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ICAM2 (intercellular adhesion molecule 2)

Identity

Alias_symbol (synonym)CD102
Other alias
HGNC (Hugo) ICAM2
LocusID (NCBI) 3384
Atlas_Id 40910
Location 17q23.3  [Link to chromosome band 17q23]
Location_base_pair Starts at 64002595 and ends at 64006923 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ICAM2 (17q23.3) / ENO1 (1p36.23)MSI2 (17q22) / ICAM2 (17q23.3)MSI2 17q22 / ICAM2 17q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ICAM2   5345
Cards
Entrez_Gene (NCBI)ICAM2  3384  intercellular adhesion molecule 2
AliasesCD102
GeneCards (Weizmann)ICAM2
Ensembl hg19 (Hinxton)ENSG00000108622 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108622 [Gene_View]  chr17:64002595-64006923 [Contig_View]  ICAM2 [Vega]
ICGC DataPortalENSG00000108622
TCGA cBioPortalICAM2
AceView (NCBI)ICAM2
Genatlas (Paris)ICAM2
WikiGenes3384
SOURCE (Princeton)ICAM2
Genetics Home Reference (NIH)ICAM2
Genomic and cartography
GoldenPath hg38 (UCSC)ICAM2  -     chr17:64002595-64006923 -  17q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ICAM2  -     17q23.3   [Description]    (hg19-Feb_2009)
EnsemblICAM2 - 17q23.3 [CytoView hg19]  ICAM2 - 17q23.3 [CytoView hg38]
Mapping of homologs : NCBIICAM2 [Mapview hg19]  ICAM2 [Mapview hg38]
OMIM146630   
Gene and transcription
Genbank (Entrez)AB209878 AF340052 AF340053 AK223219 AK293110
RefSeq transcript (Entrez)NM_000873 NM_001099786 NM_001099787 NM_001099788 NM_001099789
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ICAM2
Cluster EST : UnigeneHs.431460 [ NCBI ]
CGAP (NCI)Hs.431460
Alternative Splicing GalleryENSG00000108622
Gene ExpressionICAM2 [ NCBI-GEO ]   ICAM2 [ EBI - ARRAY_EXPRESS ]   ICAM2 [ SEEK ]   ICAM2 [ MEM ]
Gene Expression Viewer (FireBrowse)ICAM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3384
GTEX Portal (Tissue expression)ICAM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13598   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP13598  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP13598
Splice isoforms : SwissVarP13598
PhosPhoSitePlusP13598
Domains : Interpro (EBI)ICAM    ICAM2    ICAM_N    ICAM_VCAM_N    Ig-like_dom    Ig-like_fold   
Domain families : Pfam (Sanger)ICAM_N (PF03921)   
Domain families : Pfam (NCBI)pfam03921   
Conserved Domain (NCBI)ICAM2
DMDM Disease mutations3384
Blocks (Seattle)ICAM2
PDB (SRS)1ZXQ   
PDB (PDBSum)1ZXQ   
PDB (IMB)1ZXQ   
PDB (RSDB)1ZXQ   
Structural Biology KnowledgeBase1ZXQ   
SCOP (Structural Classification of Proteins)1ZXQ   
CATH (Classification of proteins structures)1ZXQ   
SuperfamilyP13598
Human Protein AtlasENSG00000108622
Peptide AtlasP13598
HPRD00888
IPIIPI00009477   IPI01017960   
Protein Interaction databases
DIP (DOE-UCLA)P13598
IntAct (EBI)P13598
FunCoupENSG00000108622
BioGRIDICAM2
STRING (EMBL)ICAM2
ZODIACICAM2
Ontologies - Pathways
QuickGOP13598
Ontology : AmiGOuropod  stimulatory C-type lectin receptor signaling pathway  integrin binding  plasma membrane  integral component of plasma membrane  cell adhesion  membrane  single organismal cell-cell adhesion  extracellular matrix organization  cleavage furrow  regulation of immune response  extracellular exosome  
Ontology : EGO-EBIuropod  stimulatory C-type lectin receptor signaling pathway  integrin binding  plasma membrane  integral component of plasma membrane  cell adhesion  membrane  single organismal cell-cell adhesion  extracellular matrix organization  cleavage furrow  regulation of immune response  extracellular exosome  
Pathways : BIOCARTAAdhesion and Diapedesis of Granulocytes [Genes]    Adhesion and Diapedesis of Lymphocytes [Genes]   
Pathways : KEGGCell adhesion molecules (CAMs)    Natural killer cell mediated cytotoxicity   
NDEx NetworkICAM2
Atlas of Cancer Signalling NetworkICAM2
Wikipedia pathwaysICAM2
Orthology - Evolution
OrthoDB3384
GeneTree (enSembl)ENSG00000108622
Phylogenetic Trees/Animal Genes : TreeFamICAM2
HOVERGENP13598
HOGENOMP13598
Homologs : HomoloGeneICAM2
Homology/Alignments : Family Browser (UCSC)ICAM2
Gene fusions - Rearrangements
Fusion : MitelmanMSI2/ICAM2 [17q22/17q23.3]  [t(17;17)(q22;q23)]  
Fusion: TCGAMSI2 17q22 ICAM2 17q23.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerICAM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ICAM2
dbVarICAM2
ClinVarICAM2
1000_GenomesICAM2 
Exome Variant ServerICAM2
ExAC (Exome Aggregation Consortium)ICAM2 (select the gene name)
Genetic variants : HAPMAP3384
Genomic Variants (DGV)ICAM2 [DGVbeta]
DECIPHERICAM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisICAM2 
Mutations
ICGC Data PortalICAM2 
TCGA Data PortalICAM2 
Broad Tumor PortalICAM2
OASIS PortalICAM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICICAM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDICAM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ICAM2
DgiDB (Drug Gene Interaction Database)ICAM2
DoCM (Curated mutations)ICAM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ICAM2 (select a term)
intoGenICAM2
Cancer3DICAM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM146630   
Orphanet
MedgenICAM2
Genetic Testing Registry ICAM2
NextProtP13598 [Medical]
TSGene3384
GENETestsICAM2
Target ValidationICAM2
Huge Navigator ICAM2 [HugePedia]
snp3D : Map Gene to Disease3384
BioCentury BCIQICAM2
ClinGenICAM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3384
Chemical/Pharm GKB GenePA29593
Clinical trialICAM2
Miscellaneous
canSAR (ICR)ICAM2 (select the gene name)
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineICAM2
EVEXICAM2
GoPubMedICAM2
iHOPICAM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:37:49 CEST 2017

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