Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IFITM2 (interferon induced transmembrane protein 2)

Identity

Alias_namesinterferon induced transmembrane protein 2 (1-8D)
Alias_symbol (synonym)1-8D
Other aliasDSPA2c
HGNC (Hugo) IFITM2
LocusID (NCBI) 10581
Atlas_Id 51270
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 308107 and ends at 309410 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IFITM2 (11p15.5) / HLA-A (6p22.1)IFITM2 (11p15.5) / HNRNPM (19p13.2)IFITM2 (11p15.5) / IFITM2 (11p15.5)
IFITM2 (11p15.5) / NMI (2q23.3)IFITM2 (11p15.5) / SLCO4A1 (20q13.33)STAT6 (12q13.3) / IFITM2 (11p15.5)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFITM2   5413
Cards
Entrez_Gene (NCBI)IFITM2  10581  interferon induced transmembrane protein 2
Aliases1-8D; DSPA2c
GeneCards (Weizmann)IFITM2
Ensembl hg19 (Hinxton)ENSG00000185201 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185201 [Gene_View]  ENSG00000185201 [Sequence]  chr11:308107-309410 [Contig_View]  IFITM2 [Vega]
ICGC DataPortalENSG00000185201
TCGA cBioPortalIFITM2
AceView (NCBI)IFITM2
Genatlas (Paris)IFITM2
WikiGenes10581
SOURCE (Princeton)IFITM2
Genetics Home Reference (NIH)IFITM2
Genomic and cartography
GoldenPath hg38 (UCSC)IFITM2  -     chr11:308107-309410 +  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFITM2  -     11p15.5   [Description]    (hg19-Feb_2009)
EnsemblIFITM2 - 11p15.5 [CytoView hg19]  IFITM2 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBIIFITM2 [Mapview hg19]  IFITM2 [Mapview hg38]
OMIM605578   
Gene and transcription
Genbank (Entrez)BC009696 BG164993 BG257141 BT009859 CR456894
RefSeq transcript (Entrez)NM_006435
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFITM2
Cluster EST : UnigeneHs.709321 [ NCBI ]
CGAP (NCI)Hs.709321
Alternative Splicing GalleryENSG00000185201
Gene ExpressionIFITM2 [ NCBI-GEO ]   IFITM2 [ EBI - ARRAY_EXPRESS ]   IFITM2 [ SEEK ]   IFITM2 [ MEM ]
Gene Expression Viewer (FireBrowse)IFITM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10581
GTEX Portal (Tissue expression)IFITM2
Human Protein AtlasENSG00000185201-IFITM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01629   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01629  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01629
Splice isoforms : SwissVarQ01629
PhosPhoSitePlusQ01629
Domains : Interpro (EBI)CD225/Dispanin_fam   
Domain families : Pfam (Sanger)CD225 (PF04505)   
Domain families : Pfam (NCBI)pfam04505   
Conserved Domain (NCBI)IFITM2
DMDM Disease mutations10581
Blocks (Seattle)IFITM2
SuperfamilyQ01629
Human Protein Atlas [tissue]ENSG00000185201-IFITM2 [tissue]
Peptide AtlasQ01629
HPRD05718
IPIIPI00008922   IPI00453475   IPI00955481   IPI00983101   IPI00983703   IPI00871741   
Protein Interaction databases
DIP (DOE-UCLA)Q01629
IntAct (EBI)Q01629
FunCoupENSG00000185201
BioGRIDIFITM2
STRING (EMBL)IFITM2
ZODIACIFITM2
Ontologies - Pathways
QuickGOQ01629
Ontology : AmiGOplasma membrane  plasma membrane  immune response  response to virus  integral component of membrane  protein-containing complex  response to interferon-gamma  response to interferon-gamma  response to interferon-alpha  response to interferon-alpha  response to interferon-beta  response to interferon-beta  negative regulation of viral genome replication  negative regulation of viral genome replication  negative regulation of viral entry into host cell  negative regulation of viral entry into host cell  defense response to virus  type I interferon signaling pathway  type I interferon signaling pathway  
Ontology : EGO-EBIplasma membrane  plasma membrane  immune response  response to virus  integral component of membrane  protein-containing complex  response to interferon-gamma  response to interferon-gamma  response to interferon-alpha  response to interferon-alpha  response to interferon-beta  response to interferon-beta  negative regulation of viral genome replication  negative regulation of viral genome replication  negative regulation of viral entry into host cell  negative regulation of viral entry into host cell  defense response to virus  type I interferon signaling pathway  type I interferon signaling pathway  
NDEx NetworkIFITM2
Atlas of Cancer Signalling NetworkIFITM2
Wikipedia pathwaysIFITM2
Orthology - Evolution
OrthoDB10581
GeneTree (enSembl)ENSG00000185201
Phylogenetic Trees/Animal Genes : TreeFamIFITM2
HOVERGENQ01629
HOGENOMQ01629
Homologs : HomoloGeneIFITM2
Homology/Alignments : Family Browser (UCSC)IFITM2
Gene fusions - Rearrangements
Fusion : QuiverIFITM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFITM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFITM2
dbVarIFITM2
ClinVarIFITM2
1000_GenomesIFITM2 
Exome Variant ServerIFITM2
ExAC (Exome Aggregation Consortium)ENSG00000185201
GNOMAD BrowserENSG00000185201
Varsome BrowserIFITM2
Genetic variants : HAPMAP10581
Genomic Variants (DGV)IFITM2 [DGVbeta]
DECIPHERIFITM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFITM2 
Mutations
ICGC Data PortalIFITM2 
TCGA Data PortalIFITM2 
Broad Tumor PortalIFITM2
OASIS PortalIFITM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFITM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFITM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFITM2
DgiDB (Drug Gene Interaction Database)IFITM2
DoCM (Curated mutations)IFITM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFITM2 (select a term)
intoGenIFITM2
Cancer3DIFITM2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605578   
Orphanet
DisGeNETIFITM2
MedgenIFITM2
Genetic Testing Registry IFITM2
NextProtQ01629 [Medical]
TSGene10581
GENETestsIFITM2
Target ValidationIFITM2
Huge Navigator IFITM2 [HugePedia]
snp3D : Map Gene to Disease10581
BioCentury BCIQIFITM2
ClinGenIFITM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10581
Chemical/Pharm GKB GenePA29654
Clinical trialIFITM2
Miscellaneous
canSAR (ICR)IFITM2 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFITM2
EVEXIFITM2
GoPubMedIFITM2
iHOPIFITM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:12:37 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.