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IFI27 (interferon alpha inducible protein 27)

Identity

Alias_symbol (synonym)P27
FAM14D
ISG12
Other aliasISG12A
HGNC (Hugo) IFI27
LocusID (NCBI) 3429
Atlas_Id 46294
Location 14q32.12  [Link to chromosome band 14q32]
Location_base_pair Starts at 94110733 and ends at 94116699 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IFI27 (14q32.12) / CPNE3 (8q21.3)IFI27 (14q32.12) / GAD1 (2q31.1)IFI27 (14q32.12) / IFI27 (14q32.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFI27   5397
Cards
Entrez_Gene (NCBI)IFI27  3429  interferon alpha inducible protein 27
AliasesFAM14D; ISG12; ISG12A; P27
GeneCards (Weizmann)IFI27
Ensembl hg19 (Hinxton)ENSG00000165949 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165949 [Gene_View]  chr14:94110733-94116699 [Contig_View]  IFI27 [Vega]
ICGC DataPortalENSG00000165949
TCGA cBioPortalIFI27
AceView (NCBI)IFI27
Genatlas (Paris)IFI27
WikiGenes3429
SOURCE (Princeton)IFI27
Genetics Home Reference (NIH)IFI27
Genomic and cartography
GoldenPath hg38 (UCSC)IFI27  -     chr14:94110733-94116699 +  14q32.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFI27  -     14q32.12   [Description]    (hg19-Feb_2009)
EnsemblIFI27 - 14q32.12 [CytoView hg19]  IFI27 - 14q32.12 [CytoView hg38]
Mapping of homologs : NCBIIFI27 [Mapview hg19]  IFI27 [Mapview hg38]
OMIM600009   
Gene and transcription
Genbank (Entrez)AI799552 AJ294851 AK095039 AK097084 AK289535
RefSeq transcript (Entrez)NM_001130080 NM_001288952 NM_001288954 NM_001288956 NM_001288957 NM_001288958 NM_001288959 NM_001288960 NM_001288995 NM_005532
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_187601
Consensus coding sequences : CCDS (NCBI)IFI27
Cluster EST : UnigeneHs.532634 [ NCBI ]
CGAP (NCI)Hs.532634
Alternative Splicing GalleryENSG00000165949
Gene ExpressionIFI27 [ NCBI-GEO ]   IFI27 [ EBI - ARRAY_EXPRESS ]   IFI27 [ SEEK ]   IFI27 [ MEM ]
Gene Expression Viewer (FireBrowse)IFI27 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3429
GTEX Portal (Tissue expression)IFI27
Protein : pattern, domain, 3D structure
UniProt/SwissProtP40305   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP40305  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP40305
Splice isoforms : SwissVarP40305
PhosPhoSitePlusP40305
Domains : Interpro (EBI)IFI6/IFI27   
Domain families : Pfam (Sanger)Ifi-6-16 (PF06140)   
Domain families : Pfam (NCBI)pfam06140   
Conserved Domain (NCBI)IFI27
DMDM Disease mutations3429
Blocks (Seattle)IFI27
SuperfamilyP40305
Human Protein AtlasENSG00000165949
Peptide AtlasP40305
HPRD02479
IPIIPI00793404   IPI00943312   IPI00940826   IPI01024852   IPI01026009   IPI01026114   IPI01024709   IPI01026363   IPI01026494   IPI01025229   IPI01025350   IPI00910748   
Protein Interaction databases
DIP (DOE-UCLA)P40305
IntAct (EBI)P40305
FunCoupENSG00000165949
BioGRIDIFI27
STRING (EMBL)IFI27
ZODIACIFI27
Ontologies - Pathways
QuickGOP40305
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II activating transcription factor binding  molecular_function  lamin binding  nuclear inner membrane  mitochondrion  mitochondrial outer membrane  activation of cysteine-type endopeptidase activity involved in apoptotic process  integral component of membrane  regulation of protein export from nucleus  type I interferon signaling pathway  apoptotic signaling pathway  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II activating transcription factor binding  molecular_function  lamin binding  nuclear inner membrane  mitochondrion  mitochondrial outer membrane  activation of cysteine-type endopeptidase activity involved in apoptotic process  integral component of membrane  regulation of protein export from nucleus  type I interferon signaling pathway  apoptotic signaling pathway  
NDEx NetworkIFI27
Atlas of Cancer Signalling NetworkIFI27
Wikipedia pathwaysIFI27
Orthology - Evolution
OrthoDB3429
GeneTree (enSembl)ENSG00000165949
Phylogenetic Trees/Animal Genes : TreeFamIFI27
HOVERGENP40305
HOGENOMP40305
Homologs : HomoloGeneIFI27
Homology/Alignments : Family Browser (UCSC)IFI27
Gene fusions - Rearrangements
Fusion : MitelmanIFI27/CPNE3 [14q32.12/8q21.3]  
Fusion Cancer (Beijing)IFI27 [14q32.12]  -  GAD1 [2q31.1]  [FUSC002861]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFI27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFI27
dbVarIFI27
ClinVarIFI27
1000_GenomesIFI27 
Exome Variant ServerIFI27
ExAC (Exome Aggregation Consortium)IFI27 (select the gene name)
Genetic variants : HAPMAP3429
Genomic Variants (DGV)IFI27 [DGVbeta]
DECIPHERIFI27 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFI27 
Mutations
ICGC Data PortalIFI27 
TCGA Data PortalIFI27 
Broad Tumor PortalIFI27
OASIS PortalIFI27 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDIFI27
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFI27
DgiDB (Drug Gene Interaction Database)IFI27
DoCM (Curated mutations)IFI27 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFI27 (select a term)
intoGenIFI27
Cancer3DIFI27(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600009   
Orphanet
MedgenIFI27
Genetic Testing Registry IFI27
NextProtP40305 [Medical]
TSGene3429
GENETestsIFI27
Target ValidationIFI27
Huge Navigator IFI27 [HugePedia]
snp3D : Map Gene to Disease3429
BioCentury BCIQIFI27
ClinGenIFI27
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3429
Chemical/Pharm GKB GenePA29643
Clinical trialIFI27
Miscellaneous
canSAR (ICR)IFI27 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFI27
EVEXIFI27
GoPubMedIFI27
iHOPIFI27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:56:00 CEST 2017

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