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HUS1B (HUS1 checkpoint clamp component B)

Identity

Alias_namesHUS1 (S. pombe) checkpoint homolog b
HUS1 checkpoint homolog b (S. pombe)
Other alias-
HGNC (Hugo) HUS1B
LocusID (NCBI) 135458
Atlas_Id 40900
Location 6p25.3  [Link to chromosome band 6p25]
Location_base_pair Starts at 655939 and ends at 656964 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HUS1B   16485
Cards
Entrez_Gene (NCBI)HUS1B  135458  HUS1 checkpoint clamp component B
Aliases
GeneCards (Weizmann)HUS1B
Ensembl hg19 (Hinxton)ENSG00000188996 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188996 [Gene_View]  ENSG00000188996 [Sequence]  chr6:655939-656964 [Contig_View]  HUS1B [Vega]
ICGC DataPortalENSG00000188996
TCGA cBioPortalHUS1B
AceView (NCBI)HUS1B
Genatlas (Paris)HUS1B
WikiGenes135458
SOURCE (Princeton)HUS1B
Genetics Home Reference (NIH)HUS1B
Genomic and cartography
GoldenPath hg38 (UCSC)HUS1B  -     chr6:655939-656964 -  6p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HUS1B  -     6p25.3   [Description]    (hg19-Feb_2009)
EnsemblHUS1B - 6p25.3 [CytoView hg19]  HUS1B - 6p25.3 [CytoView hg38]
Mapping of homologs : NCBIHUS1B [Mapview hg19]  HUS1B [Mapview hg38]
OMIM609713   
Gene and transcription
Genbank (Entrez)AF508547 AI446694 BC101697 BC101699
RefSeq transcript (Entrez)NM_148959
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HUS1B
Cluster EST : UnigeneHs.669039 [ NCBI ]
CGAP (NCI)Hs.669039
Alternative Splicing GalleryENSG00000188996
Gene ExpressionHUS1B [ NCBI-GEO ]   HUS1B [ EBI - ARRAY_EXPRESS ]   HUS1B [ SEEK ]   HUS1B [ MEM ]
Gene Expression Viewer (FireBrowse)HUS1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)135458
GTEX Portal (Tissue expression)HUS1B
Human Protein AtlasENSG00000188996-HUS1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NHY5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NHY5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NHY5
Splice isoforms : SwissVarQ8NHY5
PhosPhoSitePlusQ8NHY5
Domains : Interpro (EBI)Cell_cycle_HUS1    Hus1/Mec3   
Domain families : Pfam (Sanger)Hus1 (PF04005)   
Domain families : Pfam (NCBI)pfam04005   
Conserved Domain (NCBI)HUS1B
DMDM Disease mutations135458
Blocks (Seattle)HUS1B
SuperfamilyQ8NHY5
Human Protein Atlas [tissue]ENSG00000188996-HUS1B [tissue]
Peptide AtlasQ8NHY5
HPRD13722
IPIIPI00169381   
Protein Interaction databases
DIP (DOE-UCLA)Q8NHY5
IntAct (EBI)Q8NHY5
FunCoupENSG00000188996
BioGRIDHUS1B
STRING (EMBL)HUS1B
ZODIACHUS1B
Ontologies - Pathways
QuickGOQ8NHY5
Ontology : AmiGOtelomere maintenance  double-strand break repair via homologous recombination  nucleolus  nucleotide-excision repair  checkpoint clamp complex  intra-S DNA damage checkpoint  mitotic DNA replication checkpoint  site of double-strand break  meiotic DNA integrity checkpoint  
Ontology : EGO-EBItelomere maintenance  double-strand break repair via homologous recombination  nucleolus  nucleotide-excision repair  checkpoint clamp complex  intra-S DNA damage checkpoint  mitotic DNA replication checkpoint  site of double-strand break  meiotic DNA integrity checkpoint  
NDEx NetworkHUS1B
Atlas of Cancer Signalling NetworkHUS1B
Wikipedia pathwaysHUS1B
Orthology - Evolution
OrthoDB135458
GeneTree (enSembl)ENSG00000188996
Phylogenetic Trees/Animal Genes : TreeFamHUS1B
HOVERGENQ8NHY5
HOGENOMQ8NHY5
Homologs : HomoloGeneHUS1B
Homology/Alignments : Family Browser (UCSC)HUS1B
Gene fusions - Rearrangements
Fusion : QuiverHUS1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHUS1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HUS1B
dbVarHUS1B
ClinVarHUS1B
1000_GenomesHUS1B 
Exome Variant ServerHUS1B
ExAC (Exome Aggregation Consortium)ENSG00000188996
GNOMAD BrowserENSG00000188996
Varsome BrowserHUS1B
Genetic variants : HAPMAP135458
Genomic Variants (DGV)HUS1B [DGVbeta]
DECIPHERHUS1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHUS1B 
Mutations
ICGC Data PortalHUS1B 
TCGA Data PortalHUS1B 
Broad Tumor PortalHUS1B
OASIS PortalHUS1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHUS1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHUS1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HUS1B
DgiDB (Drug Gene Interaction Database)HUS1B
DoCM (Curated mutations)HUS1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HUS1B (select a term)
intoGenHUS1B
Cancer3DHUS1B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609713   
Orphanet
DisGeNETHUS1B
MedgenHUS1B
Genetic Testing Registry HUS1B
NextProtQ8NHY5 [Medical]
TSGene135458
GENETestsHUS1B
Target ValidationHUS1B
Huge Navigator HUS1B [HugePedia]
snp3D : Map Gene to Disease135458
BioCentury BCIQHUS1B
ClinGenHUS1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD135458
Chemical/Pharm GKB GenePA134939889
Clinical trialHUS1B
Miscellaneous
canSAR (ICR)HUS1B (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHUS1B
EVEXHUS1B
GoPubMedHUS1B
iHOPHUS1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:12:23 CET 2018

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