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HTR7 (5-hydroxytryptamine receptor 7)

Identity

Alias_names5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
Alias_symbol (synonym)5-HT7
Other alias
HGNC (Hugo) HTR7
LocusID (NCBI) 3363
Atlas_Id 64475
Location 10q23.31  [Link to chromosome band 10q23]
Location_base_pair Starts at 90740819 and ends at 90857914 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HTR7   5302
Cards
Entrez_Gene (NCBI)HTR7  3363  5-hydroxytryptamine receptor 7
Aliases5-HT7
GeneCards (Weizmann)HTR7
Ensembl hg19 (Hinxton)ENSG00000148680 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148680 [Gene_View]  chr10:90740819-90857914 [Contig_View]  HTR7 [Vega]
ICGC DataPortalENSG00000148680
TCGA cBioPortalHTR7
AceView (NCBI)HTR7
Genatlas (Paris)HTR7
WikiGenes3363
SOURCE (Princeton)HTR7
Genetics Home Reference (NIH)HTR7
Genomic and cartography
GoldenPath hg38 (UCSC)HTR7  -     chr10:90740819-90857914 -  10q23.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HTR7  -     10q23.31   [Description]    (hg19-Feb_2009)
EnsemblHTR7 - 10q23.31 [CytoView hg19]  HTR7 - 10q23.31 [CytoView hg38]
Mapping of homologs : NCBIHTR7 [Mapview hg19]  HTR7 [Mapview hg38]
OMIM182137   
Gene and transcription
Genbank (Entrez)AB451482 AK292606 AY493988 BC047526 BG108256
RefSeq transcript (Entrez)NM_000872 NM_019859 NM_019860
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HTR7
Cluster EST : UnigeneHs.73739 [ NCBI ]
CGAP (NCI)Hs.73739
Alternative Splicing GalleryENSG00000148680
Gene ExpressionHTR7 [ NCBI-GEO ]   HTR7 [ EBI - ARRAY_EXPRESS ]   HTR7 [ SEEK ]   HTR7 [ MEM ]
Gene Expression Viewer (FireBrowse)HTR7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3363
GTEX Portal (Tissue expression)HTR7
Human Protein AtlasENSG00000148680-HTR7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP34969   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP34969  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP34969
Splice isoforms : SwissVarP34969
PhosPhoSitePlusP34969
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)5HT_7_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)HTR7
DMDM Disease mutations3363
Blocks (Seattle)HTR7
SuperfamilyP34969
Human Protein Atlas [tissue]ENSG00000148680-HTR7 [tissue]
Peptide AtlasP34969
HPRD01639
IPIIPI00003048   IPI00553192   IPI00015395   IPI00477724   
Protein Interaction databases
DIP (DOE-UCLA)P34969
IntAct (EBI)P34969
FunCoupENSG00000148680
BioGRIDHTR7
STRING (EMBL)HTR7
ZODIACHTR7
Ontologies - Pathways
QuickGOP34969
Ontology : AmiGOG-protein coupled serotonin receptor activity  plasma membrane  integral component of plasma membrane  smooth muscle contraction  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting serotonin receptor signaling pathway  chemical synaptic transmission  circadian rhythm  blood circulation  neurotransmitter receptor activity  vasoconstriction  serotonin binding  
Ontology : EGO-EBIG-protein coupled serotonin receptor activity  plasma membrane  integral component of plasma membrane  smooth muscle contraction  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting serotonin receptor signaling pathway  chemical synaptic transmission  circadian rhythm  blood circulation  neurotransmitter receptor activity  vasoconstriction  serotonin binding  
Pathways : KEGGRas signaling pathway    Calcium signaling pathway    Neuroactive ligand-receptor interaction    Serotonergic synapse   
NDEx NetworkHTR7
Atlas of Cancer Signalling NetworkHTR7
Wikipedia pathwaysHTR7
Orthology - Evolution
OrthoDB3363
GeneTree (enSembl)ENSG00000148680
Phylogenetic Trees/Animal Genes : TreeFamHTR7
HOVERGENP34969
HOGENOMP34969
Homologs : HomoloGeneHTR7
Homology/Alignments : Family Browser (UCSC)HTR7
Gene fusions - Rearrangements
Tumor Fusion PortalHTR7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHTR7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HTR7
dbVarHTR7
ClinVarHTR7
1000_GenomesHTR7 
Exome Variant ServerHTR7
ExAC (Exome Aggregation Consortium)ENSG00000148680
GNOMAD BrowserENSG00000148680
Genetic variants : HAPMAP3363
Genomic Variants (DGV)HTR7 [DGVbeta]
DECIPHERHTR7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHTR7 
Mutations
ICGC Data PortalHTR7 
TCGA Data PortalHTR7 
Broad Tumor PortalHTR7
OASIS PortalHTR7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHTR7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHTR7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HTR7
DgiDB (Drug Gene Interaction Database)HTR7
DoCM (Curated mutations)HTR7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HTR7 (select a term)
intoGenHTR7
Cancer3DHTR7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182137   
Orphanet
DisGeNETHTR7
MedgenHTR7
Genetic Testing Registry HTR7
NextProtP34969 [Medical]
TSGene3363
GENETestsHTR7
Target ValidationHTR7
Huge Navigator HTR7 [HugePedia]
snp3D : Map Gene to Disease3363
BioCentury BCIQHTR7
ClinGenHTR7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3363
Chemical/Pharm GKB GenePA29561
Clinical trialHTR7
Miscellaneous
canSAR (ICR)HTR7 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHTR7
EVEXHTR7
GoPubMedHTR7
iHOPHTR7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:21:43 CET 2017

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