Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ICAM5 (intercellular adhesion molecule 5)

Identity

Alias (NCBI)TLCN
TLN
HGNC (Hugo) ICAM5
HGNC Alias symbTLN
HGNC Alias nametelencephalin
HGNC Previous nameTLCN
LocusID (NCBI) 7087
Atlas_Id 40912
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 10289952 and ends at 10296778 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ICAM5 (19p13.2) / ANO8 (19p13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ICAM5   5348
Cards
Entrez_Gene (NCBI)ICAM5    intercellular adhesion molecule 5
AliasesTLCN; TLN
GeneCards (Weizmann)ICAM5
Ensembl hg19 (Hinxton)ENSG00000105376 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105376 [Gene_View]  ENSG00000105376 [Sequence]  chr19:10289952-10296778 [Contig_View]  ICAM5 [Vega]
ICGC DataPortalENSG00000105376
TCGA cBioPortalICAM5
AceView (NCBI)ICAM5
Genatlas (Paris)ICAM5
SOURCE (Princeton)ICAM5
Genetics Home Reference (NIH)ICAM5
Genomic and cartography
GoldenPath hg38 (UCSC)ICAM5  -     chr19:10289952-10296778 +  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ICAM5  -     19p13.2   [Description]    (hg19-Feb_2009)
GoldenPathICAM5 - 19p13.2 [CytoView hg19]  ICAM5 - 19p13.2 [CytoView hg38]
ImmunoBaseENSG00000105376
Genome Data Viewer NCBIICAM5 [Mapview hg19]  
OMIM601852   
Gene and transcription
Genbank (Entrez)AI199660 AI568610 AX746344 BC026338 BC030132
RefSeq transcript (Entrez)NM_003259
Consensus coding sequences : CCDS (NCBI)ICAM5
Gene ExpressionICAM5 [ NCBI-GEO ]   ICAM5 [ EBI - ARRAY_EXPRESS ]   ICAM5 [ SEEK ]   ICAM5 [ MEM ]
Gene Expression Viewer (FireBrowse)ICAM5 [ Firebrowse - Broad ]
GenevisibleExpression of ICAM5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7087
GTEX Portal (Tissue expression)ICAM5
Human Protein AtlasENSG00000105376-ICAM5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UMF0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UMF0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UMF0
PhosPhoSitePlusQ9UMF0
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)ICAM    ICAM_N    ICAM_VCAM_N    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_sub2   
Domain families : Pfam (Sanger)ICAM_N (PF03921)    Ig_2 (PF13895)   
Domain families : Pfam (NCBI)pfam03921    pfam13895   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)ICAM5
PDB (RSDB)3BN3    4OI9    4OIA    4OIB   
PDB Europe3BN3    4OI9    4OIA    4OIB   
PDB (PDBSum)3BN3    4OI9    4OIA    4OIB   
PDB (IMB)3BN3    4OI9    4OIA    4OIB   
Structural Biology KnowledgeBase3BN3    4OI9    4OIA    4OIB   
SCOP (Structural Classification of Proteins)3BN3    4OI9    4OIA    4OIB   
CATH (Classification of proteins structures)3BN3    4OI9    4OIA    4OIB   
SuperfamilyQ9UMF0
AlphaFold pdb e-kbQ9UMF0   
Human Protein Atlas [tissue]ENSG00000105376-ICAM5 [tissue]
HPRD03509
Protein Interaction databases
DIP (DOE-UCLA)Q9UMF0
IntAct (EBI)Q9UMF0
BioGRIDICAM5
STRING (EMBL)ICAM5
ZODIACICAM5
Ontologies - Pathways
QuickGOQ9UMF0
Ontology : AmiGOintegrin binding  protein binding  plasma membrane  integral component of plasma membrane  phagocytosis  cell adhesion  extracellular matrix organization  regulation of immune response  cell-cell adhesion  
Ontology : EGO-EBIintegrin binding  protein binding  plasma membrane  integral component of plasma membrane  phagocytosis  cell adhesion  extracellular matrix organization  regulation of immune response  cell-cell adhesion  
NDEx NetworkICAM5
Atlas of Cancer Signalling NetworkICAM5
Wikipedia pathwaysICAM5
Orthology - Evolution
OrthoDB7087
GeneTree (enSembl)ENSG00000105376
Phylogenetic Trees/Animal Genes : TreeFamICAM5
Homologs : HomoloGeneICAM5
Homology/Alignments : Family Browser (UCSC)ICAM5
Gene fusions - Rearrangements
Fusion : QuiverICAM5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerICAM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ICAM5
dbVarICAM5
ClinVarICAM5
MonarchICAM5
1000_GenomesICAM5 
Exome Variant ServerICAM5
GNOMAD BrowserENSG00000105376
Varsome BrowserICAM5
ACMGICAM5 variants
VarityQ9UMF0
Genomic Variants (DGV)ICAM5 [DGVbeta]
DECIPHERICAM5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisICAM5 
Mutations
ICGC Data PortalICAM5 
TCGA Data PortalICAM5 
Broad Tumor PortalICAM5
OASIS PortalICAM5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICICAM5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DICAM5
Mutations and Diseases : HGMDICAM5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaICAM5
DgiDB (Drug Gene Interaction Database)ICAM5
DoCM (Curated mutations)ICAM5
CIViC (Clinical Interpretations of Variants in Cancer)ICAM5
Cancer3DICAM5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601852   
Orphanet
DisGeNETICAM5
MedgenICAM5
Genetic Testing Registry ICAM5
NextProtQ9UMF0 [Medical]
GENETestsICAM5
Target ValidationICAM5
Huge Navigator ICAM5 [HugePedia]
ClinGenICAM5
Clinical trials, drugs, therapy
MyCancerGenomeICAM5
Protein Interactions : CTDICAM5
Pharm GKB GenePA29596
PharosQ9UMF0
Clinical trialICAM5
Miscellaneous
canSAR (ICR)ICAM5
HarmonizomeICAM5
DataMed IndexICAM5
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXICAM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:13:17 CEST 2021

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