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HTR3B (5-hydroxytryptamine receptor 3B)

Identity

Alias_names5-hydroxytryptamine (serotonin) receptor 3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
Alias_symbol (synonym)5-HT3B
Other alias
HGNC (Hugo) HTR3B
LocusID (NCBI) 9177
Atlas_Id 64468
Location 11q23.2  [Link to chromosome band 11q23]
Location_base_pair Starts at 113904796 and ends at 113946561 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HTR3B   5298
Cards
Entrez_Gene (NCBI)HTR3B  9177  5-hydroxytryptamine receptor 3B
Aliases5-HT3B
GeneCards (Weizmann)HTR3B
Ensembl hg19 (Hinxton)ENSG00000149305 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149305 [Gene_View]  chr11:113904796-113946561 [Contig_View]  HTR3B [Vega]
ICGC DataPortalENSG00000149305
TCGA cBioPortalHTR3B
AceView (NCBI)HTR3B
Genatlas (Paris)HTR3B
WikiGenes9177
SOURCE (Princeton)HTR3B
Genetics Home Reference (NIH)HTR3B
Genomic and cartography
GoldenPath hg38 (UCSC)HTR3B  -     chr11:113904796-113946561 +  11q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HTR3B  -     11q23.2   [Description]    (hg19-Feb_2009)
EnsemblHTR3B - 11q23.2 [CytoView hg19]  HTR3B - 11q23.2 [CytoView hg38]
Mapping of homologs : NCBIHTR3B [Mapview hg19]  HTR3B [Mapview hg38]
OMIM604654   
Gene and transcription
Genbank (Entrez)AF080582 AF169255 AK314268 AM293589 BC141515
RefSeq transcript (Entrez)NM_006028
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HTR3B
Cluster EST : UnigeneHs.241377 [ NCBI ]
CGAP (NCI)Hs.241377
Alternative Splicing GalleryENSG00000149305
Gene ExpressionHTR3B [ NCBI-GEO ]   HTR3B [ EBI - ARRAY_EXPRESS ]   HTR3B [ SEEK ]   HTR3B [ MEM ]
Gene Expression Viewer (FireBrowse)HTR3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9177
GTEX Portal (Tissue expression)HTR3B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95264   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95264  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95264
Splice isoforms : SwissVarO95264
PhosPhoSitePlusO95264
Domains : Interpro (EBI)5HT3_rcpt    5HT3_rcpt_B    Acetylcholine_rcpt_TM    Neur_chan_lig-bd    Neur_channel    Neurotrans-gated_channel_TM   
Domain families : Pfam (Sanger)Neur_chan_LBD (PF02931)    Neur_chan_memb (PF02932)   
Domain families : Pfam (NCBI)pfam02931    pfam02932   
Conserved Domain (NCBI)HTR3B
DMDM Disease mutations9177
Blocks (Seattle)HTR3B
SuperfamilyO95264
Human Protein AtlasENSG00000149305
Peptide AtlasO95264
HPRD06875
IPIIPI00005673   IPI00876974   IPI01015910   
Protein Interaction databases
DIP (DOE-UCLA)O95264
IntAct (EBI)O95264
FunCoupENSG00000149305
BioGRIDHTR3B
STRING (EMBL)HTR3B
ZODIACHTR3B
Ontologies - Pathways
QuickGOO95264
Ontology : AmiGOG-protein coupled serotonin receptor activity  plasma membrane  integral component of plasma membrane  serotonin receptor signaling pathway  cell surface  serotonin-gated cation-selective channel activity  ion transmembrane transport  postsynaptic membrane  cation transmembrane transport  G-protein coupled serotonin receptor signaling pathway  serotonin-activated cation-selective channel complex  
Ontology : EGO-EBIG-protein coupled serotonin receptor activity  plasma membrane  integral component of plasma membrane  serotonin receptor signaling pathway  cell surface  serotonin-gated cation-selective channel activity  ion transmembrane transport  postsynaptic membrane  cation transmembrane transport  G-protein coupled serotonin receptor signaling pathway  serotonin-activated cation-selective channel complex  
Pathways : KEGGSerotonergic synapse   
NDEx NetworkHTR3B
Atlas of Cancer Signalling NetworkHTR3B
Wikipedia pathwaysHTR3B
Orthology - Evolution
OrthoDB9177
GeneTree (enSembl)ENSG00000149305
Phylogenetic Trees/Animal Genes : TreeFamHTR3B
HOVERGENO95264
HOGENOMO95264
Homologs : HomoloGeneHTR3B
Homology/Alignments : Family Browser (UCSC)HTR3B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTR3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HTR3B
dbVarHTR3B
ClinVarHTR3B
1000_GenomesHTR3B 
Exome Variant ServerHTR3B
ExAC (Exome Aggregation Consortium)HTR3B (select the gene name)
Genetic variants : HAPMAP9177
Genomic Variants (DGV)HTR3B [DGVbeta]
DECIPHERHTR3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHTR3B 
Mutations
ICGC Data PortalHTR3B 
TCGA Data PortalHTR3B 
Broad Tumor PortalHTR3B
OASIS PortalHTR3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTR3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHTR3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)University of Heidelberg Serotonin receptor variant database
BioMutasearch HTR3B
DgiDB (Drug Gene Interaction Database)HTR3B
DoCM (Curated mutations)HTR3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HTR3B (select a term)
intoGenHTR3B
Cancer3DHTR3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604654   
Orphanet
MedgenHTR3B
Genetic Testing Registry HTR3B
NextProtO95264 [Medical]
TSGene9177
GENETestsHTR3B
Target ValidationHTR3B
Huge Navigator HTR3B [HugePedia]
snp3D : Map Gene to Disease9177
BioCentury BCIQHTR3B
ClinGenHTR3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9177
Chemical/Pharm GKB GenePA29556
Clinical trialHTR3B
Miscellaneous
canSAR (ICR)HTR3B (select the gene name)
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHTR3B
EVEXHTR3B
GoPubMedHTR3B
iHOPHTR3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:52:59 CEST 2017

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