Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IFITM1 (interferon induced transmembrane protein 1)

Identity

Alias (NCBI)9-27
CD225
DSPA2a
IFI17
LEU13
HGNC (Hugo) IFITM1
HGNC Alias symb9-27
CD225
DSPA2a
HGNC Alias nameinterferon-induced transmembrane protein 1
 dispanin subfamily A member 2a
HGNC Previous nameIFI17
HGNC Previous nameinterferon induced transmembrane protein 1 (9-27)
LocusID (NCBI) 8519
Atlas_Id 43707
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 314040 and ends at 315272 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IFITM1 (11p15.5) / CRIM1 (2p22.3)SLC1A3 (5p13.2) / IFITM1 (11p15.5)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)IFITM1   5412
Cards
Entrez_Gene (NCBI)IFITM1    interferon induced transmembrane protein 1
Aliases9-27; CD225; DSPA2a; IFI17; 
LEU13
GeneCards (Weizmann)IFITM1
Ensembl hg19 (Hinxton)ENSG00000185885 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185885 [Gene_View]  ENSG00000185885 [Sequence]  chr11:314040-315272 [Contig_View]  IFITM1 [Vega]
ICGC DataPortalENSG00000185885
TCGA cBioPortalIFITM1
AceView (NCBI)IFITM1
Genatlas (Paris)IFITM1
SOURCE (Princeton)IFITM1
Genetics Home Reference (NIH)IFITM1
Genomic and cartography
GoldenPath hg38 (UCSC)IFITM1  -     chr11:314040-315272 +  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFITM1  -     11p15.5   [Description]    (hg19-Feb_2009)
GoldenPathIFITM1 - 11p15.5 [CytoView hg19]  IFITM1 - 11p15.5 [CytoView hg38]
ImmunoBaseENSG00000185885
genome Data Viewer NCBIIFITM1 [Mapview hg19]  
OMIM604456   
Gene and transcription
Genbank (Entrez)AK290480 BC000897 BT007173 J04164 X84958
RefSeq transcript (Entrez)NM_003641
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFITM1
Alternative Splicing GalleryENSG00000185885
Gene ExpressionIFITM1 [ NCBI-GEO ]   IFITM1 [ EBI - ARRAY_EXPRESS ]   IFITM1 [ SEEK ]   IFITM1 [ MEM ]
Gene Expression Viewer (FireBrowse)IFITM1 [ Firebrowse - Broad ]
GenevisibleExpression of IFITM1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8519
GTEX Portal (Tissue expression)IFITM1
Human Protein AtlasENSG00000185885-IFITM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13164   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP13164  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP13164
Splice isoforms : SwissVarP13164
PhosPhoSitePlusP13164
Domains : Interpro (EBI)CD225/Dispanin_fam   
Domain families : Pfam (Sanger)CD225 (PF04505)   
Domain families : Pfam (NCBI)pfam04505   
Conserved Domain (NCBI)IFITM1
Blocks (Seattle)IFITM1
SuperfamilyP13164
Human Protein Atlas [tissue]ENSG00000185885-IFITM1 [tissue]
Peptide AtlasP13164
HPRD05122
IPIIPI00300620   IPI00940995   
Protein Interaction databases
DIP (DOE-UCLA)P13164
IntAct (EBI)P13164
BioGRIDIFITM1
STRING (EMBL)IFITM1
ZODIACIFITM1
Ontologies - Pathways
QuickGOP13164
Ontology : AmiGOossification  protein binding  plasma membrane  plasma membrane  cell surface receptor signaling pathway  negative regulation of cell proliferation  response to virus  membrane  integral component of membrane  negative regulation of cell migration  protein-containing complex  response to interferon-gamma  response to interferon-gamma  response to interferon-alpha  response to interferon-alpha  response to interferon-beta  response to interferon-beta  negative regulation of viral genome replication  negative regulation of viral genome replication  negative regulation of viral genome replication  positive regulation of osteoblast differentiation  negative regulation of viral entry into host cell  negative regulation of viral entry into host cell  regulation of immune response  defense response to virus  type I interferon signaling pathway  type I interferon signaling pathway  
Ontology : EGO-EBIossification  protein binding  plasma membrane  plasma membrane  cell surface receptor signaling pathway  negative regulation of cell proliferation  response to virus  membrane  integral component of membrane  negative regulation of cell migration  protein-containing complex  response to interferon-gamma  response to interferon-gamma  response to interferon-alpha  response to interferon-alpha  response to interferon-beta  response to interferon-beta  negative regulation of viral genome replication  negative regulation of viral genome replication  negative regulation of viral genome replication  positive regulation of osteoblast differentiation  negative regulation of viral entry into host cell  negative regulation of viral entry into host cell  regulation of immune response  defense response to virus  type I interferon signaling pathway  type I interferon signaling pathway  
Pathways : KEGGB cell receptor signaling pathway   
NDEx NetworkIFITM1
Atlas of Cancer Signalling NetworkIFITM1
Wikipedia pathwaysIFITM1
Orthology - Evolution
OrthoDB8519
GeneTree (enSembl)ENSG00000185885
Phylogenetic Trees/Animal Genes : TreeFamIFITM1
HOGENOMP13164
Homologs : HomoloGeneIFITM1
Homology/Alignments : Family Browser (UCSC)IFITM1
Gene fusions - Rearrangements
Fusion : QuiverIFITM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFITM1 [hg38]
dbVarIFITM1
ClinVarIFITM1
MonarchIFITM1
1000_GenomesIFITM1 
Exome Variant ServerIFITM1
GNOMAD BrowserENSG00000185885
Varsome BrowserIFITM1
Genomic Variants (DGV)IFITM1 [DGVbeta]
DECIPHERIFITM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFITM1 
Mutations
ICGC Data PortalIFITM1 
TCGA Data PortalIFITM1 
Broad Tumor PortalIFITM1
OASIS PortalIFITM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFITM1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DIFITM1
Mutations and Diseases : HGMDIFITM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFITM1
DgiDB (Drug Gene Interaction Database)IFITM1
DoCM (Curated mutations)IFITM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFITM1 (select a term)
intoGenIFITM1
Cancer3DIFITM1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604456   
Orphanet
DisGeNETIFITM1
MedgenIFITM1
Genetic Testing Registry IFITM1
NextProtP13164 [Medical]
GENETestsIFITM1
Target ValidationIFITM1
Huge Navigator IFITM1 [HugePedia]
ClinGenIFITM1
Clinical trials, drugs, therapy
MyCancerGenomeIFITM1
Protein Interactions : CTD
Pharm GKB GenePA29653
PharosP13164
Clinical trialIFITM1
Miscellaneous
canSAR (ICR)IFITM1 (select the gene name)
HarmonizomeIFITM1
DataMed IndexIFITM1
Probes
Litterature
PubMed82 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXIFITM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:19:43 CET 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.