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ICT1 (immature colon carcinoma transcript 1)

Identity

Other aliasDS-1
DS1
MRP-L58
HGNC (Hugo) ICT1
LocusID (NCBI) 3396
Atlas_Id 40913
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 73008759 and ends at 73017356 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDR2L (17q25.1) / ICT1 (17q25.1)SAP30BP (17q25.1) / ICT1 (17q25.1)SLC16A5 (17q25.1) / ICT1 (17q25.1)
TMEM94 (17q25.1) / ICT1 (17q25.1)KIAA0195 17q25.1 / ICT1 17q25.1SAP30BP 17q25.1 / ICT1 17q25.1
SLC16A5 17q25.1 / ICT1 17q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ICT1   5359
Cards
Entrez_Gene (NCBI)ICT1  3396  immature colon carcinoma transcript 1
AliasesDS-1; DS1; MRP-L58
GeneCards (Weizmann)ICT1
Ensembl hg19 (Hinxton)ENSG00000167862 [Gene_View]  chr17:73008759-73017356 [Contig_View]  ICT1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000167862 [Gene_View]  chr17:73008759-73017356 [Contig_View]  ICT1 [Vega]
ICGC DataPortalENSG00000167862
TCGA cBioPortalICT1
AceView (NCBI)ICT1
Genatlas (Paris)ICT1
WikiGenes3396
SOURCE (Princeton)ICT1
Genetics Home Reference (NIH)ICT1
Genomic and cartography
GoldenPath hg19 (UCSC)ICT1  -     chr17:73008759-73017356 +  17q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ICT1  -     17q25.1   [Description]    (hg38-Dec_2013)
EnsemblICT1 - 17q25.1 [CytoView hg19]  ICT1 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIICT1 [Mapview hg19]  ICT1 [Mapview hg38]
OMIM603000   
Gene and transcription
Genbank (Entrez)AK222553 AK314138 BC015335 BI870683 BT007111
RefSeq transcript (Entrez)NM_001303265 NM_001545
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)ICT1
Cluster EST : UnigeneHs.407955 [ NCBI ]
CGAP (NCI)Hs.407955
Alternative Splicing GalleryENSG00000167862
Gene ExpressionICT1 [ NCBI-GEO ]   ICT1 [ EBI - ARRAY_EXPRESS ]   ICT1 [ SEEK ]   ICT1 [ MEM ]
Gene Expression Viewer (FireBrowse)ICT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3396
GTEX Portal (Tissue expression)ICT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14197   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14197  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14197
Splice isoforms : SwissVarQ14197
Catalytic activity : Enzyme3.1.1.29 [ Enzyme-Expasy ]   3.1.1.293.1.1.29 [ IntEnz-EBI ]   3.1.1.29 [ BRENDA ]   3.1.1.29 [ KEGG ]   
PhosPhoSitePlusQ14197
Domains : Interpro (EBI)Pep_chain_release_fac_I_II   
Domain families : Pfam (Sanger)RF-1 (PF00472)   
Domain families : Pfam (NCBI)pfam00472   
Conserved Domain (NCBI)ICT1
DMDM Disease mutations3396
Blocks (Seattle)ICT1
PDB (SRS)3J7Y    3J9M   
PDB (PDBSum)3J7Y    3J9M   
PDB (IMB)3J7Y    3J9M   
PDB (RSDB)3J7Y    3J9M   
Structural Biology KnowledgeBase3J7Y    3J9M   
SCOP (Structural Classification of Proteins)3J7Y    3J9M   
CATH (Classification of proteins structures)3J7Y    3J9M   
SuperfamilyQ14197
Human Protein AtlasENSG00000167862
Peptide AtlasQ14197
HPRD04299
IPIIPI00029114   
Protein Interaction databases
DIP (DOE-UCLA)Q14197
IntAct (EBI)Q14197
FunCoupENSG00000167862
BioGRIDICT1
STRING (EMBL)ICT1
ZODIACICT1
Ontologies - Pathways
QuickGOQ14197
Ontology : AmiGOaminoacyl-tRNA hydrolase activity  mitochondrion  mitochondrial inner membrane  mitochondrial matrix  mitochondrial large ribosomal subunit  translation release factor activity, codon specific  translation release factor activity, codon nonspecific  ribosome binding  mitochondrial translational elongation  mitochondrial translational termination  mitochondrial translational termination  rescue of stalled ribosome  
Ontology : EGO-EBIaminoacyl-tRNA hydrolase activity  mitochondrion  mitochondrial inner membrane  mitochondrial matrix  mitochondrial large ribosomal subunit  translation release factor activity, codon specific  translation release factor activity, codon nonspecific  ribosome binding  mitochondrial translational elongation  mitochondrial translational termination  mitochondrial translational termination  rescue of stalled ribosome  
NDEx NetworkICT1
Atlas of Cancer Signalling NetworkICT1
Wikipedia pathwaysICT1
Orthology - Evolution
OrthoDB3396
GeneTree (enSembl)ENSG00000167862
Phylogenetic Trees/Animal Genes : TreeFamICT1
HOVERGENQ14197
HOGENOMQ14197
Homologs : HomoloGeneICT1
Homology/Alignments : Family Browser (UCSC)ICT1
Gene fusions - Rearrangements
Fusion : MitelmanKIAA0195/ICT1 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion : MitelmanSAP30BP/ICT1 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion : MitelmanSLC16A5/ICT1 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion: TCGAKIAA0195 17q25.1 ICT1 17q25.1 BRCA
Fusion: TCGASAP30BP 17q25.1 ICT1 17q25.1 BRCA
Fusion: TCGASLC16A5 17q25.1 ICT1 17q25.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerICT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ICT1
dbVarICT1
ClinVarICT1
1000_GenomesICT1 
Exome Variant ServerICT1
ExAC (Exome Aggregation Consortium)ICT1 (select the gene name)
Genetic variants : HAPMAP3396
Genomic Variants (DGV)ICT1 [DGVbeta]
DECIPHER (Syndromes)17:73008759-73017356  ENSG00000167862
CONAN: Copy Number AnalysisICT1 
Mutations
ICGC Data PortalICT1 
TCGA Data PortalICT1 
Broad Tumor PortalICT1
OASIS PortalICT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICICT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDICT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ICT1
DgiDB (Drug Gene Interaction Database)ICT1
DoCM (Curated mutations)ICT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ICT1 (select a term)
intoGenICT1
Cancer3DICT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603000   
Orphanet
MedgenICT1
Genetic Testing Registry ICT1
NextProtQ14197 [Medical]
TSGene3396
GENETestsICT1
Huge Navigator ICT1 [HugePedia]
snp3D : Map Gene to Disease3396
BioCentury BCIQICT1
ClinGenICT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3396
Chemical/Pharm GKB GenePA29607
Clinical trialICT1
Miscellaneous
canSAR (ICR)ICT1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineICT1
EVEXICT1
GoPubMedICT1
iHOPICT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:04:38 CEST 2017

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