Atlas of Genetics and Cytogenetics in Oncology and Haematology


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IDH3G (isocitrate dehydrogenase 3 (NAD+) gamma)

Identity

Alias_namesisocitrate dehydrogenase 3 (NAD+) gamma
Other aliasH-IDHG
HGNC (Hugo) IDH3G
LocusID (NCBI) 3421
Atlas_Id 64496
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 153051221 and ends at 153059978 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DAZAP1 (19p13.3) / IDH3G (Xq28)IDH3G (Xq28) / PKP2 (12p11.21)IDH3G (Xq28) / UBE2Q2P2 (15q25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IDH3G   5386
Cards
Entrez_Gene (NCBI)IDH3G  3421  isocitrate dehydrogenase 3 (NAD+) gamma
AliasesH-IDHG
GeneCards (Weizmann)IDH3G
Ensembl hg19 (Hinxton)ENSG00000067829 [Gene_View]  chrX:153051221-153059978 [Contig_View]  IDH3G [Vega]
Ensembl hg38 (Hinxton)ENSG00000067829 [Gene_View]  chrX:153051221-153059978 [Contig_View]  IDH3G [Vega]
ICGC DataPortalENSG00000067829
TCGA cBioPortalIDH3G
AceView (NCBI)IDH3G
Genatlas (Paris)IDH3G
WikiGenes3421
SOURCE (Princeton)IDH3G
Genetics Home Reference (NIH)IDH3G
Genomic and cartography
GoldenPath hg19 (UCSC)IDH3G  -     chrX:153051221-153059978 -  Xq28   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)IDH3G  -     Xq28   [Description]    (hg38-Dec_2013)
EnsemblIDH3G - Xq28 [CytoView hg19]  IDH3G - Xq28 [CytoView hg38]
Mapping of homologs : NCBIIDH3G [Mapview hg19]  IDH3G [Mapview hg38]
OMIM300089   
Gene and transcription
Genbank (Entrez)AB209206 AM393133 AM393247 BC000933 BC001902
RefSeq transcript (Entrez)NM_004135 NM_174869
RefSeq genomic (Entrez)NC_000023 NC_018934 NT_011681 NW_004929448
Consensus coding sequences : CCDS (NCBI)IDH3G
Cluster EST : UnigeneHs.410197 [ NCBI ]
CGAP (NCI)Hs.410197
Alternative Splicing GalleryENSG00000067829
Gene ExpressionIDH3G [ NCBI-GEO ]   IDH3G [ EBI - ARRAY_EXPRESS ]   IDH3G [ SEEK ]   IDH3G [ MEM ]
Gene Expression Viewer (FireBrowse)IDH3G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3421
GTEX Portal (Tissue expression)IDH3G
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51553   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51553  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51553
Splice isoforms : SwissVarP51553
Catalytic activity : Enzyme1.1.1.41 [ Enzyme-Expasy ]   1.1.1.411.1.1.41 [ IntEnz-EBI ]   1.1.1.41 [ BRENDA ]   1.1.1.41 [ KEGG ]   
PhosPhoSitePlusP51553
Domaine pattern : Prosite (Expaxy)IDH_IMDH (PS00470)   
Domains : Interpro (EBI)IsoCit/isopropylmalate_DH_CS    Isocitrate/isopropylmalate_DH    Isocitrate_DH_NAD    IsoPropMal-DH-like_dom   
Domain families : Pfam (Sanger)Iso_dh (PF00180)   
Domain families : Pfam (NCBI)pfam00180   
Conserved Domain (NCBI)IDH3G
DMDM Disease mutations3421
Blocks (Seattle)IDH3G
SuperfamilyP51553
Human Protein AtlasENSG00000067829
Peptide AtlasP51553
HPRD02100
IPIIPI00220150   IPI00382584   IPI00844496   IPI00646235   IPI00844297   IPI00335068   IPI00647820   IPI00647368   IPI01011396   
Protein Interaction databases
DIP (DOE-UCLA)P51553
IntAct (EBI)P51553
FunCoupENSG00000067829
BioGRIDIDH3G
STRING (EMBL)IDH3G
ZODIACIDH3G
Ontologies - Pathways
QuickGOP51553
Ontology : AmiGOmagnesium ion binding  isocitrate dehydrogenase (NAD+) activity  ATP binding  nucleoplasm  nucleolus  mitochondrion  mitochondrion  mitochondrial matrix  carbohydrate metabolic process  tricarboxylic acid cycle  isocitrate metabolic process  cellular metabolic process  small molecule metabolic process  NAD binding  
Ontology : EGO-EBImagnesium ion binding  isocitrate dehydrogenase (NAD+) activity  ATP binding  nucleoplasm  nucleolus  mitochondrion  mitochondrion  mitochondrial matrix  carbohydrate metabolic process  tricarboxylic acid cycle  isocitrate metabolic process  cellular metabolic process  small molecule metabolic process  NAD binding  
Pathways : KEGGCitrate cycle (TCA cycle)   
NDEx NetworkIDH3G
Atlas of Cancer Signalling NetworkIDH3G
Wikipedia pathwaysIDH3G
Orthology - Evolution
OrthoDB3421
GeneTree (enSembl)ENSG00000067829
Phylogenetic Trees/Animal Genes : TreeFamIDH3G
HOVERGENP51553
HOGENOMP51553
Homologs : HomoloGeneIDH3G
Homology/Alignments : Family Browser (UCSC)IDH3G
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIDH3G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IDH3G
dbVarIDH3G
ClinVarIDH3G
1000_GenomesIDH3G 
Exome Variant ServerIDH3G
ExAC (Exome Aggregation Consortium)IDH3G (select the gene name)
Genetic variants : HAPMAP3421
Genomic Variants (DGV)IDH3G [DGVbeta]
DECIPHER (Syndromes)X:153051221-153059978  ENSG00000067829
CONAN: Copy Number AnalysisIDH3G 
Mutations
ICGC Data PortalIDH3G 
TCGA Data PortalIDH3G 
Broad Tumor PortalIDH3G
OASIS PortalIDH3G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIDH3G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIDH3G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch IDH3G
DgiDB (Drug Gene Interaction Database)IDH3G
DoCM (Curated mutations)IDH3G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IDH3G (select a term)
intoGenIDH3G
Cancer3DIDH3G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300089   
Orphanet
MedgenIDH3G
Genetic Testing Registry IDH3G
NextProtP51553 [Medical]
TSGene3421
GENETestsIDH3G
Huge Navigator IDH3G [HugePedia]
snp3D : Map Gene to Disease3421
BioCentury BCIQIDH3G
ClinGenIDH3G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3421
Chemical/Pharm GKB GenePA29634
Clinical trialIDH3G
Miscellaneous
canSAR (ICR)IDH3G (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIDH3G
EVEXIDH3G
GoPubMedIDH3G
iHOPIDH3G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:08:28 CET 2017

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