IFI44 (interferon induced protein 44)

2014-11-01  

Identity

HGNC
LOCATION
1p31.1
LOCUSID
ALIAS
MTAP44,TLDC5,p44

Other Information

Locus ID:

NCBI: 10561
MIM: 610468
HGNC: 16938
Ensembl: ENSG00000137965

Variants:

dbSNP: 10561
ClinVar: 10561
TCGA: ENSG00000137965
COSMIC: IFI44

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137965ENST00000370747Q8TCB0
ENSG00000137965ENST00000438486C9JUM8
ENSG00000137965ENST00000446486H7C1F3

Expression (GTEx)

0
50
100
150
200
250

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
177848192007Antiproliferative activity of the human IFN-alpha-inducible protein IFI44.33
257767612015IFI44 suppresses HIV-1 LTR promoter activity and facilitates its latency.28
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
228966022012Viperin, MTAP44, and protein kinase R contribute to the interferon-induced inhibition of Bunyamwera Orthobunyavirus replication.26
168868952006Genetic predisposition of responsiveness to therapy for chronic hepatitis C.12
314556512019Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication.4
189534822008Polymorphisms of interferons and their receptors in the genetics of severe RSV-associated diseases.2

Citation

Dessen P

IFI44 (interferon induced protein 44)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64507/ifi44