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HTR5A (5-hydroxytryptamine receptor 5A)

Identity

Alias_names5-hydroxytryptamine (serotonin) receptor 5A
5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
Alias_symbol (synonym)5-HT5A
Other alias
HGNC (Hugo) HTR5A
LocusID (NCBI) 3361
Atlas_Id 64472
Location 7q36.2  [Link to chromosome band 7q36]
Location_base_pair Starts at 155070324 and ends at 155087392 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HTR5A   5300
LRG (Locus Reference Genomic)LRG_1057
Cards
Entrez_Gene (NCBI)HTR5A  3361  5-hydroxytryptamine receptor 5A
Aliases5-HT5A
GeneCards (Weizmann)HTR5A
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr7:155070324-155087392 [Contig_View]  HTR5A [Vega]
TCGA cBioPortalHTR5A
AceView (NCBI)HTR5A
Genatlas (Paris)HTR5A
WikiGenes3361
SOURCE (Princeton)HTR5A
Genetics Home Reference (NIH)HTR5A
Genomic and cartography
GoldenPath hg38 (UCSC)HTR5A  -     chr7:155070324-155087392 +  7q36.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HTR5A  -     7q36.2   [Description]    (hg19-Feb_2009)
EnsemblHTR5A - 7q36.2 [CytoView hg19]  HTR5A - 7q36.2 [CytoView hg38]
Mapping of homologs : NCBIHTR5A [Mapview hg19]  HTR5A [Mapview hg38]
OMIM601305   
Gene and transcription
Genbank (Entrez)AF498985 AK094255 AK310284 BC112021 BC113468
RefSeq transcript (Entrez)NM_024012
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HTR5A
Cluster EST : UnigeneHs.744621 [ NCBI ]
CGAP (NCI)Hs.744621
Gene ExpressionHTR5A [ NCBI-GEO ]   HTR5A [ EBI - ARRAY_EXPRESS ]   HTR5A [ SEEK ]   HTR5A [ MEM ]
Gene Expression Viewer (FireBrowse)HTR5A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3361
GTEX Portal (Tissue expression)HTR5A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP47898   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP47898  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP47898
Splice isoforms : SwissVarP47898
PhosPhoSitePlusP47898
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)5HT5A_rcpt    5HT_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)HTR5A
DMDM Disease mutations3361
Blocks (Seattle)HTR5A
SuperfamilyP47898
Peptide AtlasP47898
HPRD03198
IPIIPI00026666   
Protein Interaction databases
DIP (DOE-UCLA)P47898
IntAct (EBI)P47898
BioGRIDHTR5A
STRING (EMBL)HTR5A
ZODIACHTR5A
Ontologies - Pathways
QuickGOP47898
Ontology : AmiGOG-protein coupled serotonin receptor activity  rough endoplasmic reticulum  Golgi apparatus  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting serotonin receptor signaling pathway  cAMP-mediated signaling  hippocampus development  dendrite  neurotransmitter receptor activity  response to estradiol  perikaryon  serotonin binding  
Ontology : EGO-EBIG-protein coupled serotonin receptor activity  rough endoplasmic reticulum  Golgi apparatus  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting serotonin receptor signaling pathway  cAMP-mediated signaling  hippocampus development  dendrite  neurotransmitter receptor activity  response to estradiol  perikaryon  serotonin binding  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Serotonergic synapse   
NDEx NetworkHTR5A
Atlas of Cancer Signalling NetworkHTR5A
Wikipedia pathwaysHTR5A
Orthology - Evolution
OrthoDB3361
Phylogenetic Trees/Animal Genes : TreeFamHTR5A
HOVERGENP47898
HOGENOMP47898
Homologs : HomoloGeneHTR5A
Homology/Alignments : Family Browser (UCSC)HTR5A
Gene fusions - Rearrangements
Tumor Fusion PortalHTR5A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTR5A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HTR5A
dbVarHTR5A
ClinVarHTR5A
1000_GenomesHTR5A 
Exome Variant ServerHTR5A
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP3361
Genomic Variants (DGV)HTR5A [DGVbeta]
DECIPHERHTR5A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHTR5A 
Mutations
ICGC Data PortalHTR5A 
TCGA Data PortalHTR5A 
Broad Tumor PortalHTR5A
OASIS PortalHTR5A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTR5A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHTR5A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HTR5A
DgiDB (Drug Gene Interaction Database)HTR5A
DoCM (Curated mutations)HTR5A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HTR5A (select a term)
intoGenHTR5A
Cancer3DHTR5A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601305   
Orphanet
DisGeNETHTR5A
MedgenHTR5A
Genetic Testing Registry HTR5A
NextProtP47898 [Medical]
TSGene3361
GENETestsHTR5A
Target ValidationHTR5A
Huge Navigator HTR5A [HugePedia]
snp3D : Map Gene to Disease3361
BioCentury BCIQHTR5A
ClinGenHTR5A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3361
Chemical/Pharm GKB GenePA29558
Clinical trialHTR5A
Miscellaneous
canSAR (ICR)HTR5A (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHTR5A
EVEXHTR5A
GoPubMedHTR5A
iHOPHTR5A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:16:15 CET 2017

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