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IFITM3 (interferon induced transmembrane protein 3)

Identity

Other names1-8U
DSPA2b
IP15
HGNC (Hugo) IFITM3
LocusID (NCBI) 10410
Location 11p15.5
Location_base_pair Starts at 319673 and ends at 320914 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IFITM3   5414
Entrez_Gene (NCBI)IFITM3  10410  interferon induced transmembrane protein 3
Cards
GeneCards (Weizmann)IFITM3
Ensembl (Hinxton)ENSG00000142089 [Gene_View]  chr11:319673-320914 [Contig_View]  IFITM3 [Vega]
AceView (NCBI)IFITM3
Genatlas (Paris)IFITM3
SOURCE (Stanford)NM_021034
Genomic and cartography
GoldenPath (UCSC)IFITM3  -  11p15.5   chr11:319673-320914 -  11p15.5   [Description]    (hg19-Feb_2009)
EnsemblIFITM3 - 11p15.5 [CytoView]
Mapping of homologs : NCBIIFITM3 [Mapview]
OMIM605579   614680   
Gene and transcription
Genbank (Entrez)AI355192 AK292173 AM392723 AM393694 BC006794
RefSeq transcript (SRS)NM_021034
RefSeq transcript (Entrez)NM_021034
RefSeq genomic (SRS)AC_000143 NC_000011 NC_018922 NG_032755 NT_009237 NW_001838015 NW_004078070
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_032755 NT_009237 NW_001838015 NW_004078070
Consensus coding sequences : CCDS (NCBI)IFITM3
Cluster EST : UnigeneHs.374650 [ SRS ] Hs.374650 [ NCBI ]
CGAP (NCI)Hs.374650
Alternative Splicing : Fast-db (Paris)GSHG0005432
Alternative Splicing GalleryENSG00000142089
Gene ExpressionIFITM3 [ NCBI-GEO ]   IFITM3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01628 (SRS) Q01628 (Uniprot)
NextProtQ01628
With graphics : InterProQ01628
Splice isoforms : SwissVarQ01628(Swissvar)
Domains : Interpro (SRS)Interferon-induced_TM_protein   
Domains : Interpro (EBI)Interferon-induced_TM_protein   
Related proteins : CluSTrQ01628
Domain families : Pfam (SRS)CD225 (PF04505)   
Domain families : Pfam (Sanger)CD225 (PF04505)   
Domain families : Pfam (NCBI)pfam04505   
DMDM10410
Blocks (Seattle)Q01628
Human Protein AtlasENSG00000142089
HPRD05719
IPIIPI00303726   IPI00748544   IPI00982744   
Protein Interaction databases
DIP (DOE-UCLA)Q01628
IntAct (EBI)Q01628
FunCoupENSG00000142089
REACTOMEIFITM3
Protein Interaction Database10410
BioGRIDIFITM3
InParanoidQ01628
Interologous Interaction database Q01628
IntegromeDBIFITM3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)IFITM3
SNP (GeneSNP Utah)IFITM3
SNP : HGBaseIFITM3
Genetic variants : HAPMAPIFITM3
Somatic Mutations in Cancer : COSMICIFITM3 
CONAN: Copy Number AnalysisIFITM3 
Mutations and Diseases : HGMDIFITM3
OMIM605579    614680   
GENETests605579    614680   
Disease Genetic AssociationIFITM3
Huge Navigator IFITM3 [HugePedia]  IFITM3 [HugeCancerGEM]
Genomic VariantsIFITM3  IFITM3 [DGVbeta]
ClinVarIFITM3
snp3D : Map Gene to Disease10410
General knowledge
Homologs : HomoloGeneIFITM3
Homology/Alignments : Family Browser (UCSC)IFITM3
Phylogenetic Trees/Animal Genes : TreeFamIFITM3
Chemical/Protein Interactions : CTD10410
Chemical/Pharm GKB GenePA29655
Clinical trialIFITM3
Cancer Resource (Charite)ENSG00000142089
Ontology : AmiGOlysosomal membrane  plasma membrane  plasma membrane  immune response  response to virus  integral to membrane  cytokine-mediated signaling pathway  late endosome membrane  negative regulation of viral transcription  response to interferon-gamma  response to interferon-alpha  response to interferon-beta  negative regulation of viral genome replication  negative regulation of viral entry into host cell  defense response to virus  type I interferon-mediated signaling pathway  
Ontology : EGO-EBIlysosomal membrane  plasma membrane  plasma membrane  immune response  response to virus  integral to membrane  cytokine-mediated signaling pathway  late endosome membrane  negative regulation of viral transcription  response to interferon-gamma  response to interferon-alpha  response to interferon-beta  negative regulation of viral genome replication  negative regulation of viral entry into host cell  defense response to virus  type I interferon-mediated signaling pathway  
Other databases
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
PubGeneIFITM3
iHOPIFITM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:59:54 CEST 2013
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