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ICA1L (islet cell autoantigen 1 like)

Identity

Alias_namesALS2CR15
ALS2CR14
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 15
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 14
islet cell autoantigen 1,69kDa-like
Other alias
HGNC (Hugo) ICA1L
LocusID (NCBI) 130026
Atlas_Id 64490
Location 2q33.2  [Link to chromosome band 2q33]
Location_base_pair Starts at 202773150 and ends at 202871985 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ICA1L (2q33.2) / HIVEP3 (1p34.2)ICA1L (2q33.2) / NDUFV1 (11q13.2)PTPN23 (3p21.31) / ICA1L (2q33.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ICA1L   14442
Cards
Entrez_Gene (NCBI)ICA1L  130026  islet cell autoantigen 1 like
AliasesALS2CR14; ALS2CR15
GeneCards (Weizmann)ICA1L
Ensembl hg19 (Hinxton)ENSG00000163596 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163596 [Gene_View]  chr2:202773150-202871985 [Contig_View]  ICA1L [Vega]
ICGC DataPortalENSG00000163596
TCGA cBioPortalICA1L
AceView (NCBI)ICA1L
Genatlas (Paris)ICA1L
WikiGenes130026
SOURCE (Princeton)ICA1L
Genetics Home Reference (NIH)ICA1L
Genomic and cartography
GoldenPath hg38 (UCSC)ICA1L  -     chr2:202773150-202871985 -  2q33.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ICA1L  -     2q33.2   [Description]    (hg19-Feb_2009)
EnsemblICA1L - 2q33.2 [CytoView hg19]  ICA1L - 2q33.2 [CytoView hg38]
Mapping of homologs : NCBIICA1L [Mapview hg19]  ICA1L [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB053316 AB053317 AK055978 AK092310 AK124756
RefSeq transcript (Entrez)NM_001288622 NM_001288623 NM_001288624 NM_138468 NM_178231
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ICA1L
Cluster EST : UnigeneHs.516629 [ NCBI ]
CGAP (NCI)Hs.516629
Alternative Splicing GalleryENSG00000163596
Gene ExpressionICA1L [ NCBI-GEO ]   ICA1L [ EBI - ARRAY_EXPRESS ]   ICA1L [ SEEK ]   ICA1L [ MEM ]
Gene Expression Viewer (FireBrowse)ICA1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)130026
GTEX Portal (Tissue expression)ICA1L
Human Protein AtlasENSG00000163596-ICA1L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NDH6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NDH6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NDH6
Splice isoforms : SwissVarQ8NDH6
PhosPhoSitePlusQ8NDH6
Domaine pattern : Prosite (Expaxy)AH (PS50870)   
Domains : Interpro (EBI)AH/BAR-dom    AH_dom    Islet_autoAg_Ica1-like    Islet_autoAg_Ica1/Ica1-like    Islet_autoAg_Ica1_C   
Domain families : Pfam (Sanger)Arfaptin (PF06456)    ICA69 (PF04629)   
Domain families : Pfam (NCBI)pfam06456    pfam04629   
Domain families : Smart (EMBL)Arfaptin (SM01015)  ICA69 (SM01237)  
Conserved Domain (NCBI)ICA1L
DMDM Disease mutations130026
Blocks (Seattle)ICA1L
SuperfamilyQ8NDH6
Human Protein Atlas [tissue]ENSG00000163596-ICA1L [tissue]
Peptide AtlasQ8NDH6
HPRD12446
IPIIPI00179047   IPI00719241   IPI00233358   IPI00926455   IPI00926217   IPI00924985   IPI00925208   IPI00927807   IPI00927155   IPI00926146   IPI00924560   IPI00924823   IPI00925303   IPI00925527   IPI00925963   IPI00926155   
Protein Interaction databases
DIP (DOE-UCLA)Q8NDH6
IntAct (EBI)Q8NDH6
FunCoupENSG00000163596
BioGRIDICA1L
STRING (EMBL)ICA1L
ZODIACICA1L
Ontologies - Pathways
QuickGOQ8NDH6
Ontology : AmiGOacrosomal vesicle  protein binding  spermatid development  protein domain specific binding  
Ontology : EGO-EBIacrosomal vesicle  protein binding  spermatid development  protein domain specific binding  
NDEx NetworkICA1L
Atlas of Cancer Signalling NetworkICA1L
Wikipedia pathwaysICA1L
Orthology - Evolution
OrthoDB130026
GeneTree (enSembl)ENSG00000163596
Phylogenetic Trees/Animal Genes : TreeFamICA1L
HOVERGENQ8NDH6
HOGENOMQ8NDH6
Homologs : HomoloGeneICA1L
Homology/Alignments : Family Browser (UCSC)ICA1L
Gene fusions - Rearrangements
Tumor Fusion PortalICA1L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerICA1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ICA1L
dbVarICA1L
ClinVarICA1L
1000_GenomesICA1L 
Exome Variant ServerICA1L
ExAC (Exome Aggregation Consortium)ENSG00000163596
GNOMAD BrowserENSG00000163596
Genetic variants : HAPMAP130026
Genomic Variants (DGV)ICA1L [DGVbeta]
DECIPHERICA1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisICA1L 
Mutations
ICGC Data PortalICA1L 
TCGA Data PortalICA1L 
Broad Tumor PortalICA1L
OASIS PortalICA1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICICA1L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDICA1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ICA1L
DgiDB (Drug Gene Interaction Database)ICA1L
DoCM (Curated mutations)ICA1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ICA1L (select a term)
intoGenICA1L
Cancer3DICA1L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETICA1L
MedgenICA1L
Genetic Testing Registry ICA1L
NextProtQ8NDH6 [Medical]
TSGene130026
GENETestsICA1L
Target ValidationICA1L
Huge Navigator ICA1L [HugePedia]
snp3D : Map Gene to Disease130026
BioCentury BCIQICA1L
ClinGenICA1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD130026
Chemical/Pharm GKB GenePA24738
Clinical trialICA1L
Miscellaneous
canSAR (ICR)ICA1L (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineICA1L
EVEXICA1L
GoPubMedICA1L
iHOPICA1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:04:43 CET 2017

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