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HYAL4 (hyaluronoglucosaminidase 4)

Identity

Other aliasCSHY
HGNC (Hugo) HYAL4
LocusID (NCBI) 23553
Atlas_Id 64478
Location 7q31.32  [Link to chromosome band 7q31]
Location_base_pair Starts at 123845169 and ends at 123877477 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HYAL4   5323
Cards
Entrez_Gene (NCBI)HYAL4  23553  hyaluronoglucosaminidase 4
AliasesCSHY
GeneCards (Weizmann)HYAL4
Ensembl hg19 (Hinxton)ENSG00000106302 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106302 [Gene_View]  chr7:123845169-123877477 [Contig_View]  HYAL4 [Vega]
ICGC DataPortalENSG00000106302
TCGA cBioPortalHYAL4
AceView (NCBI)HYAL4
Genatlas (Paris)HYAL4
WikiGenes23553
SOURCE (Princeton)HYAL4
Genetics Home Reference (NIH)HYAL4
Genomic and cartography
GoldenPath hg38 (UCSC)HYAL4  -     chr7:123845169-123877477 +  7q31.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HYAL4  -     7q31.32   [Description]    (hg19-Feb_2009)
EnsemblHYAL4 - 7q31.32 [CytoView hg19]  HYAL4 - 7q31.32 [CytoView hg38]
Mapping of homologs : NCBIHYAL4 [Mapview hg19]  HYAL4 [Mapview hg38]
OMIM604510   
Gene and transcription
Genbank (Entrez)AB470346 AF009010 BC104788 BC104790 BC143654
RefSeq transcript (Entrez)NM_012269
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HYAL4
Cluster EST : UnigeneHs.28673 [ NCBI ]
CGAP (NCI)Hs.28673
Alternative Splicing GalleryENSG00000106302
Gene ExpressionHYAL4 [ NCBI-GEO ]   HYAL4 [ EBI - ARRAY_EXPRESS ]   HYAL4 [ SEEK ]   HYAL4 [ MEM ]
Gene Expression Viewer (FireBrowse)HYAL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23553
GTEX Portal (Tissue expression)HYAL4
Human Protein AtlasENSG00000106302-HYAL4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2M3T9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2M3T9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2M3T9
Splice isoforms : SwissVarQ2M3T9
Catalytic activity : Enzyme3.2.1.35 [ Enzyme-Expasy ]   3.2.1.353.2.1.35 [ IntEnz-EBI ]   3.2.1.35 [ BRENDA ]   3.2.1.35 [ KEGG ]   
PhosPhoSitePlusQ2M3T9
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)   
Domains : Interpro (EBI)Aldolase_TIM    Glycoside_hydrolase_SF    Hyaluronidase   
Domain families : Pfam (Sanger)Glyco_hydro_56 (PF01630)   
Domain families : Pfam (NCBI)pfam01630   
Conserved Domain (NCBI)HYAL4
DMDM Disease mutations23553
Blocks (Seattle)HYAL4
SuperfamilyQ2M3T9
Human Protein Atlas [tissue]ENSG00000106302-HYAL4 [tissue]
Peptide AtlasQ2M3T9
HPRD05148
IPIIPI00099438   IPI00946616   IPI00946808   IPI00946821   
Protein Interaction databases
DIP (DOE-UCLA)Q2M3T9
IntAct (EBI)Q2M3T9
FunCoupENSG00000106302
BioGRIDHYAL4
STRING (EMBL)HYAL4
ZODIACHYAL4
Ontologies - Pathways
QuickGOQ2M3T9
Ontology : AmiGOhyalurononglucosaminidase activity  carbohydrate metabolic process  glycosaminoglycan catabolic process  cell surface  integral component of membrane  chondroitin sulfate catabolic process  
Ontology : EGO-EBIhyalurononglucosaminidase activity  carbohydrate metabolic process  glycosaminoglycan catabolic process  cell surface  integral component of membrane  chondroitin sulfate catabolic process  
Pathways : KEGGGlycosaminoglycan degradation   
NDEx NetworkHYAL4
Atlas of Cancer Signalling NetworkHYAL4
Wikipedia pathwaysHYAL4
Orthology - Evolution
OrthoDB23553
GeneTree (enSembl)ENSG00000106302
Phylogenetic Trees/Animal Genes : TreeFamHYAL4
HOVERGENQ2M3T9
HOGENOMQ2M3T9
Homologs : HomoloGeneHYAL4
Homology/Alignments : Family Browser (UCSC)HYAL4
Gene fusions - Rearrangements
Tumor Fusion PortalHYAL4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHYAL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HYAL4
dbVarHYAL4
ClinVarHYAL4
1000_GenomesHYAL4 
Exome Variant ServerHYAL4
ExAC (Exome Aggregation Consortium)ENSG00000106302
GNOMAD BrowserENSG00000106302
Genetic variants : HAPMAP23553
Genomic Variants (DGV)HYAL4 [DGVbeta]
DECIPHERHYAL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHYAL4 
Mutations
ICGC Data PortalHYAL4 
TCGA Data PortalHYAL4 
Broad Tumor PortalHYAL4
OASIS PortalHYAL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHYAL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHYAL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HYAL4
DgiDB (Drug Gene Interaction Database)HYAL4
DoCM (Curated mutations)HYAL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HYAL4 (select a term)
intoGenHYAL4
Cancer3DHYAL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604510   
Orphanet
DisGeNETHYAL4
MedgenHYAL4
Genetic Testing Registry HYAL4
NextProtQ2M3T9 [Medical]
TSGene23553
GENETestsHYAL4
Target ValidationHYAL4
Huge Navigator HYAL4 [HugePedia]
snp3D : Map Gene to Disease23553
BioCentury BCIQHYAL4
ClinGenHYAL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23553
Chemical/Pharm GKB GenePA29574
Clinical trialHYAL4
Miscellaneous
canSAR (ICR)HYAL4 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHYAL4
EVEXHYAL4
GoPubMedHYAL4
iHOPHYAL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:16:15 CET 2017

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