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HYI (hydroxypyruvate isomerase (putative))

Identity

Alias_nameshydroxypyruvate isomerase homolog (E. coli)
Alias_symbol (synonym)HT036
HGNC (Hugo) HYI
LocusID (NCBI) 81888
Atlas_Id 42933
Location 1p34.2  [Link to chromosome band 1p34]
Location_base_pair Starts at 43916674 and ends at 43919660 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EIF2B3 (1p34.1) / HYI (1p34.2)HYI (1p34.2) / NFIA (1p31.3)KDM4A (1p34.1) / HYI (1p34.2)
NEDD4L (18q21.31) / HYI (1p34.2)EIF2B3 1p34.1 / HYI 1p34.2HYI 1p34.2 / NFIA 1p31.3
KDM4A 1p34.1 / HYI 1p34.2NEDD4L 18q21.31 / HYI 1p34.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HYI   26948
Cards
Entrez_Gene (NCBI)HYI  81888  hydroxypyruvate isomerase (putative)
AliasesHT036
GeneCards (Weizmann)HYI
Ensembl hg19 (Hinxton)ENSG00000178922 [Gene_View]  chr1:43916674-43919660 [Contig_View]  HYI [Vega]
Ensembl hg38 (Hinxton)ENSG00000178922 [Gene_View]  chr1:43916674-43919660 [Contig_View]  HYI [Vega]
ICGC DataPortalENSG00000178922
TCGA cBioPortalHYI
AceView (NCBI)HYI
Genatlas (Paris)HYI
WikiGenes81888
SOURCE (Princeton)HYI
Genetics Home Reference (NIH)HYI
Genomic and cartography
GoldenPath hg19 (UCSC)HYI  -     chr1:43916674-43919660 -  1p34.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HYI  -     1p34.2   [Description]    (hg38-Dec_2013)
EnsemblHYI - 1p34.2 [CytoView hg19]  HYI - 1p34.2 [CytoView hg38]
Mapping of homologs : NCBIHYI [Mapview hg19]  HYI [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF284750 AF284751 AI023272 AK096244 AY037165
RefSeq transcript (Entrez)NM_001190880 NM_001243526 NM_031207
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_029091 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)HYI
Cluster EST : UnigeneHs.709864 [ NCBI ]
CGAP (NCI)Hs.709864
Alternative Splicing GalleryENSG00000178922
Gene ExpressionHYI [ NCBI-GEO ]   HYI [ EBI - ARRAY_EXPRESS ]   HYI [ SEEK ]   HYI [ MEM ]
Gene Expression Viewer (FireBrowse)HYI [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81888
GTEX Portal (Tissue expression)HYI
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T013   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T013  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T013
Splice isoforms : SwissVarQ5T013
Catalytic activity : Enzyme5.3.1.22 [ Enzyme-Expasy ]   5.3.1.225.3.1.22 [ IntEnz-EBI ]   5.3.1.22 [ BRENDA ]   5.3.1.22 [ KEGG ]   
PhosPhoSitePlusQ5T013
Domains : Interpro (EBI)HyI-like    Xyl_isomerase-like_TIM-brl   
Domain families : Pfam (Sanger)AP_endonuc_2 (PF01261)   
Domain families : Pfam (NCBI)pfam01261   
Conserved Domain (NCBI)HYI
DMDM Disease mutations81888
Blocks (Seattle)HYI
SuperfamilyQ5T013
Human Protein AtlasENSG00000178922
Peptide AtlasQ5T013
HPRD11039
IPIIPI00848045   IPI00847938   IPI00382748   IPI00465271   IPI00514542   IPI00514834   IPI00647220   IPI00982934   IPI00978535   
Protein Interaction databases
DIP (DOE-UCLA)Q5T013
IntAct (EBI)Q5T013
FunCoupENSG00000178922
BioGRIDHYI
STRING (EMBL)HYI
ZODIACHYI
Ontologies - Pathways
QuickGOQ5T013
Ontology : AmiGOmolecular_function  protein binding  cellular_component  biological_process  metabolic process  hydroxypyruvate isomerase activity  
Ontology : EGO-EBImolecular_function  protein binding  cellular_component  biological_process  metabolic process  hydroxypyruvate isomerase activity  
Pathways : KEGGGlyoxylate and dicarboxylate metabolism   
NDEx NetworkHYI
Atlas of Cancer Signalling NetworkHYI
Wikipedia pathwaysHYI
Orthology - Evolution
OrthoDB81888
GeneTree (enSembl)ENSG00000178922
Phylogenetic Trees/Animal Genes : TreeFamHYI
HOVERGENQ5T013
HOGENOMQ5T013
Homologs : HomoloGeneHYI
Homology/Alignments : Family Browser (UCSC)HYI
Gene fusions - Rearrangements
Fusion : MitelmanEIF2B3/HYI [1p34.1/1p34.2]  [t(1;1)(p34;p34)]  
Fusion : MitelmanHYI/NFIA [1p34.2/1p31.3]  [t(1;1)(p31;p34)]  
Fusion : MitelmanKDM4A/HYI [1p34.1/1p34.2]  [t(1;1)(p34;p34)]  
Fusion : MitelmanNEDD4L/HYI [18q21.31/1p34.2]  [t(1;18)(p34;q21)]  
Fusion: TCGAEIF2B3 1p34.1 HYI 1p34.2 BRCA
Fusion: TCGAHYI 1p34.2 NFIA 1p31.3 BRCA
Fusion: TCGAKDM4A 1p34.1 HYI 1p34.2 BRCA
Fusion: TCGANEDD4L 18q21.31 HYI 1p34.2 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHYI [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HYI
dbVarHYI
ClinVarHYI
1000_GenomesHYI 
Exome Variant ServerHYI
ExAC (Exome Aggregation Consortium)HYI (select the gene name)
Genetic variants : HAPMAP81888
Genomic Variants (DGV)HYI [DGVbeta]
DECIPHER (Syndromes)1:43916674-43919660  ENSG00000178922
CONAN: Copy Number AnalysisHYI 
Mutations
ICGC Data PortalHYI 
TCGA Data PortalHYI 
Broad Tumor PortalHYI
OASIS PortalHYI [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHYI  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHYI
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HYI
DgiDB (Drug Gene Interaction Database)HYI
DoCM (Curated mutations)HYI (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HYI (select a term)
intoGenHYI
Cancer3DHYI(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenHYI
Genetic Testing Registry HYI
NextProtQ5T013 [Medical]
TSGene81888
GENETestsHYI
Huge Navigator HYI [HugePedia]
snp3D : Map Gene to Disease81888
BioCentury BCIQHYI
ClinGenHYI
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81888
Chemical/Pharm GKB GenePA142671668
Clinical trialHYI
Miscellaneous
canSAR (ICR)HYI (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHYI
EVEXHYI
GoPubMedHYI
iHOPHYI
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Nov 18 19:39:59 CET 2016

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