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HTR7 (5-hydroxytryptamine receptor 7)

Identity

Alias (NCBI)5-HT7
HGNC (Hugo) HTR7
HGNC Alias symb5-HT7
HGNC Previous name5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
LocusID (NCBI) 3363
Atlas_Id 64475
Location 10q23.31  [Link to chromosome band 10q23]
Location_base_pair Starts at 90740823 and ends at 90858039 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HTR7   5302
Cards
Entrez_Gene (NCBI)HTR7    5-hydroxytryptamine receptor 7
Aliases5-HT7
GeneCards (Weizmann)HTR7
Ensembl hg19 (Hinxton)ENSG00000148680 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148680 [Gene_View]  ENSG00000148680 [Sequence]  chr10:90740823-90858039 [Contig_View]  HTR7 [Vega]
ICGC DataPortalENSG00000148680
TCGA cBioPortalHTR7
AceView (NCBI)HTR7
Genatlas (Paris)HTR7
SOURCE (Princeton)HTR7
Genetics Home Reference (NIH)HTR7
Genomic and cartography
GoldenPath hg38 (UCSC)HTR7  -     chr10:90740823-90858039 -  10q23.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HTR7  -     10q23.31   [Description]    (hg19-Feb_2009)
GoldenPathHTR7 - 10q23.31 [CytoView hg19]  HTR7 - 10q23.31 [CytoView hg38]
ImmunoBaseENSG00000148680
Genome Data Viewer NCBIHTR7 [Mapview hg19]  
OMIM182137   
Gene and transcription
Genbank (Entrez)AB451482 AK292606 AY493988 BC047526 BG108256
RefSeq transcript (Entrez)NM_000872 NM_019859 NM_019860
Consensus coding sequences : CCDS (NCBI)HTR7
Gene ExpressionHTR7 [ NCBI-GEO ]   HTR7 [ EBI - ARRAY_EXPRESS ]   HTR7 [ SEEK ]   HTR7 [ MEM ]
Gene Expression Viewer (FireBrowse)HTR7 [ Firebrowse - Broad ]
GenevisibleExpression of HTR7 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3363
GTEX Portal (Tissue expression)HTR7
Human Protein AtlasENSG00000148680-HTR7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP34969   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP34969  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP34969
PhosPhoSitePlusP34969
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)5HT_7_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)HTR7
SuperfamilyP34969
AlphaFold pdb e-kbP34969   
Human Protein Atlas [tissue]ENSG00000148680-HTR7 [tissue]
HPRD01639
Protein Interaction databases
DIP (DOE-UCLA)P34969
IntAct (EBI)P34969
BioGRIDHTR7
STRING (EMBL)HTR7
ZODIACHTR7
Ontologies - Pathways
QuickGOP34969
Ontology : AmiGOnegative regulation of inflammatory response to antigenic stimulus  G protein-coupled serotonin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  smooth muscle contraction  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  chemical synaptic transmission  circadian rhythm  blood circulation  dendrite  neurotransmitter receptor activity  trans-Golgi network membrane  vasoconstriction  synapse  G protein-coupled serotonin receptor signaling pathway  
Ontology : EGO-EBInegative regulation of inflammatory response to antigenic stimulus  G protein-coupled serotonin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  smooth muscle contraction  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  chemical synaptic transmission  circadian rhythm  blood circulation  dendrite  neurotransmitter receptor activity  trans-Golgi network membrane  vasoconstriction  synapse  G protein-coupled serotonin receptor signaling pathway  
Pathways : KEGGNeuroactive ligand-receptor interaction    Calcium signaling pathway   
NDEx NetworkHTR7
Atlas of Cancer Signalling NetworkHTR7
Wikipedia pathwaysHTR7
Orthology - Evolution
OrthoDB3363
GeneTree (enSembl)ENSG00000148680
Phylogenetic Trees/Animal Genes : TreeFamHTR7
Homologs : HomoloGeneHTR7
Homology/Alignments : Family Browser (UCSC)HTR7
Gene fusions - Rearrangements
Fusion : QuiverHTR7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTR7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HTR7
dbVarHTR7
ClinVarHTR7
MonarchHTR7
1000_GenomesHTR7 
Exome Variant ServerHTR7
GNOMAD BrowserENSG00000148680
Varsome BrowserHTR7
ACMGHTR7 variants
VarityP34969
Genomic Variants (DGV)HTR7 [DGVbeta]
DECIPHERHTR7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHTR7 
Mutations
ICGC Data PortalHTR7 
TCGA Data PortalHTR7 
Broad Tumor PortalHTR7
OASIS PortalHTR7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTR7  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHTR7
Mutations and Diseases : HGMDHTR7
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHTR7
DgiDB (Drug Gene Interaction Database)HTR7
DoCM (Curated mutations)HTR7
CIViC (Clinical Interpretations of Variants in Cancer)HTR7
Cancer3DHTR7
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182137   
Orphanet
DisGeNETHTR7
MedgenHTR7
Genetic Testing Registry HTR7
NextProtP34969 [Medical]
GENETestsHTR7
Target ValidationHTR7
Huge Navigator HTR7 [HugePedia]
ClinGenHTR7
Clinical trials, drugs, therapy
MyCancerGenomeHTR7
Protein Interactions : CTDHTR7
Pharm GKB GenePA29561
PharosP34969
Clinical trialHTR7
Miscellaneous
canSAR (ICR)HTR7
HarmonizomeHTR7
DataMed IndexHTR7
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHTR7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:53:21 CEST 2021

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