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IFNA21 (interferon alpha 21)

Identity

Alias_symbol (synonym)IFN-alphaI
Other aliasLeIF F
leIF-F
HGNC (Hugo) IFNA21
LocusID (NCBI) 3452
Atlas_Id 56167
Location 9p21.3  [Link to chromosome band 9p21]
Location_base_pair Starts at 21165637 and ends at 21166660 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFNA21   5424
Cards
Entrez_Gene (NCBI)IFNA21  3452  interferon alpha 21
AliasesIFN-alphaI; LeIF; leIF-F
GeneCards (Weizmann)IFNA21
Ensembl hg19 (Hinxton)ENSG00000137080 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137080 [Gene_View]  chr9:21165637-21166660 [Contig_View]  IFNA21 [Vega]
ICGC DataPortalENSG00000137080
TCGA cBioPortalIFNA21
AceView (NCBI)IFNA21
Genatlas (Paris)IFNA21
WikiGenes3452
SOURCE (Princeton)IFNA21
Genetics Home Reference (NIH)IFNA21
Genomic and cartography
GoldenPath hg38 (UCSC)IFNA21  -     chr9:21165637-21166660 -  9p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFNA21  -     9p21.3   [Description]    (hg19-Feb_2009)
EnsemblIFNA21 - 9p21.3 [CytoView hg19]  IFNA21 - 9p21.3 [CytoView hg38]
Mapping of homologs : NCBIIFNA21 [Mapview hg19]  IFNA21 [Mapview hg38]
OMIM147584   
Gene and transcription
Genbank (Entrez)BC069329 BC069372 BC069408 BC096699 BC101638
RefSeq transcript (Entrez)NM_002175
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFNA21
Cluster EST : UnigeneHs.113211 [ NCBI ]
CGAP (NCI)Hs.113211
Alternative Splicing GalleryENSG00000137080
Gene ExpressionIFNA21 [ NCBI-GEO ]   IFNA21 [ EBI - ARRAY_EXPRESS ]   IFNA21 [ SEEK ]   IFNA21 [ MEM ]
Gene Expression Viewer (FireBrowse)IFNA21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3452
GTEX Portal (Tissue expression)IFNA21
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01568   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01568  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01568
Splice isoforms : SwissVarP01568
PhosPhoSitePlusP01568
Domaine pattern : Prosite (Expaxy)INTERFERON_A_B_D (PS00252)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Interferon_alpha/beta/delta   
Domain families : Pfam (Sanger)Interferon (PF00143)   
Domain families : Pfam (NCBI)pfam00143   
Domain families : Smart (EMBL)IFabd (SM00076)  
Conserved Domain (NCBI)IFNA21
DMDM Disease mutations3452
Blocks (Seattle)IFNA21
SuperfamilyP01568
Human Protein AtlasENSG00000137080
Peptide AtlasP01568
HPRD00968
IPIIPI00307189   
Protein Interaction databases
DIP (DOE-UCLA)P01568
IntAct (EBI)P01568
FunCoupENSG00000137080
BioGRIDIFNA21
STRING (EMBL)IFNA21
ZODIACIFNA21
Ontologies - Pathways
QuickGOP01568
Ontology : AmiGOadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  cytokine receptor binding  type I interferon receptor binding  extracellular region  extracellular space  humoral immune response  blood coagulation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  innate immune response  defense response to virus  type I interferon signaling pathway  regulation of type I interferon-mediated signaling pathway  
Ontology : EGO-EBIadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  cytokine receptor binding  type I interferon receptor binding  extracellular region  extracellular space  humoral immune response  blood coagulation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  innate immune response  defense response to virus  type I interferon signaling pathway  regulation of type I interferon-mediated signaling pathway  
Pathways : KEGG   
NDEx NetworkIFNA21
Atlas of Cancer Signalling NetworkIFNA21
Wikipedia pathwaysIFNA21
Orthology - Evolution
OrthoDB3452
GeneTree (enSembl)ENSG00000137080
Phylogenetic Trees/Animal Genes : TreeFamIFNA21
HOVERGENP01568
HOGENOMP01568
Homologs : HomoloGeneIFNA21
Homology/Alignments : Family Browser (UCSC)IFNA21
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFNA21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFNA21
dbVarIFNA21
ClinVarIFNA21
1000_GenomesIFNA21 
Exome Variant ServerIFNA21
ExAC (Exome Aggregation Consortium)IFNA21 (select the gene name)
Genetic variants : HAPMAP3452
Genomic Variants (DGV)IFNA21 [DGVbeta]
DECIPHERIFNA21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFNA21 
Mutations
ICGC Data PortalIFNA21 
TCGA Data PortalIFNA21 
Broad Tumor PortalIFNA21
OASIS PortalIFNA21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFNA21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFNA21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFNA21
DgiDB (Drug Gene Interaction Database)IFNA21
DoCM (Curated mutations)IFNA21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFNA21 (select a term)
intoGenIFNA21
Cancer3DIFNA21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147584   
Orphanet
MedgenIFNA21
Genetic Testing Registry IFNA21
NextProtP01568 [Medical]
TSGene3452
GENETestsIFNA21
Target ValidationIFNA21
Huge Navigator IFNA21 [HugePedia]
snp3D : Map Gene to Disease3452
BioCentury BCIQIFNA21
ClinGenIFNA21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3452
Chemical/Pharm GKB GenePA29663
Clinical trialIFNA21
Miscellaneous
canSAR (ICR)IFNA21 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFNA21
EVEXIFNA21
GoPubMedIFNA21
iHOPIFNA21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:12:47 CEST 2017

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