Atlas of Genetics and Cytogenetics in Oncology and Haematology

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IFI30 (IFI30 lysosomal thiol reductase)

Identity

Alias_namesinterferon gamma inducible protein 30
IFI30, lysosomal thiol reductase
Alias_symbol (synonym)IFI-30
GILT
IP30
MGC32056
IP-30
Other alias
HGNC (Hugo) IFI30
LocusID (NCBI) 10437
Atlas_Id 43910
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 18173780 and ends at 18178124 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IFI30   5398
Cards
Entrez_Gene (NCBI)IFI30  10437  IFI30 lysosomal thiol reductase
AliasesGILT; IFI-30; IP-30; IP30
GeneCards (Weizmann)IFI30
Ensembl hg19 (Hinxton)ENSG00000216490 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000216490 [Gene_View]  ENSG00000216490 [Sequence]  chr19:18173780-18178124 [Contig_View]  IFI30 [Vega]
ICGC DataPortalENSG00000216490
TCGA cBioPortalIFI30
AceView (NCBI)IFI30
Genatlas (Paris)IFI30
WikiGenes10437
SOURCE (Princeton)IFI30
Genetics Home Reference (NIH)IFI30
Genomic and cartography
GoldenPath hg38 (UCSC)IFI30  -     chr19:18173780-18178124 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFI30  -     19p13.11   [Description]    (hg19-Feb_2009)
GoldenPathIFI30 - 19p13.11 [CytoView hg19]  IFI30 - 19p13.11 [CytoView hg38]
ImmunoBaseENSG00000216490
Mapping of homologs : NCBIIFI30 [Mapview hg19]  IFI30 [Mapview hg38]
OMIM604664   
Gene and transcription
Genbank (Entrez)AB049659 AF097362 AF401212 AI022513 AK123477
RefSeq transcript (Entrez)NM_006332
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFI30
Cluster EST : UnigeneHs.14623 [ NCBI ]
CGAP (NCI)Hs.14623
Alternative Splicing GalleryENSG00000216490
Gene ExpressionIFI30 [ NCBI-GEO ]   IFI30 [ EBI - ARRAY_EXPRESS ]   IFI30 [ SEEK ]   IFI30 [ MEM ]
Gene Expression Viewer (FireBrowse)IFI30 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10437
GTEX Portal (Tissue expression)IFI30
Human Protein AtlasENSG00000216490-IFI30 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13284   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP13284  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP13284
Splice isoforms : SwissVarP13284
PhosPhoSitePlusP13284
Domains : Interpro (EBI)Interferon-induced_GILT   
Domain families : Pfam (Sanger)GILT (PF03227)   
Domain families : Pfam (NCBI)pfam03227   
Conserved Domain (NCBI)IFI30
DMDM Disease mutations10437
Blocks (Seattle)IFI30
SuperfamilyP13284
Human Protein Atlas [tissue]ENSG00000216490-IFI30 [tissue]
Peptide AtlasP13284
HPRD05234
IPIIPI00007853   IPI00816038   IPI00871537   
Protein Interaction databases
DIP (DOE-UCLA)P13284
IntAct (EBI)P13284
FunCoupENSG00000216490
BioGRIDIFI30
STRING (EMBL)IFI30
ZODIACIFI30
Ontologies - Pathways
QuickGOP13284
Ontology : AmiGOprotein binding  extracellular region  lysosome  cytosol  oxidoreductase activity, acting on a sulfur group of donors  oxidoreductase activity, acting on a sulfur group of donors  antigen processing and presentation of exogenous peptide antigen via MHC class II  cell junction  antigen processing and presentation of exogenous peptide antigen via MHC class I  lysosomal lumen  intracellular membrane-bounded organelle  oxidation-reduction process  interferon-gamma-mediated signaling pathway  
Ontology : EGO-EBIprotein binding  extracellular region  lysosome  cytosol  oxidoreductase activity, acting on a sulfur group of donors  oxidoreductase activity, acting on a sulfur group of donors  antigen processing and presentation of exogenous peptide antigen via MHC class II  cell junction  antigen processing and presentation of exogenous peptide antigen via MHC class I  lysosomal lumen  intracellular membrane-bounded organelle  oxidation-reduction process  interferon-gamma-mediated signaling pathway  
Pathways : KEGGAntigen processing and presentation   
NDEx NetworkIFI30
Atlas of Cancer Signalling NetworkIFI30
Wikipedia pathwaysIFI30
Orthology - Evolution
OrthoDB10437
GeneTree (enSembl)ENSG00000216490
Phylogenetic Trees/Animal Genes : TreeFamIFI30
HOGENOMP13284
Homologs : HomoloGeneIFI30
Homology/Alignments : Family Browser (UCSC)IFI30
Gene fusions - Rearrangements
Fusion : QuiverIFI30
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFI30 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFI30
dbVarIFI30
ClinVarIFI30
1000_GenomesIFI30 
Exome Variant ServerIFI30
ExAC (Exome Aggregation Consortium)ENSG00000216490
GNOMAD BrowserENSG00000216490
Varsome BrowserIFI30
Genetic variants : HAPMAP10437
Genomic Variants (DGV)IFI30 [DGVbeta]
DECIPHERIFI30 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFI30 
Mutations
ICGC Data PortalIFI30 
TCGA Data PortalIFI30 
Broad Tumor PortalIFI30
OASIS PortalIFI30 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFI30  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIFI30
Mutations and Diseases : HGMDIFI30
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFI30
DgiDB (Drug Gene Interaction Database)IFI30
DoCM (Curated mutations)IFI30 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFI30 (select a term)
intoGenIFI30
Cancer3DIFI30(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604664   
Orphanet
DisGeNETIFI30
MedgenIFI30
Genetic Testing Registry IFI30
NextProtP13284 [Medical]
TSGene10437
GENETestsIFI30
Target ValidationIFI30
Huge Navigator IFI30 [HugePedia]
snp3D : Map Gene to Disease10437
BioCentury BCIQIFI30
ClinGenIFI30
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10437
Chemical/Pharm GKB GenePA29644
Clinical trialIFI30
Miscellaneous
canSAR (ICR)IFI30 (select the gene name)
DataMed IndexIFI30
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFI30
EVEXIFI30
GoPubMedIFI30
iHOPIFI30
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:47:46 CET 2019
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