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IDS (iduronate 2-sulfatase)

Identity

Alias_namesSIDS
Other aliasMPS2
HGNC (Hugo) IDS
LocusID (NCBI) 3423
Atlas_Id 56288
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 149476990 and ends at 149505354 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AFMID (17q25.3) / IDS (Xq28)IDS (Xq28) / AFMID (17q25.3)IDS (Xq28) / CXorf40B (Xq28)
IDS (Xq28) / IDS (Xq28)IDS (Xq28) / LOC100131434 ()IDS (Xq28) / PAIP2 (5q31.2)
IDS (Xq28) / PUM2 (2p24.1)IDS (Xq28) / SNHG3 (1p35.3)LOC100131434 () / IDS (Xq28)
PGAM5 (12q24.33) / IDS (Xq28)PPM1K (4q22.1) / IDS (Xq28)TAOK1 (17q11.2) / IDS (Xq28)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IDS   5389
Cards
Entrez_Gene (NCBI)IDS  3423  iduronate 2-sulfatase
AliasesMPS2; SIDS
GeneCards (Weizmann)IDS
Ensembl hg19 (Hinxton)ENSG00000010404 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000010404 [Gene_View]  chrX:149476990-149505354 [Contig_View]  IDS [Vega]
ICGC DataPortalENSG00000010404
TCGA cBioPortalIDS
AceView (NCBI)IDS
Genatlas (Paris)IDS
WikiGenes3423
SOURCE (Princeton)IDS
Genetics Home Reference (NIH)IDS
Genomic and cartography
GoldenPath hg38 (UCSC)IDS  -     chrX:149476990-149505354 -  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IDS  -     Xq28   [Description]    (hg19-Feb_2009)
EnsemblIDS - Xq28 [CytoView hg19]  IDS - Xq28 [CytoView hg38]
Mapping of homologs : NCBIIDS [Mapview hg19]  IDS [Mapview hg38]
OMIM300823   309900   
Gene and transcription
Genbank (Entrez)AF050145 AI242974 AK055600 AK057191 AK294541
RefSeq transcript (Entrez)NM_000202 NM_001166550 NM_006123
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IDS
Cluster EST : UnigeneHs.460960 [ NCBI ]
CGAP (NCI)Hs.460960
Alternative Splicing GalleryENSG00000010404
Gene ExpressionIDS [ NCBI-GEO ]   IDS [ EBI - ARRAY_EXPRESS ]   IDS [ SEEK ]   IDS [ MEM ]
Gene Expression Viewer (FireBrowse)IDS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3423
GTEX Portal (Tissue expression)IDS
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22304   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22304  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22304
Splice isoforms : SwissVarP22304
Catalytic activity : Enzyme3.1.6.13 [ Enzyme-Expasy ]   3.1.6.133.1.6.13 [ IntEnz-EBI ]   3.1.6.13 [ BRENDA ]   3.1.6.13 [ KEGG ]   
PhosPhoSitePlusP22304
Domaine pattern : Prosite (Expaxy)SULFATASE_1 (PS00523)    SULFATASE_2 (PS00149)   
Domains : Interpro (EBI)Alkaline_Pase-like_a/b/a    Alkaline_phosphatase_core    Sulfatase_CS    Sulfatase_N   
Domain families : Pfam (Sanger)Sulfatase (PF00884)   
Domain families : Pfam (NCBI)pfam00884   
Conserved Domain (NCBI)IDS
DMDM Disease mutations3423
Blocks (Seattle)IDS
PDB (SRS)5FQL   
PDB (PDBSum)5FQL   
PDB (IMB)5FQL   
PDB (RSDB)5FQL   
Structural Biology KnowledgeBase5FQL   
SCOP (Structural Classification of Proteins)5FQL   
CATH (Classification of proteins structures)5FQL   
SuperfamilyP22304
Human Protein AtlasENSG00000010404
Peptide AtlasP22304
HPRD02402
IPIIPI00026104   IPI00006121   IPI00013771   IPI01013661   IPI00953993   IPI00640469   IPI00976651   IPI00980298   
Protein Interaction databases
DIP (DOE-UCLA)P22304
IntAct (EBI)P22304
FunCoupENSG00000010404
BioGRIDIDS
STRING (EMBL)IDS
ZODIACIDS
Ontologies - Pathways
QuickGOP22304
Ontology : AmiGOiduronate-2-sulfatase activity  glycosaminoglycan catabolic process  chondroitin sulfate catabolic process  lysosomal lumen  metal ion binding  
Ontology : EGO-EBIiduronate-2-sulfatase activity  glycosaminoglycan catabolic process  chondroitin sulfate catabolic process  lysosomal lumen  metal ion binding  
Pathways : KEGGGlycosaminoglycan degradation    Lysosome   
NDEx NetworkIDS
Atlas of Cancer Signalling NetworkIDS
Wikipedia pathwaysIDS
Orthology - Evolution
OrthoDB3423
GeneTree (enSembl)ENSG00000010404
Phylogenetic Trees/Animal Genes : TreeFamIDS
HOVERGENP22304
HOGENOMP22304
Homologs : HomoloGeneIDS
Homology/Alignments : Family Browser (UCSC)IDS
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIDS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IDS
dbVarIDS
ClinVarIDS
1000_GenomesIDS 
Exome Variant ServerIDS
ExAC (Exome Aggregation Consortium)IDS (select the gene name)
Genetic variants : HAPMAP3423
Genomic Variants (DGV)IDS [DGVbeta]
DECIPHERIDS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIDS 
Mutations
ICGC Data PortalIDS 
TCGA Data PortalIDS 
Broad Tumor PortalIDS
OASIS PortalIDS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIDS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIDS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch IDS
DgiDB (Drug Gene Interaction Database)IDS
DoCM (Curated mutations)IDS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IDS (select a term)
intoGenIDS
Cancer3DIDS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300823    309900   
Orphanet18825    18824   
MedgenIDS
Genetic Testing Registry IDS
NextProtP22304 [Medical]
TSGene3423
GENETestsIDS
Target ValidationIDS
Huge Navigator IDS [HugePedia]
snp3D : Map Gene to Disease3423
BioCentury BCIQIDS
ClinGenIDS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3423
Chemical/Pharm GKB GenePA29636
Clinical trialIDS
Miscellaneous
canSAR (ICR)IDS (select the gene name)
Probes
Litterature
PubMed95 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIDS
EVEXIDS
GoPubMedIDS
iHOPIDS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:12:41 CEST 2017

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