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IFIT2 (interferon induced protein with tetratricopeptide repeats 2)

Identity

Alias_namesIFI54
G10P2
interferon-induced protein with tetratricopeptide repeats 2
Alias_symbol (synonym)IFI-54
ISG-54K
cig42
GARG-39
Other aliasIFI-54K
IFIT-2
ISG-54 K
ISG54
P54
HGNC (Hugo) IFIT2
LocusID (NCBI) 3433
Atlas_Id 47644
Location 10q23.31  [Link to chromosome band 10q23]
Location_base_pair Starts at 89301949 and ends at 89309276 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFIT2   5409
Cards
Entrez_Gene (NCBI)IFIT2  3433  interferon induced protein with tetratricopeptide repeats 2
AliasesG10P2; GARG-39; IFI-54; IFI-54K; 
IFI54; IFIT-2; ISG-54; ISG-54K; ISG54; P54; cig42
GeneCards (Weizmann)IFIT2
Ensembl hg19 (Hinxton)ENSG00000119922 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119922 [Gene_View]  chr10:89301949-89309276 [Contig_View]  IFIT2 [Vega]
ICGC DataPortalENSG00000119922
TCGA cBioPortalIFIT2
AceView (NCBI)IFIT2
Genatlas (Paris)IFIT2
WikiGenes3433
SOURCE (Princeton)IFIT2
Genetics Home Reference (NIH)IFIT2
Genomic and cartography
GoldenPath hg38 (UCSC)IFIT2  -     chr10:89301949-89309276 +  10q23.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFIT2  -     10q23.31   [Description]    (hg19-Feb_2009)
EnsemblIFIT2 - 10q23.31 [CytoView hg19]  IFIT2 - 10q23.31 [CytoView hg38]
Mapping of homologs : NCBIIFIT2 [Mapview hg19]  IFIT2 [Mapview hg38]
OMIM147040   
Gene and transcription
Genbank (Entrez)AA143609 AA765174 AF026944 AK300431 AK312831
RefSeq transcript (Entrez)NM_001547
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFIT2
Cluster EST : UnigeneHs.437609 [ NCBI ]
CGAP (NCI)Hs.437609
Alternative Splicing GalleryENSG00000119922
Gene ExpressionIFIT2 [ NCBI-GEO ]   IFIT2 [ EBI - ARRAY_EXPRESS ]   IFIT2 [ SEEK ]   IFIT2 [ MEM ]
Gene Expression Viewer (FireBrowse)IFIT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3433
GTEX Portal (Tissue expression)IFIT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09913   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09913  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09913
Splice isoforms : SwissVarP09913
PhosPhoSitePlusP09913
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)Interferon-induced_IFIT2    TPR-contain_dom    TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)IFIT2
DMDM Disease mutations3433
Blocks (Seattle)IFIT2
PDB (SRS)4G1T   
PDB (PDBSum)4G1T   
PDB (IMB)4G1T   
PDB (RSDB)4G1T   
Structural Biology KnowledgeBase4G1T   
SCOP (Structural Classification of Proteins)4G1T   
CATH (Classification of proteins structures)4G1T   
SuperfamilyP09913
Human Protein AtlasENSG00000119922
Peptide AtlasP09913
HPRD00913
IPIIPI00018298   
Protein Interaction databases
DIP (DOE-UCLA)P09913
IntAct (EBI)P09913
FunCoupENSG00000119922
BioGRIDIFIT2
STRING (EMBL)IFIT2
ZODIACIFIT2
Ontologies - Pathways
QuickGOP09913
Ontology : AmiGORNA binding  protein binding  cytoplasm  endoplasmic reticulum  cytosol  apoptotic mitochondrial changes  response to virus  response to virus  negative regulation of protein binding  cellular response to interferon-alpha  positive regulation of apoptotic process  defense response to virus  type I interferon signaling pathway  
Ontology : EGO-EBIRNA binding  protein binding  cytoplasm  endoplasmic reticulum  cytosol  apoptotic mitochondrial changes  response to virus  response to virus  negative regulation of protein binding  cellular response to interferon-alpha  positive regulation of apoptotic process  defense response to virus  type I interferon signaling pathway  
NDEx NetworkIFIT2
Atlas of Cancer Signalling NetworkIFIT2
Wikipedia pathwaysIFIT2
Orthology - Evolution
OrthoDB3433
GeneTree (enSembl)ENSG00000119922
Phylogenetic Trees/Animal Genes : TreeFamIFIT2
HOVERGENP09913
HOGENOMP09913
Homologs : HomoloGeneIFIT2
Homology/Alignments : Family Browser (UCSC)IFIT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFIT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFIT2
dbVarIFIT2
ClinVarIFIT2
1000_GenomesIFIT2 
Exome Variant ServerIFIT2
ExAC (Exome Aggregation Consortium)IFIT2 (select the gene name)
Genetic variants : HAPMAP3433
Genomic Variants (DGV)IFIT2 [DGVbeta]
DECIPHERIFIT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFIT2 
Mutations
ICGC Data PortalIFIT2 
TCGA Data PortalIFIT2 
Broad Tumor PortalIFIT2
OASIS PortalIFIT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFIT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFIT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFIT2
DgiDB (Drug Gene Interaction Database)IFIT2
DoCM (Curated mutations)IFIT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFIT2 (select a term)
intoGenIFIT2
Cancer3DIFIT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147040   
Orphanet
MedgenIFIT2
Genetic Testing Registry IFIT2
NextProtP09913 [Medical]
TSGene3433
GENETestsIFIT2
Target ValidationIFIT2
Huge Navigator IFIT2 [HugePedia]
snp3D : Map Gene to Disease3433
BioCentury BCIQIFIT2
ClinGenIFIT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3433
Chemical/Pharm GKB GenePA29650
Clinical trialIFIT2
Miscellaneous
canSAR (ICR)IFIT2 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFIT2
EVEXIFIT2
GoPubMedIFIT2
iHOPIFIT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:03:40 CEST 2017

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