domain families : Pfam (Sanger)Neur_chan_LBD (PF02931)    Neur_chan_memb (PF02932)   
Domain families : Pfam (NCBI)pfam02931    pfam02932   
Conserved Domain (NCBI)HTR3B
Blocks (Seattle)HTR3B
SuperfamilyO95264
Human Protein Atlas [tissue]ENSG00000149305-HTR3B [tissue]
Peptide AtlasO95264
HPRD06875
IPIIPI00005673   IPI00876974   IPI01015910   
Protein Interaction databases
DIP (DOE-UCLA)O95264
IntAct (EBI)O95264
BioGRIDHTR3B
STRING (EMBL)HTR3B
ZODIACHTR3B
Ontologies - Pathways
QuickGOO95264
Ontology : AmiGOtransmembrane signaling receptor activity  extracellular ligand-gated ion channel activity  plasma membrane  integral component of plasma membrane  signal transduction  serotonin receptor signaling pathway  chemical synaptic transmission  chemical synaptic transmission  cell surface  serotonin-gated cation-selective channel activity  ion transmembrane transport  regulation of membrane potential  neuron projection  synapse  postsynaptic membrane  nervous system process  serotonin-activated cation-selective channel complex  
Ontology : EGO-EBItransmembrane signaling receptor activity  extracellular ligand-gated ion channel activity  plasma membrane  integral component of plasma membrane  signal transduction  serotonin receptor signaling pathway  chemical synaptic transmission  chemical synaptic transmission  cell surface  serotonin-gated cation-selective channel activity  ion transmembrane transport  regulation of membrane potential  neuron projection  synapse  postsynaptic membrane  nervous system process  serotonin-activated cation-selective channel complex  
NDEx NetworkHTR3B
Atlas of Cancer Signalling NetworkHTR3B
Wikipedia pathwaysHTR3B
Orthology - Evolution
OrthoDB9177
GeneTree (enSembl)ENSG00000149305
Phylogenetic Trees/Animal Genes : TreeFamHTR3B
HOGENOMO95264
Homologs : HomoloGeneHTR3B
Homology/Alignments : Family Browser (UCSC)HTR3B
Gene fusions - Rearrangements
Fusion : QuiverHTR3B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTR3B [hg38]
dbVarHTR3B
ClinVarHTR3B
MonarchHTR3B
1000_GenomesHTR3B 
Exome Variant ServerHTR3B
GNOMAD BrowserENSG00000149305
Varsome BrowserHTR3B
Genomic Variants (DGV)HTR3B [DGVbeta]
DECIPHERHTR3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHTR3B 
Mutations
ICGC Data PortalHTR3B 
TCGA Data PortalHTR3B 
Broad Tumor PortalHTR3B
OASIS PortalHTR3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTR3B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHTR3B
Mutations and Diseases : HGMDHTR3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)University of Heidelberg Serotonin receptor variant database
BioMutasearch HTR3B
DgiDB (Drug Gene Interaction Database)HTR3B
DoCM (Curated mutations)HTR3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HTR3B (select a term)
intoGenHTR3B
Cancer3DHTR3B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604654   
Orphanet
DisGeNETHTR3B
MedgenHTR3B
Genetic Testing Registry HTR3B
NextProtO95264 [Medical]
GENETestsHTR3B
Target ValidationHTR3B
Huge Navigator HTR3B [HugePedia]
ClinGenHTR3B
Clinical trials, drugs, therapy
MyCancerGenomeHTR3B
Protein Interactions : CTD
Pharm GKB GenePA29556
Clinical trialHTR3B
Miscellaneous
canSAR (ICR)HTR3B (select the gene name)
HarmonizomeHTR3B
DataMed IndexHTR3B
Probes
Litterature
PubMed76 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHTR3B
EVEXHTR3B
GoPubMedHTR3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 16:57:25 CET 2020

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