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HTR6 (5-hydroxytryptamine receptor 6)

Identity

Alias_names5-hydroxytryptamine (serotonin) receptor 6
5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
Alias_symbol (synonym)5-HT6
5-HT6R
Other alias
HGNC (Hugo) HTR6
LocusID (NCBI) 3362
Atlas_Id 64474
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 19665287 and ends at 19680966 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HTR6   5301
Cards
Entrez_Gene (NCBI)HTR6  3362  5-hydroxytryptamine receptor 6
Aliases5-HT6; 5-HT6R
GeneCards (Weizmann)HTR6
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr1:19665287-19680966 [Contig_View]  HTR6 [Vega]
TCGA cBioPortalHTR6
AceView (NCBI)HTR6
Genatlas (Paris)HTR6
WikiGenes3362
SOURCE (Princeton)HTR6
Genetics Home Reference (NIH)HTR6
Genomic and cartography
GoldenPath hg38 (UCSC)HTR6  -     chr1:19665287-19680966 +  1p36.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HTR6  -     1p36.13   [Description]    (hg19-Feb_2009)
EnsemblHTR6 - 1p36.13 [CytoView hg19]  HTR6 - 1p36.13 [CytoView hg38]
Mapping of homologs : NCBIHTR6 [Mapview hg19]  HTR6 [Mapview hg38]
OMIM601109   
Gene and transcription
Genbank (Entrez)AB209129 AF007141 AY429105 BC074995 BC074996
RefSeq transcript (Entrez)NM_000871
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HTR6
Cluster EST : UnigeneHs.22180 [ NCBI ]
CGAP (NCI)Hs.22180
Gene ExpressionHTR6 [ NCBI-GEO ]   HTR6 [ EBI - ARRAY_EXPRESS ]   HTR6 [ SEEK ]   HTR6 [ MEM ]
Gene Expression Viewer (FireBrowse)HTR6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3362
GTEX Portal (Tissue expression)HTR6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50406   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50406  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50406
Splice isoforms : SwissVarP50406
PhosPhoSitePlusP50406
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)HTR6
DMDM Disease mutations3362
Blocks (Seattle)HTR6
SuperfamilyP50406
Peptide AtlasP50406
HPRD03066
IPIIPI00032009   
Protein Interaction databases
DIP (DOE-UCLA)P50406
IntAct (EBI)P50406
BioGRIDHTR6
STRING (EMBL)HTR6
ZODIACHTR6
Ontologies - Pathways
QuickGOP50406
Ontology : AmiGOhistamine receptor activity  G-protein coupled serotonin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cilium  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  chemical synaptic transmission  cerebral cortex cell migration  neurotransmitter receptor activity  positive regulation of TOR signaling  G-protein coupled serotonin receptor signaling pathway  
Ontology : EGO-EBIhistamine receptor activity  G-protein coupled serotonin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cilium  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  chemical synaptic transmission  cerebral cortex cell migration  neurotransmitter receptor activity  positive regulation of TOR signaling  G-protein coupled serotonin receptor signaling pathway  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Serotonergic synapse   
NDEx NetworkHTR6
Atlas of Cancer Signalling NetworkHTR6
Wikipedia pathwaysHTR6
Orthology - Evolution
OrthoDB3362
Phylogenetic Trees/Animal Genes : TreeFamHTR6
HOVERGENP50406
HOGENOMP50406
Homologs : HomoloGeneHTR6
Homology/Alignments : Family Browser (UCSC)HTR6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTR6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HTR6
dbVarHTR6
ClinVarHTR6
1000_GenomesHTR6 
Exome Variant ServerHTR6
ExAC (Exome Aggregation Consortium)HTR6 (select the gene name)
Genetic variants : HAPMAP3362
Genomic Variants (DGV)HTR6 [DGVbeta]
DECIPHERHTR6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHTR6 
Mutations
ICGC Data PortalHTR6 
TCGA Data PortalHTR6 
Broad Tumor PortalHTR6
OASIS PortalHTR6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTR6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHTR6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HTR6
DgiDB (Drug Gene Interaction Database)HTR6
DoCM (Curated mutations)HTR6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HTR6 (select a term)
intoGenHTR6
Cancer3DHTR6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601109   
Orphanet
MedgenHTR6
Genetic Testing Registry HTR6
NextProtP50406 [Medical]
TSGene3362
GENETestsHTR6
Target ValidationHTR6
Huge Navigator HTR6 [HugePedia]
snp3D : Map Gene to Disease3362
BioCentury BCIQHTR6
ClinGenHTR6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3362
Chemical/Pharm GKB GenePA29560
Clinical trialHTR6
Miscellaneous
canSAR (ICR)HTR6 (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHTR6
EVEXHTR6
GoPubMedHTR6
iHOPHTR6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:53:01 CEST 2017

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