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IDH3G (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma)

Identity

Alias (NCBI)H-IDHG
HGNC (Hugo) IDH3G
HGNC Previous nameisocitrate dehydrogenase 3 (NAD+) gamma
LocusID (NCBI) 3421
Atlas_Id 64496
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 153785768 and ends at 153794375 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DAZAP1 (19p13.3)::IDH3G (Xq28)IDH3G (Xq28)::PKP2 (12p11.21)IDH3G (Xq28)::UBE2Q2P2 (15q25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)IDH3G   5386
Cards
Entrez_Gene (NCBI)IDH3G    isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
AliasesH-IDHG
GeneCards (Weizmann)IDH3G
Ensembl hg19 (Hinxton)ENSG00000067829 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000067829 [Gene_View]  ENSG00000067829 [Sequence]  chrX:153785768-153794375 [Contig_View]  IDH3G [Vega]
ICGC DataPortalENSG00000067829
TCGA cBioPortalIDH3G
AceView (NCBI)IDH3G
Genatlas (Paris)IDH3G
SOURCE (Princeton)IDH3G
Genetics Home Reference (NIH)IDH3G
Genomic and cartography
GoldenPath hg38 (UCSC)IDH3G  -     chrX:153785768-153794375 -  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IDH3G  -     Xq28   [Description]    (hg19-Feb_2009)
GoldenPathIDH3G - Xq28 [CytoView hg19]  IDH3G - Xq28 [CytoView hg38]
ImmunoBaseENSG00000067829
Genome Data Viewer NCBIIDH3G [Mapview hg19]  
OMIM300089   
Gene and transcription
Genbank (Entrez)AB209206 BC000933 BC001902 BI831096 U40272
RefSeq transcript (Entrez)NM_004135 NM_174869
Consensus coding sequences : CCDS (NCBI)IDH3G
Gene ExpressionIDH3G [ NCBI-GEO ]   IDH3G [ EBI - ARRAY_EXPRESS ]   IDH3G [ SEEK ]   IDH3G [ MEM ]
Gene Expression Viewer (FireBrowse)IDH3G [ Firebrowse - Broad ]
GenevisibleExpression of IDH3G in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3421
GTEX Portal (Tissue expression)IDH3G
Human Protein AtlasENSG00000067829-IDH3G [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51553   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51553  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51553
PhosPhoSitePlusP51553
Domaine pattern : Prosite (Expaxy)IDH_IMDH (PS00470)   
Domains : Interpro (EBI)IsoCit/isopropylmalate_DH_CS    Isocitrate_DH_NAD    IsoPropMal-DH-like_dom   
Domain families : Pfam (Sanger)Iso_dh (PF00180)   
Domain families : Pfam (NCBI)pfam00180   
Domain families : Smart (EMBL)Iso_dh (SM01329)  
Conserved Domain (NCBI)IDH3G
PDB (RSDB)5GRE    5GRF    5GRH    5GRI    5GRL    5YVT    6L57    6L59   
PDB Europe5GRE    5GRF    5GRH    5GRI    5GRL    5YVT    6L57    6L59   
PDB (PDBSum)5GRE    5GRF    5GRH    5GRI    5GRL    5YVT    6L57    6L59   
PDB (IMB)5GRE    5GRF    5GRH    5GRI    5GRL    5YVT    6L57    6L59   
Structural Biology KnowledgeBase5GRE    5GRF    5GRH    5GRI    5GRL    5YVT    6L57    6L59   
SCOP (Structural Classification of Proteins)5GRE    5GRF    5GRH    5GRI    5GRL    5YVT    6L57    6L59   
CATH (Classification of proteins structures)5GRE    5GRF    5GRH    5GRI    5GRL    5YVT    6L57    6L59   
SuperfamilyP51553
AlphaFold pdb e-kbP51553   
Human Protein Atlas [tissue]ENSG00000067829-IDH3G [tissue]
HPRD02100
Protein Interaction databases
DIP (DOE-UCLA)P51553
IntAct (EBI)P51553
BioGRIDIDH3G
STRING (EMBL)IDH3G
ZODIACIDH3G
Ontologies - Pathways
QuickGOP51553
Ontology : AmiGOmagnesium ion binding  isocitrate dehydrogenase (NAD+) activity  isocitrate dehydrogenase (NAD+) activity  protein binding  ATP binding  nucleolus  mitochondrion  mitochondrion  mitochondrion  mitochondrial matrix  carbohydrate metabolic process  tricarboxylic acid cycle  tricarboxylic acid cycle  isocitrate metabolic process  isocitrate metabolic process  NAD binding  
Ontology : EGO-EBImagnesium ion binding  isocitrate dehydrogenase (NAD+) activity  isocitrate dehydrogenase (NAD+) activity  protein binding  ATP binding  nucleolus  mitochondrion  mitochondrion  mitochondrion  mitochondrial matrix  carbohydrate metabolic process  tricarboxylic acid cycle  tricarboxylic acid cycle  isocitrate metabolic process  isocitrate metabolic process  NAD binding  
Pathways : KEGGCitrate cycle (TCA cycle)   
NDEx NetworkIDH3G
Atlas of Cancer Signalling NetworkIDH3G
Wikipedia pathwaysIDH3G
Orthology - Evolution
OrthoDB3421
GeneTree (enSembl)ENSG00000067829
Phylogenetic Trees/Animal Genes : TreeFamIDH3G
Homologs : HomoloGeneIDH3G
Homology/Alignments : Family Browser (UCSC)IDH3G
Gene fusions - Rearrangements
Fusion : QuiverIDH3G
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIDH3G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IDH3G
dbVarIDH3G
ClinVarIDH3G
MonarchIDH3G
1000_GenomesIDH3G 
Exome Variant ServerIDH3G
GNOMAD BrowserENSG00000067829
Varsome BrowserIDH3G
ACMGIDH3G variants
VarityP51553
Genomic Variants (DGV)IDH3G [DGVbeta]
DECIPHERIDH3G [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIDH3G 
Mutations
ICGC Data PortalIDH3G 
TCGA Data PortalIDH3G 
Broad Tumor PortalIDH3G
OASIS PortalIDH3G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIDH3G  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIDH3G
Mutations and Diseases : HGMDIDH3G
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaIDH3G
DgiDB (Drug Gene Interaction Database)IDH3G
DoCM (Curated mutations)IDH3G
CIViC (Clinical Interpretations of Variants in Cancer)IDH3G
Cancer3DIDH3G
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300089   
Orphanet
DisGeNETIDH3G
MedgenIDH3G
Genetic Testing Registry IDH3G
NextProtP51553 [Medical]
GENETestsIDH3G
Target ValidationIDH3G
Huge Navigator IDH3G [HugePedia]
ClinGenIDH3G
Clinical trials, drugs, therapy
MyCancerGenomeIDH3G
Protein Interactions : CTDIDH3G
Pharm GKB GenePA29634
PharosP51553
Clinical trialIDH3G
Miscellaneous
canSAR (ICR)IDH3G
HarmonizomeIDH3G
ARCHS4IDH3G
DataMed IndexIDH3G
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIDH3G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 18:56:16 CET 2022

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