Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

IFITM3 (interferon induced transmembrane protein 3)

Identity

Alias_namesinterferon induced transmembrane protein 3 (1-8U)
Alias_symbol (synonym)1-8U
Other aliasDSPA2b
IP15
HGNC (Hugo) IFITM3
LocusID (NCBI) 10410
Atlas_Id 50373
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 319673 and ends at 320914 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IFITM3   5414
Cards
Entrez_Gene (NCBI)IFITM3  10410  interferon induced transmembrane protein 3
Aliases1-8U; DSPA2b; IP15
GeneCards (Weizmann)IFITM3
Ensembl hg19 (Hinxton)ENSG00000142089 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142089 [Gene_View]  ENSG00000142089 [Sequence]  chr11:319673-320914 [Contig_View]  IFITM3 [Vega]
ICGC DataPortalENSG00000142089
TCGA cBioPortalIFITM3
AceView (NCBI)IFITM3
Genatlas (Paris)IFITM3
WikiGenes10410
SOURCE (Princeton)IFITM3
Genetics Home Reference (NIH)IFITM3
Genomic and cartography
GoldenPath hg38 (UCSC)IFITM3  -     chr11:319673-320914 -  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFITM3  -     11p15.5   [Description]    (hg19-Feb_2009)
EnsemblIFITM3 - 11p15.5 [CytoView hg19]  IFITM3 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBIIFITM3 [Mapview hg19]  IFITM3 [Mapview hg38]
OMIM605579   614680   
Gene and transcription
Genbank (Entrez)AI355192 AK292173 BC006794 BC008417 BC022439
RefSeq transcript (Entrez)NM_021034
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFITM3
Cluster EST : UnigeneHs.374650 [ NCBI ]
CGAP (NCI)Hs.374650
Alternative Splicing GalleryENSG00000142089
Gene ExpressionIFITM3 [ NCBI-GEO ]   IFITM3 [ EBI - ARRAY_EXPRESS ]   IFITM3 [ SEEK ]   IFITM3 [ MEM ]
Gene Expression Viewer (FireBrowse)IFITM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10410
GTEX Portal (Tissue expression)IFITM3
Human Protein AtlasENSG00000142089-IFITM3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01628   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01628  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01628
Splice isoforms : SwissVarQ01628
PhosPhoSitePlusQ01628
Domains : Interpro (EBI)CD225/Dispanin_fam   
Domain families : Pfam (Sanger)CD225 (PF04505)   
Domain families : Pfam (NCBI)pfam04505   
Conserved Domain (NCBI)IFITM3
DMDM Disease mutations10410
Blocks (Seattle)IFITM3
SuperfamilyQ01628
Human Protein Atlas [tissue]ENSG00000142089-IFITM3 [tissue]
Peptide AtlasQ01628
HPRD05719
IPIIPI00303726   IPI00748544   IPI00982744   
Protein Interaction databases
DIP (DOE-UCLA)Q01628
IntAct (EBI)Q01628
FunCoupENSG00000142089
BioGRIDIFITM3
STRING (EMBL)IFITM3
ZODIACIFITM3
Ontologies - Pathways
QuickGOQ01628
Ontology : AmiGOprotein binding  lysosomal membrane  plasma membrane  plasma membrane  plasma membrane  immune response  response to virus  integral component of membrane  late endosome membrane  negative regulation of viral transcription  response to interferon-gamma  response to interferon-gamma  response to interferon-alpha  response to interferon-alpha  response to interferon-beta  response to interferon-beta  negative regulation of viral genome replication  negative regulation of viral genome replication  negative regulation of viral entry into host cell  negative regulation of viral entry into host cell  negative regulation of viral entry into host cell  defense response to virus  defense response to virus  type I interferon signaling pathway  type I interferon signaling pathway  
Ontology : EGO-EBIprotein binding  lysosomal membrane  plasma membrane  plasma membrane  plasma membrane  immune response  response to virus  integral component of membrane  late endosome membrane  negative regulation of viral transcription  response to interferon-gamma  response to interferon-gamma  response to interferon-alpha  response to interferon-alpha  response to interferon-beta  response to interferon-beta  negative regulation of viral genome replication  negative regulation of viral genome replication  negative regulation of viral entry into host cell  negative regulation of viral entry into host cell  negative regulation of viral entry into host cell  defense response to virus  defense response to virus  type I interferon signaling pathway  type I interferon signaling pathway  
NDEx NetworkIFITM3
Atlas of Cancer Signalling NetworkIFITM3
Wikipedia pathwaysIFITM3
Orthology - Evolution
OrthoDB10410
GeneTree (enSembl)ENSG00000142089
Phylogenetic Trees/Animal Genes : TreeFamIFITM3
HOVERGENQ01628
HOGENOMQ01628
Homologs : HomoloGeneIFITM3
Homology/Alignments : Family Browser (UCSC)IFITM3
Gene fusions - Rearrangements
Fusion : QuiverIFITM3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFITM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFITM3
dbVarIFITM3
ClinVarIFITM3
1000_GenomesIFITM3 
Exome Variant ServerIFITM3
ExAC (Exome Aggregation Consortium)ENSG00000142089
GNOMAD BrowserENSG00000142089
Varsome BrowserIFITM3
Genetic variants : HAPMAP10410
Genomic Variants (DGV)IFITM3 [DGVbeta]
DECIPHERIFITM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFITM3 
Mutations
ICGC Data PortalIFITM3 
TCGA Data PortalIFITM3 
Broad Tumor PortalIFITM3
OASIS PortalIFITM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFITM3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFITM3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFITM3
DgiDB (Drug Gene Interaction Database)IFITM3
DoCM (Curated mutations)IFITM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFITM3 (select a term)
intoGenIFITM3
Cancer3DIFITM3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605579    614680   
Orphanet
DisGeNETIFITM3
MedgenIFITM3
Genetic Testing Registry IFITM3
NextProtQ01628 [Medical]
TSGene10410
GENETestsIFITM3
Target ValidationIFITM3
Huge Navigator IFITM3 [HugePedia]
snp3D : Map Gene to Disease10410
BioCentury BCIQIFITM3
ClinGenIFITM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10410
Chemical/Pharm GKB GenePA29655
Clinical trialIFITM3
Miscellaneous
canSAR (ICR)IFITM3 (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFITM3
EVEXIFITM3
GoPubMedIFITM3
iHOPIFITM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 11:28:26 CEST 2018
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.