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HYOU1 (hypoxia up-regulated 1)

Identity

Alias (NCBI)GRP-170
Grp170
HSP12A
IMD59
ORP-150
ORP150
HGNC (Hugo) HYOU1
HGNC Alias symbORP150
HSP12A
Grp170
HGNC Alias nameglucose-regulated protein 170
LocusID (NCBI) 10525
Atlas_Id 40907
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 119044188 and ends at 119057205 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COLCA2 (11q23.1) / HYOU1 (11q23.3)HMGA1 (6p21.31) / HYOU1 (11q23.3)HYOU1 (11q23.3) / COLCA2 (11q23.1)
HYOU1 (11q23.3) / HMGA1 (6p21.31)HYOU1 (11q23.3) / HYOU1 (11q23.3)HYOU1 (11q23.3) / MTCH1 (6p21.2)
HYOU1 (11q23.3) / PSPH (7p11.2)HYOU1 (11q23.3) / TMEM59 (1p32.3)PEBP4 (8p21.3) / HYOU1 (11q23.3)
RRP15 (1q41) / HYOU1 (11q23.3)TRIM25 (17q22) / HYOU1 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HYOU1   16931
Cards
Entrez_Gene (NCBI)HYOU1    hypoxia up-regulated 1
AliasesGRP-170; Grp170; HSP12A; IMD59; 
ORP-150; ORP150
GeneCards (Weizmann)HYOU1
Ensembl hg19 (Hinxton)ENSG00000149428 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149428 [Gene_View]  ENSG00000149428 [Sequence]  chr11:119044188-119057205 [Contig_View]  HYOU1 [Vega]
ICGC DataPortalENSG00000149428
TCGA cBioPortalHYOU1
AceView (NCBI)HYOU1
Genatlas (Paris)HYOU1
SOURCE (Princeton)HYOU1
Genetics Home Reference (NIH)HYOU1
Genomic and cartography
GoldenPath hg38 (UCSC)HYOU1  -     chr11:119044188-119057205 -  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HYOU1  -     11q23.3   [Description]    (hg19-Feb_2009)
GoldenPathHYOU1 - 11q23.3 [CytoView hg19]  HYOU1 - 11q23.3 [CytoView hg38]
ImmunoBaseENSG00000149428
Genome Data Viewer NCBIHYOU1 [Mapview hg19]  
OMIM233600   601746   
Gene and transcription
Genbank (Entrez)AA580314 AK127324 AK222756 AK294905 AK297260
RefSeq transcript (Entrez)NM_001130991 NM_006389
Consensus coding sequences : CCDS (NCBI)HYOU1
Gene ExpressionHYOU1 [ NCBI-GEO ]   HYOU1 [ EBI - ARRAY_EXPRESS ]   HYOU1 [ SEEK ]   HYOU1 [ MEM ]
Gene Expression Viewer (FireBrowse)HYOU1 [ Firebrowse - Broad ]
GenevisibleExpression of HYOU1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10525
GTEX Portal (Tissue expression)HYOU1
Human Protein AtlasENSG00000149428-HYOU1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4L1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4L1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4L1
PhosPhoSitePlusQ9Y4L1
Domaine pattern : Prosite (Expaxy)HSP70_2 (PS00329)    HSP70_3 (PS01036)   
Domains : Interpro (EBI)ATPase_NBD    Heat_shock_70_CS    HSP70_C_sf    HSP70_peptide-bd_sf    Hsp_70_fam   
Domain families : Pfam (Sanger)HSP70 (PF00012)   
Domain families : Pfam (NCBI)pfam00012   
Conserved Domain (NCBI)HYOU1
SuperfamilyQ9Y4L1
AlphaFold pdb e-kbQ9Y4L1   
Human Protein Atlas [tissue]ENSG00000149428-HYOU1 [tissue]
HPRD03448
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4L1
IntAct (EBI)Q9Y4L1
BioGRIDHYOU1
STRING (EMBL)HYOU1
ZODIACHYOU1
Ontologies - Pathways
QuickGOQ9Y4L1
