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HTR3C (5-hydroxytryptamine (serotonin) receptor 3C, ionotropic)

Identity

Alias_names5-hydroxytryptamine (serotonin) receptor 3, family member C
5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
Other alias-
HGNC (Hugo) HTR3C
LocusID (NCBI) 170572
Atlas_Id 64469
Location 3q27.1  [Link to chromosome band 3q27]
Location_base_pair Starts at 183770835 and ends at 183778461 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ECE2 (3q27.1) / HTR3C (3q27.1)PRRC2B (9q34.13) / HTR3C (3q27.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HTR3C   24003
Cards
Entrez_Gene (NCBI)HTR3C  170572  5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
Aliases
GeneCards (Weizmann)HTR3C
Ensembl hg19 (Hinxton)ENSG00000178084 [Gene_View]  chr3:183770835-183778461 [Contig_View]  HTR3C [Vega]
Ensembl hg38 (Hinxton)ENSG00000178084 [Gene_View]  chr3:183770835-183778461 [Contig_View]  HTR3C [Vega]
ICGC DataPortalENSG00000178084
TCGA cBioPortalHTR3C
AceView (NCBI)HTR3C
Genatlas (Paris)HTR3C
WikiGenes170572
SOURCE (Princeton)HTR3C
Genetics Home Reference (NIH)HTR3C
Genomic and cartography
GoldenPath hg19 (UCSC)HTR3C  -     chr3:183770835-183778461 +  3q27.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HTR3C  -     3q27.1   [Description]    (hg38-Dec_2013)
EnsemblHTR3C - 3q27.1 [CytoView hg19]  HTR3C - 3q27.1 [CytoView hg38]
Mapping of homologs : NCBIHTR3C [Mapview hg19]  HTR3C [Mapview hg38]
OMIM610121   
Gene and transcription
Genbank (Entrez)AF459285 BC131799
RefSeq transcript (Entrez)NM_130770
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_012749 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)HTR3C
Cluster EST : UnigeneHs.632579 [ NCBI ]
CGAP (NCI)Hs.632579
Alternative Splicing GalleryENSG00000178084
Gene ExpressionHTR3C [ NCBI-GEO ]   HTR3C [ EBI - ARRAY_EXPRESS ]   HTR3C [ SEEK ]   HTR3C [ MEM ]
Gene Expression Viewer (FireBrowse)HTR3C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)170572
GTEX Portal (Tissue expression)HTR3C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WXA8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WXA8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WXA8
Splice isoforms : SwissVarQ8WXA8
PhosPhoSitePlusQ8WXA8
Domaine pattern : Prosite (Expaxy)NEUROTR_ION_CHANNEL (PS00236)   
Domains : Interpro (EBI)Acetylcholine_rcpt_TM    Neur_chan_lig-bd    Neur_channel    Neurotrans-gated_channel_TM    Neurotransmitter_ion_chnl_CS   
Domain families : Pfam (Sanger)Neur_chan_LBD (PF02931)    Neur_chan_memb (PF02932)   
Domain families : Pfam (NCBI)pfam02931    pfam02932   
Conserved Domain (NCBI)HTR3C
DMDM Disease mutations170572
Blocks (Seattle)HTR3C
SuperfamilyQ8WXA8
Human Protein AtlasENSG00000178084
Peptide AtlasQ8WXA8
HPRD17120
IPIIPI00103496   
Protein Interaction databases
DIP (DOE-UCLA)Q8WXA8
IntAct (EBI)Q8WXA8
FunCoupENSG00000178084
BioGRIDHTR3C
STRING (EMBL)HTR3C
ZODIACHTR3C
Ontologies - Pathways
QuickGOQ8WXA8
Ontology : AmiGOserotonin receptor activity  extracellular ligand-gated ion channel activity  plasma membrane  serotonin receptor signaling pathway  integral component of membrane  ion transmembrane transport  transmembrane transport  
Ontology : EGO-EBIserotonin receptor activity  extracellular ligand-gated ion channel activity  plasma membrane  serotonin receptor signaling pathway  integral component of membrane  ion transmembrane transport  transmembrane transport  
Pathways : KEGGSerotonergic synapse   
NDEx NetworkHTR3C
Atlas of Cancer Signalling NetworkHTR3C
Wikipedia pathwaysHTR3C
Orthology - Evolution
OrthoDB170572
GeneTree (enSembl)ENSG00000178084
Phylogenetic Trees/Animal Genes : TreeFamHTR3C
HOVERGENQ8WXA8
HOGENOMQ8WXA8
Homologs : HomoloGeneHTR3C
Homology/Alignments : Family Browser (UCSC)HTR3C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTR3C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HTR3C
dbVarHTR3C
ClinVarHTR3C
1000_GenomesHTR3C 
Exome Variant ServerHTR3C
ExAC (Exome Aggregation Consortium)HTR3C (select the gene name)
Genetic variants : HAPMAP170572
Genomic Variants (DGV)HTR3C [DGVbeta]
DECIPHER (Syndromes)3:183770835-183778461  ENSG00000178084
CONAN: Copy Number AnalysisHTR3C 
Mutations
ICGC Data PortalHTR3C 
TCGA Data PortalHTR3C 
Broad Tumor PortalHTR3C
OASIS PortalHTR3C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTR3C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHTR3C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)University of Heidelberg Serotonin receptor variant database
BioMutasearch HTR3C
DgiDB (Drug Gene Interaction Database)HTR3C
DoCM (Curated mutations)HTR3C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HTR3C (select a term)
intoGenHTR3C
Cancer3DHTR3C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610121   
Orphanet
MedgenHTR3C
Genetic Testing Registry HTR3C
NextProtQ8WXA8 [Medical]
TSGene170572
GENETestsHTR3C
Huge Navigator HTR3C [HugePedia]
snp3D : Map Gene to Disease170572
BioCentury BCIQHTR3C
ClinGenHTR3C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD170572
Chemical/Pharm GKB GenePA134925741
Clinical trialHTR3C
Miscellaneous
canSAR (ICR)HTR3C (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHTR3C
EVEXHTR3C
GoPubMedHTR3C
iHOPHTR3C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:08:23 CET 2017

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