Ontology : AmiGOresponse to ischemia  protein binding  ATP binding  extracellular region  endoplasmic reticulum  endoplasmic reticulum lumen  smooth endoplasmic reticulum  focal adhesion  endoplasmic reticulum to Golgi vesicle-mediated transport  receptor-mediated endocytosis  membrane  endoplasmic reticulum chaperone complex  response to endoplasmic reticulum stress  IRE1-mediated unfolded protein response  unfolded protein binding  chaperone binding  extracellular exosome  cellular response to hypoxia  cellular response to hypoxia  cellular response to hypoxia  endocytic vesicle lumen  negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway  negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway  negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIresponse to ischemia  protein binding  ATP binding  extracellular region  endoplasmic reticulum  endoplasmic reticulum lumen  smooth endoplasmic reticulum  focal adhesion  endoplasmic reticulum to Golgi vesicle-mediated transport  receptor-mediated endocytosis  membrane  endoplasmic reticulum chaperone complex  response to endoplasmic reticulum stress  IRE1-mediated unfolded protein response  unfolded protein binding  chaperone binding  extracellular exosome  cellular response to hypoxia  cellular response to hypoxia  cellular response to hypoxia  endocytic vesicle lumen  negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway  negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway  negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkHYOU1
Atlas of Cancer Signalling NetworkHYOU1
Wikipedia pathwaysHYOU1
Orthology - Evolution
OrthoDB10525
GeneTree (enSembl)ENSG00000149428
Phylogenetic Trees/Animal Genes : TreeFamHYOU1
Homologs : HomoloGeneHYOU1
Homology/Alignments : Family Browser (UCSC)HYOU1
Gene fusions - Rearrangements
Fusion : MitelmanHYOU1/COLCA2 [11q23.3/11q23.1]  
Fusion : MitelmanHYOU1/HMGA1 [11q23.3/6p21.31]  
Fusion Cancer (Beijing)C11orf93 [HYOU1]  -  11q23.3 [FUSC002681]  [FUSC002681]
Fusion : QuiverHYOU1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHYOU1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HYOU1
dbVarHYOU1
ClinVarHYOU1
MonarchHYOU1
1000_GenomesHYOU1 
Exome Variant ServerHYOU1
GNOMAD BrowserENSG00000149428
Varsome BrowserHYOU1
ACMGHYOU1 variants
VarityQ9Y4L1
Genomic Variants (DGV)HYOU1 [DGVbeta]
DECIPHERHYOU1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHYOU1 
Mutations
ICGC Data PortalHYOU1 
TCGA Data PortalHYOU1 
Broad Tumor PortalHYOU1
OASIS PortalHYOU1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHYOU1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHYOU1
Mutations and Diseases : HGMDHYOU1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHYOU1
DgiDB (Drug Gene Interaction Database)HYOU1
DoCM (Curated mutations)HYOU1
CIViC (Clinical Interpretations of Variants in Cancer)HYOU1
Cancer3DHYOU1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM233600    601746   
Orphanet
DisGeNETHYOU1
MedgenHYOU1
Genetic Testing Registry HYOU1
NextProtQ9Y4L1 [Medical]
GENETestsHYOU1
Target ValidationHYOU1
Huge Navigator HYOU1 [HugePedia]
ClinGenHYOU1
Clinical trials, drugs, therapy
MyCancerGenomeHYOU1
Protein Interactions : CTDHYOU1
Pharm GKB GenePA38427
PharosQ9Y4L1
Clinical trialHYOU1
Miscellaneous
canSAR (ICR)HYOU1
HarmonizomeHYOU1
DataMed IndexHYOU1
Probes
Litterature
PubMed114 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHYOU1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:13:16 CEST 2021

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